Results 1 to 10 of about 54,488 (353)

Green synthesis, molecular docking and anticancer activity of novel 1,4-dihydropyridine-3,5-Dicarbohydrazones under grind-stone chemistry

Green Chemistry Letters and Reviews, 2020
The reaction of 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarbohydrazide with variety of carbonyl compounds such as substituted benzaldehydes, cycloalkanones and hetero-cyclic ketones under grinding method under catalyst- and solvent-free ...
Sobhi M. Gomha, Zeinab A. Muhammad, Hassan M. Abdel-aziz, Islam K. Matar, Abdelaziz A. El-Sayed   +4 more
doaj   +2 more sources

Anti-Atherosclerotic Potential of Dihydropyridine Calcium Channel Blockers

Journal of Atherosclerosis and Thrombosis, 2012
Dihydropyridine calcium channel blockers (CCBs) are widely used agents for patients with hypertension. Dihydropyridine CCBs lower blood pressure mainly through vasodilation and reduction of peripheral resistance, and several clinical studies have ...
Norio Ishii, T. Matsumura, S. Shimoda, E. Araki   +3 more
exaly   +2 more sources

Synthesis and Characterisation of 1,1′-{[3,5-Bis(dodecyloxy-carbonyl)-4-(thiophen-3-yl)-1,4-dihydropyridine-2,6-diyl]bis-(methylene)}bis(pyridin-1-ium) Dibromide [PDF]

Molbank, 2021
In the present work, construction of double-charged cationic amphiphilic 1,1′-{[3,5-bis(dodecyl¬oxy-carbonyl)-4-(thiophen-3-yl)-1,4-dihydropyridine-2,6-diyl]bis-(methylene)}bis(pyridin-1-ium) dibromide (7) was performed in four steps.
Martins Rucins, Karlis Pajuste, Aiva Plotniece, Nadiia Pikun, Roman Rodik, Sergiy Vyshnevskiy, Arkadij Sobolev   +6 more
doaj   +3 more sources

Myocardial Bridging, Unusual Cause of Myocardial Infarction; Case Report and Review of Literature. [PDF]

Clin Case Rep
ABSTRACT Myocardial bridging is a common coronary anomaly. Although it is considered to be a benign condition, it can rarely be complicated by myocardial infarction. Clinicians should be suspicious of myocardial bridging as an etiology of myocardial infarction when other more common etiologies have been excluded.
Daba M, Bineyam D, Yohannes I, Yohannes B, Waktola R, Bedada E.   +5 more
europepmc   +2 more sources

The Expanding Role of Pyridine and Dihydropyridine Scaffolds in Drug Design

Drug Design, Development and Therapy, 2021
Pyridine-based ring systems are one of the most extensively used heterocycles in the field of drug design, primarily due to their profound effect on pharmacological activity, which has led to the discovery of numerous broad-spectrum therapeutic agents ...
Yong Ling, Zhi-You Hao, Dong Liang, Chun-Lei Zhang, Yanfei Liu, Yan Wang   +5 more
semanticscholar   +1 more source

Dihydropyridine calcium blockers do not interfere with non-rapid eye movement sleep

Frontiers in Neuroscience, 2022
Non-rapid eye movement (NREM) sleep is tightly homeostatically regulated and essential for survival. In the electroencephalogram (EEG), oscillations in the delta (0.5–4 Hz) range are prominent during NREM sleep. These delta oscillations are, to date, the
GoEun Han, Sumire Matsumoto, Javier Diaz, Robert W. Greene, Robert W. Greene, Kaspar E. Vogt   +5 more
doaj   +1 more source

A Dihydropyridine Derivative as a Highly Selective Fluorometric Probe for Quantification of Au³⁺ Residue in Gold Nanoparticle Solution

Sensors, 2022
Novel dihydroquinoline derivatives (DHP and DHP-OH) were synthesized in one pot via a tandem trimerization-cyclization of methylpropiolate. DHP and DHP-OH possess strong blue fluorescence with high quantum efficiencies over 0.70 in aqueous media.
Waroton Paisuwan, Mongkol Sukwattanasinitt, Mamoru Tobisu, Anawat Ajavakom   +3 more
doaj   +1 more source

Amlodipine Overdose: Is High Dose Insulin Ready for Prime Time

Hearts, 2022
Overdose of amlodipine, a dihydropyridine calcium channel blocker (CCB), is distinguished from other CCBs due to longer plasma half-life of 30 to 58 h.
Mary Jo S. Farmer, Anisha Contractor, Joshua Allgaier   +2 more
doaj   +1 more source

Labile Base‐Stabilized Silyliumylidene Ions. Non‐Metallic Species Capable of Activating Multiple Small Molecules

Chemistry – A European Journal, Volume 28, Issue 70, December 15, 2022., 2022
Various base‐stabilized silyliumylidene ions with different ligands were synthesized. Their behaviour appeared strongly dependent on the type of ligand. Indeed, in contrast to the poorly reactive silyliumylidenes stabilized by strongly donating ligands (DMAP, NHC), the sulfide‐supported one (SMe2) exhibits higher reactivity toward various small ...
Raphaël Nougué, Shintaro Takahashi, Aymeric Dajnak, Eddy Maerten, Antoine Baceiredo, Nathalie Saffon‐Merceron, Vicenç Branchadell, Tsuyoshi Kato   +7 more
wiley   +1 more source

RETRACTED: Synthesis of efficient cobalt–metal organic framework as reusable nanocatalyst in the synthesis of new 1,4-dihydropyridine derivatives with antioxidant activity

Frontiers in Chemistry, 2022
Efficient cobalt–metal organic framework (Co-MOF) was prepared via a controllable microwave-assisted reverse micelle synthesis route. The products were characterized by SEM image, N2 adsorption/desorption isotherm, FTIR spectrum, and TG analysis. Results
Omar dheyauldeen Salahdin, Indrajit Patra, Mohammad Javed Ansari, Samar Emad Izzat, Khusniddin Fakhriddinovich Uktamov, Mohammed Kadhem Abid, Ahmed B. Mahdi, Ali Thaeer Hammid, Yasser Fakri Mustafa, Himanshu Sharma   +9 more
doaj   +1 more source