Results 111 to 120 of about 148,764 (203)

Dihydropyrimidine Dehydrogenase [NADP( )] [PDF]

, 2020
openaire   +1 more source

Frequency of c.1905+1G>A Mutation in DPD Gene among Patients with Colorectal Cancer in Mazandaran Province

Journal of Mazandaran University of Medical Sciences, 2019
Background and purpose: 5-Flourouracil (5-FU) is one of the most common chemical drugs used in chemotherapy of patients with cancers. Dihydropyrimidine dehydrogenase (DPD) is a critical enzyme in the catabolism of 5-FU.
Hossein Jalali, Ramin Shekarriz, Mohammad Reza Mahdavi   +2 more
doaj  

Quantitative impact of pre-analytical process on plasma uracil when testing for dihydropyrimidine dehydrogenase deficiency. [PDF]

Br J Clin Pharmacol, 2023
Maillard M, Launay M, Royer B, Guitton J, Gautier-Veyret E, Broutin S, Tron C, Le Louedec F, Ciccolini J, Richard D, Alarcan H, Haufroid V, Tafzi N, Schmitt A, Etienne-Grimaldi MC, Narjoz C, Thomas F, Groupe de Pharmacologie Clinique Oncologique (GPCO).   +17 more
europepmc   +1 more source

Dihydropyrimidine Dehydrogenase Inhibitor [PDF]

, 2020
openaire   +1 more source

Testing for Dihydropyrimidine Dehydrogenase Deficiency to Individualize 5-Fluorouracil Therapy. [PDF]

Cancers (Basel), 2022
Diasio RB, Offer SM.
europepmc   +1 more source

DPYD genotyping and dihydropyrimidine dehydrogenase (DPD) phenotyping in clinical oncology. A clinically focused minireview. [PDF]

Basic Clin Pharmacol Toxicol, 2022
Paulsen NH, Vojdeman F, Andersen SE, Bergmann TK, Ewertz M, Plomgaard P, Hansen MR, Esbech PS, Pfeiffer P, Qvortrup C, Damkier P.   +10 more
europepmc   +1 more source

Dihydropyrimidine dehydrogenase modulates immune response to checkpoint inhibition in mismatch repair deficient/microsatellite instability-high colorectal cancer. [PDF]

J Immunother Cancer
Soni S, Battaglin F, Castanon S, Yang Y, Smbatyan G, Torres Gonzalez L, Ho Lo J, Mittal P, Gonzalez E, Baugh AG, Soto Trujillo S, Ashouri K, Algaze S, Jayachandran P, Zhang W, K Singh I, Cerma K, Bergamo F, Lonardi S, Zhang Y, Kay SA, Yu J, Zhang L, Millstein J, T Roussos Torres E, Lenz HJ.   +25 more
europepmc   +1 more source

Genetic Variation in miR-27a Is Associated with Fluoropyrimidine-Associated Toxicity in Patients with Dihydropyrimidine Dehydrogenase Variants after Genotype-Guided Dose Reduction. [PDF]

Int J Mol Sci, 2023
Medwid S, Wigle TJ, Ross C, Kim RB.
europepmc   +1 more source

Optimizing fluoropyrimidine therapy through dihydropyrimidine dehydrogenase polymorphism testing. [PDF]

World J Gastrointest Oncol
Krishnan A.
europepmc   +1 more source

Dihydropyrimidine Dehydrogenase-Mediated Resistance to 5-Fluorouracil: Mechanistic Investigation and Solution. [PDF]

ACS Pharmacol Transl Sci, 2022
Verma H, Narendra G, Raju B, Singh PK, Silakari O.   +4 more
europepmc   +1 more source