Results 1 to 10 of about 45,447 (273)

Dihydropyridine calcium blockers do not interfere with non-rapid eye movement sleep

Frontiers in Neuroscience, 2022
Non-rapid eye movement (NREM) sleep is tightly homeostatically regulated and essential for survival. In the electroencephalogram (EEG), oscillations in the delta (0.5–4 Hz) range are prominent during NREM sleep. These delta oscillations are, to date, the
GoEun Han, Sumire Matsumoto, Javier Diaz, Robert W. Greene, Robert W. Greene, Kaspar E. Vogt   +5 more
doaj   +1 more source

A Dihydropyridine Derivative as a Highly Selective Fluorometric Probe for Quantification of Au³⁺ Residue in Gold Nanoparticle Solution

Sensors, 2022
Novel dihydroquinoline derivatives (DHP and DHP-OH) were synthesized in one pot via a tandem trimerization-cyclization of methylpropiolate. DHP and DHP-OH possess strong blue fluorescence with high quantum efficiencies over 0.70 in aqueous media.
Waroton Paisuwan, Mongkol Sukwattanasinitt, Mamoru Tobisu, Anawat Ajavakom   +3 more
doaj   +1 more source

RETRACTED: Synthesis of efficient cobalt–metal organic framework as reusable nanocatalyst in the synthesis of new 1,4-dihydropyridine derivatives with antioxidant activity

Frontiers in Chemistry, 2022
Efficient cobalt–metal organic framework (Co-MOF) was prepared via a controllable microwave-assisted reverse micelle synthesis route. The products were characterized by SEM image, N2 adsorption/desorption isotherm, FTIR spectrum, and TG analysis. Results
Omar dheyauldeen Salahdin, Indrajit Patra, Mohammad Javed Ansari, Samar Emad Izzat, Khusniddin Fakhriddinovich Uktamov, Mohammed Kadhem Abid, Ahmed B. Mahdi, Ali Thaeer Hammid, Yasser Fakri Mustafa, Himanshu Sharma   +9 more
doaj   +1 more source

Amlodipine Overdose: Is High Dose Insulin Ready for Prime Time

Hearts, 2022
Overdose of amlodipine, a dihydropyridine calcium channel blocker (CCB), is distinguished from other CCBs due to longer plasma half-life of 30 to 58 h.
Mary Jo S. Farmer, Anisha Contractor, Joshua Allgaier   +2 more
doaj   +1 more source

1,4-Dihydropyridine as a Promising Scaffold for Novel Antimicrobials Against Helicobacter pylori

Frontiers in Microbiology, 2022
The increasing occurrence of multidrug-resistant strains of the gastric carcinogenic bacterium Helicobacter pylori threatens the efficacy of current eradication therapies.
Andrés González, Andrés González, Andrés González, Andrés González, Javier Casado, Javier Casado, Miyase Gözde Gündüz, Brisa Santos, Adrián Velázquez-Campoy, Adrián Velázquez-Campoy, Adrián Velázquez-Campoy, Adrián Velázquez-Campoy, Cristina Sarasa-Buisan, Cristina Sarasa-Buisan, María F. Fillat, María F. Fillat, Milagrosa Montes, Milagrosa Montes, Elena Piazuelo, Elena Piazuelo, Elena Piazuelo, Ángel Lanas, Ángel Lanas, Ángel Lanas, Ángel Lanas   +24 more
doaj   +1 more source

Ultrasound-Assisted One‐Pot Synthesis of 9-(Substituted heteroaryl) acridinedione Derivatives

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2021
An efficient green approach for the synthesis of 9-heteroaryl-acridine-1,8-dione derivatives (3a-f) was accomplished via reactions of dimedone (1) with various heteroaromatic aldehydes (2a-f) and ammonium acetate through one-pot multicomponent reactions ...
Mehtap Özgür, Duygu Bayramoğlu
doaj   +1 more source

Tributyl(1-((dimethylamino)(dimethyliminio)methyl)-1,4-dihydropyridin-4-yl)phosphonium Ditrifluoromethanesulfonate

Molbank, 2023
Site-selective functionalization of pyridines is a crucial tool for the synthesis of diverse pharmaceuticals and materials. We introduced diiminium pyridine adducts as highly convenient and potent Lewis acids. We report that tributylphosphine selectively
Yiwei Gong, Jas S. Ward, Kari Rissanen, Florian F. Mulks   +3 more
doaj   +1 more source

MCM-BP as a Novel Nanomagnetic Reusable Basic Catalyst for the one Pot Solvent-Free Synthesis of Dihydropyridine, Polyhydroquinoline and Polyhydroacridine Derivatives via Hantzsch Multicomponent Condensation Reaction [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2020
By the immobilization of bipyridinium chloride onto mesoporous MCM-41encapsulated Fe3O4 nanoparticles via a simple post-synthesis method, a totally new organic-inorganic hybrid nanocomposite was formulated. The heterogeneous hybrid nanomagnetic composite
Manoochehr Aghajeri, Ali Reza Kiasat, Haleh Sanaeishoar   +2 more
doaj   +1 more source

Dihydropyridine Enhances the Antioxidant Capacities of Lactating Dairy Cows under Heat Stress Condition

Animals, 2020
Heat stress (HS), a nonspecific response to environmental heat, can seriously affect dairy cow health. Feed additives may alleviate HS in dairy cows by improving rumen fermentation efficacy, stimulating feed consumption, enhancing vasodilation, and/or ...
Meng-Fei Yu, Xin-Mao Zhao, Hang Cai, Jian-Ming Yi, Guo-Hua Hua   +4 more
doaj   +1 more source

Development of a Rapid Mass Spectrometric Determination of AMP and Cyclic AMP for PDE3 Activity Study: Application and Computational Analysis for Evaluating the Effect of a Novel 2-oxo-1,2-dihydropyridine-3-carbonitrile Derivative as PDE-3 Inhibitor

Molecules, 2020
A simple, quick, easy and cheap tandem mass spectrometry (MS/MS) method for the determination of adenosine monophosphate (AMP) and cyclic adenosine monophosphate (cAMP) has been newly developed.
Ilaria Cicalini, Barbara De Filippis, Nicola Gambacorta, Antonio Di Michele, Silvia Valentinuzzi, Alessandra Ammazzalorso, Alice Della Valle, Rosa Amoroso, Orazio Nicolotti, Piero Del Boccio, Letizia Giampietro   +10 more
doaj   +1 more source