Results 131 to 140 of about 148,764 (203)

Dihydropyrimidine Dehydrogenase Deficiency (DPYD) Genotyping-Guided Fluoropyrimidine-Based Adjuvant Chemotherapy for Breast Cancer. A Cost-Effectiveness Analysis. [PDF]

Clin Drug Investig
Abushanab D, Mohamed S, Abdel-Latif R, Moustafa DA, Marridi W, Elazzazy S, Badji R, Al-Muftah W, Ismail SI, Bujassoum S, Al-Thani A, Al-Badriyeh D, Al Hail M.   +12 more
europepmc   +1 more source

Dihydropyrimidine Dehydrogenase Phenotyping Using Pretreatment Uracil: A Note of Caution Based on a Large Prospective Clinical Study. [PDF]

Clin Pharmacol Ther, 2022
de With M, Knikman J, de Man FM, Lunenburg CATC, Henricks LM, van Kuilenburg ABP, Maring JG, van Staveren MC, de Vries N, Rosing H, Beijnen JH, Pluim D, Modak A, Imholz ALT, van Schaik RHN, Schellens JHM, Gelderblom H, Cats A, Guchelaar HJ, Mathijssen RHJ, Swen JJ, Meulendijks D.   +21 more
europepmc   +1 more source

Cancer genomic profiling identified dihydropyrimidine dehydrogenase deficiency in bladder cancer promotes sensitivity to gemcitabine. [PDF]

Sci Rep, 2022
Tsukahara S, Shiota M, Takamatsu D, Nagakawa S, Matsumoto T, Kiyokoba R, Yagi M, Setoyama D, Noda N, Matsumoto S, Hayashi T, Contreras-Sanz A, Black PC, Inokuchi J, Kohashi K, Oda Y, Uchiumi T, Eto M, Kang D.   +18 more
europepmc   +1 more source

Management of patients with reduced dihydropyrimidine dehydrogenase activity receiving combined 5-fluoruracil-/capecitabine-based chemoradiotherapy. [PDF]

Strahlenther Onkol
Hoffmann E, Toepell A, Peter A, Böke S, De-Colle C, Steinle M, Niyazi M, Gani C.   +7 more
europepmc   +1 more source

Activation of sphingosine-1-phosphate receptor 2 (S1PR2) upregulates dihydropyrimidine dehydrogenase (DPD) expression in colon cancer cells. [PDF]

J Adv Res
Guo ZK, Wu XF, Tan MY, Liang WS, Yang YM, Chu ZZ, Xu R, Li KQ, Cheng YY, Zhang YZ, Zhang YH, Hai Y, Cui SX, Qu XJ.   +13 more
europepmc   +1 more source

Determination of plasma uracil as a screening for dihydropyrimidine dehydrogenase deficiency: clinical application in oncological treatments. [PDF]

Eur J Hosp Pharm
Tejedor-Tejada E, Rubio Calvo D, García Andreo A.   +2 more
europepmc   +1 more source

Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase ( DPYD )

, 2023
Zhang T, Ambrodji A, Huang H, Bouchonville KJ, Etheridge AS, Schmidt RE, Bembenek BM, Temesgen ZB, Wang Z, Innocenti F, Stroka D, Diasio RB, Largiadèr CR, Offer SM.   +13 more
europepmc   +1 more source

Dihydropyrimidine Dehydrogenase Polymorphism c.2194G>A Screening Is a Useful Tool for Decreasing Gastrointestinal and Hematological Adverse Drug Reaction Risk in Fluoropyrimidine-Treated Patients. [PDF]

Curr Issues Mol Biol
Ardizzone A, Bulzomì M, De Luca F, Silvestris N, Esposito E, Capra AP.   +5 more
europepmc   +1 more source

Dihydropyrimidine dehydrogenase polymorphisms in patients with gastrointestinal malignancies and their impact on fluoropyrimidine tolerability: Experience from a single Italian institution.

World J Gastrointest Oncol
D'Amato M, Iengo G, Massa N, Carlomagno C.   +3 more
europepmc   +1 more source

A ferredoxin-dependent dihydropyrimidine dehydrogenase in Clostridium chromiireducens. [PDF]

Biosci Rep, 2020
Wang F, Wei Y, Lu Q, Ang EL, Zhao H, Zhang Y.   +5 more
europepmc   +1 more source