Results 21 to 30 of about 45,447 (273)

Troponin T3 regulates nuclear localization of the calcium channel Cavβ1a subunit in skeletal muscle [PDF]

, 2015
The voltage-gated calcium channel (Cav) β1a subunit (Cavβ1a) plays an important role in excitation-contraction coupling (ECC), a process in the myoplasm that leads to muscle-force generation. Recently, we discovered that the Cavβ1a subunit travels to the
Delbono, Osvaldo, Hereñú, Claudia Beatriz, Jiang, Yang, Messi, Maria Laura, Pereyra, Andrea Soledad, Taylor, Jackson, Wang, Zhong Min, Zhang, Tan   +7 more
core   +2 more sources

Synthesis of Some New Fluorinated Hexahydroquinoline and Acridinedione Derivatives in Trifluoroethanol

Applied Sciences, 2012
This article describes one-pot synthesis of new fluorinated hexahydroquinoline derivatives via unsymmetric Hantzsch reaction involving 5-trifluoromethyl-1,3-cyclohexanedione, aldehydes, acetoacetate ester, and ammonium acetate in trifluoroethanol (TFE ...
Cosmas O. Okoro, Mumiye A. Ogunwale, Tasneem Siddiquee   +2 more
doaj   +1 more source

Synthesis, characterization and Theoretical study of some 2-Oxopyridine Carbonitrile derivatives that contain tetrazole ring and evaluation of their Biological activity

مجلة علوم ذي قار, 2023
A series of 2-oxo-6-[4-(1H-tetrazol-1-yl) phenyl-1,2-dihydropyridine-3-carbonitrile 3,4-dimethoxyphenyl)-2-oxo-6-4-(1H-tetrazol-1-yl) phenyl]-1,2-dihydropyridine-3-carbonitrile and 2-oxo-6-[4-(1H-tetrazol-1-yl) phenyl]-4-(thiophen-2-yl)- 1,2 ...
Athraa Hamed Mekky, Meinaa Jaber Dalal, Athraa G. Sager, Noor Abd Alkhudhur Salmn , Abbas Talib Abd Ali, M.R. Jayapal   +5 more
doaj   +1 more source

Tissue-specific expression of high-voltage-activated dihydropyridine-sensitive L-type calcium channels [PDF]

, 1991
The cloning of the cDNA for the α1 subunit of L-type calcium channels revealed that at least two genes (CaCh1 and CaCh2) exist which give rise to several splice variants.
Caffrey J. M., Catterall W. A., Ellis S. B., Glossmann H., Grabner M., Hofmann F., Hoshi T., Jay S. D., Jongh K. S., Kim H. S., Koch W. J., Koch W. J., Melton D. A., Olson E. N., Perez-Reyes E., Rampe D. E., Reuter H., Ruth P., Ruth P., Sambrook J., Sanger F., Schubert D., Shih H.-T., Snutch T. P., Tanabe T., Thomas P. S., Tsien R. W.   +26 more
core   +2 more sources

3-Methyl 5-{3-[(4-Methylbenzenesulfonyl)oxy]propyl} 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Molbank, 2022
The 1,4-dihydropyridine is a ubiquitous scaffold employed not only in medicinal chemistry but also in organic synthesis, given its ability to act as a hydrogen transfer reagent, thus emulating NAD(P)H reducing agents.
Carlotta Borgarelli, Stijn Lenaers, Wim M. De Borggraeve, Ermal Ismalaj   +3 more
doaj   +1 more source

Blockade of current through single calcium channels by trivalent lanthanide cations. Effect of ionic radius on the rates of ion entry and exit. [PDF]

, 1990
Currents flowing through single dihydropyridine-sensitive Ca2+ channels were recorded from cell-attached patches on C2 myotubes. In the presence of dihydropyridine agonist to prolong the duration of single-channel openings, adding micromolar ...
Lansman, JB
core   +2 more sources

The roles of the subunits in the function of the calcium channel [PDF]

, 1991
Dihydropyridine-sensitive voltage-dependent L-type calcium channels are critical to excitation-secretion and excitation-contraction coupling. The channel molecule is a complex of the main, pore-forming subunit alpha 1 and four additional subunits: alpha ...
Biel, Martin, Dascal, Nathan, Flockerzi, V., Hofmann, Franz, Lotan, I., Singer, D.   +5 more
core   +1 more source

HIVAN and medication use in chronic dialysis patients in the United States: analysis of the USRDS DMMS Wave 2 study

BMC Nephrology, 2003
Background The use and possible effects of factors known to improve outcomes in patients with human immunodeficiency virus associated nephropathy (HIVAN), namely of angiotensin converting enzyme inhibitors (ACE) and antiretroviral therapy, has not been ...
Agodoa Lawrence Y, Trespalacios Fernando C, Abbott Kevin C, Ahuja Tejinder S   +3 more
doaj   +1 more source

Heart rate variability and target organ damage in hypertensive patients [PDF]

, 2012
Background: We evaluated the association between linear standard Heart Rate Variability (HRV) measures and vascular, renal and cardiac target organ damage (TOD).
2003 European Society of Hypertension, A Garcia-Garcia, A Kluttig, A Musialik-Lydka, A Shehab, AI Vinik, AL Goldberger, AS Levey, B Dahlof, D Sahn, DH O'Leary, DJ Brotman, DW Kitzman, EB Schroeder, Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults, G de Simone, G Ferrari, G Iaccarino, G Lembo, G Mancia, G Martini, G Parati, GN Arbolishvili, JF Thayer, K Jensen-Urstad, K Oikawa, KH Tseng, L Pecchia, L Pecchia, LE Chambless, Leandro Pecchia, LM Ueno, Lomb, M Hollander, M Malik, M Zabalgoitia, MW Lorenz, N De Luca, N de Luca, Nicola De Luca, P Alter, P Chandra, P Hamilton, P Melillo, P Melillo, P Melillo, Paolo Melillo, R Izzo, Raffaele Izzo, RB Devereux, RB Devereux, RF Berntsen, RM Lang, S Kodituwakku, S Yusuf, U Rajendra Acharya, Z Bajko   +56 more
core   +4 more sources

Case report on low dose of Cilnidipine: A fourth-generation calcium channel blocker-induced gingival overgrowth

Journal of Indian Society of Periodontology, 2019
Drug-induced gingival overgrowth is a frequently observed adverse effect of antihypertensive drug calcium channel blockers (CCBs). Gingival enlargements are more common with the dihydropyridine class of CCBs.
Sameera Gopinath, Vadakkedath Venugopal Harishkumar, Vediyera Chandroth Santhosh, Sreekanth Puthalath   +3 more
doaj   +1 more source