Results 121 to 130 of about 148,764 (203)

Precision Management of a Patient With Dihydropyrimidine Dehydrogenase Deficiency and Liver-Predominant Metastatic Rectal Cancer Using Hepatic Arterial Floxuridine. [PDF]

JCO Precis Oncol, 2023
Lumish M, Thackray J, Do RKG, Caudle KE, Amstutz U, Schwab M, Diasio RB, Jarnagin WR, Cercek A.   +8 more
europepmc   +1 more source

5-Fluorouracil Neurotoxicity in the Absence of Dihydropyrimidine Dehydrogenase Deficiency Case Report. [PDF]

Neurohospitalist, 2022
Jules R, Thaper A, Foster R, Ameli P, Robinson C, Pizzi M, Babi MA, Maciel CB, Busl KM, Reddy R, Roth W.   +10 more
europepmc   +1 more source

Author Correction: P53 represses pyrimidine catabolic gene dihydropyrimidine dehydrogenase (DPYD) expression in response to thymidylate synthase (TS) targeting. [PDF]

Sci Rep
Gokare P, Finnberg NK, Abbosh PH, Dai J, Murphy ME, El-Deiry WS.   +5 more
europepmc   +1 more source

Correction: Hypoxia Drives Dihydropyrimidine Dehydrogenase Expression in Macrophages and Confers Chemoresistance in Colorectal Cancer. [PDF]

Cancer Res, 2022
Malier M, Gharzeddine K, Laverriere MH, Marsili S, Thomas F, Court M, Decaens T, Roth G, Millet A.   +8 more
europepmc   +1 more source

A thymine-challenge test to prospectively evaluate dihydropyrimidine dehydrogenase activity for risk of severe 5-fluorouracil-induced gastrointestinal toxicity. [PDF]

Cancer Chemother Pharmacol
Helsby N, Sharples K, Kim YJ, Porter D, Burns K, Jeong SH, Benge S, Deva S, Lawrence B, Jackson C, North R, Strother RM, Duley J, Findlay M.   +13 more
europepmc   +1 more source

Concordance of Blood-Based and Normal Tissue-Based Dihydropyrimidine Dehydrogenase (DPYD) Genotyping. [PDF]

Oncologist, 2022
Morelli C, Formica V, Doldo E, Riondino S, Rofei M, Vergilii L, Palmieri G, Arkenau HT, Roselli M, Orlandi A.   +9 more
europepmc   +1 more source

Association between miRNA expression profiles and polymorphisms of dihydropyrimidine dehydrogenase drug-metabolizing gene in patients with colorectal cancer receiving 5-fluorouracil. [PDF]

Biomed Rep
Phannasil P, Chansriwong P, Sirachainan E, Reungwetwattana T, Jinda P, Aiempradit S, Sirilerttrakul S, Sukasem C, Atasilp C.   +8 more
europepmc   +1 more source

Prognostic Impact of Dihydropyrimidine Dehydrogenase Germline Variants in Unresectable Non-Small Cell Lung Cancer Patients Treated with Platin-Based Chemotherapy. [PDF]

Int J Mol Sci, 2023
Guijarro-Eguinoa J, Arjona-Hernandez S, Stewart S, Pernia O, Arias P, Losantos-García I, Rubio T, Burdiel M, Rodriguez-Antolin C, Cruz-Castellanos P, Higuera O, Borobia AM, Rodriguez-Novoa S, de Castro-Carpeño J, Ibanez de Caceres I, Rosas-Alonso R.   +15 more
europepmc   +1 more source

Predicting Dihydropyrimidine Dehydrogenase Deficiency and Related 5-Fluorouracil Toxicity: Opportunities and Challenges of DPYD Exon Sequencing and the Role of Phenotyping Assays. [PDF]

Int J Mol Sci, 2022
De Luca O, Salerno G, De Bernardini D, Torre MS, Simmaco M, Lionetto L, Gentile G, Borro M.   +7 more
europepmc   +1 more source

Intratumoural expression of dihydropyrimidine dehydrogenase is an independent prognostic factor in resected pancreatic ductal adenocarcinoma treated with adjuvant gemcitabine. [PDF]

Oncol Lett
Blomstrand H, Bodarve M, Groth F, Naredi P, Sund M, Vilhav C, Green H, Björnsson B, Öhlund D, Lindblad S, Franklin O, Elander NO.   +11 more
europepmc   +1 more source