Results 101 to 110 of about 611 (196)

Green and Efficient Synthesis of Dihydropyrimidinone Analogues via Hpa-Clay Catalyzed Biginelli Reaction

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry
This study introduces an environmentally sustainable approach for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones (DHPMs), via the Biginelli reaction. A heterogeneous catalyst, Heteropolyacid-Clay (HPA-Clay), is developed by immobilizing H5PV2W10O40 on ...
Nuzhat Rehman, Ayaz Mahmood Dar, Raja Feroz Ahmad Haji, Sharief-ud-din Khan, Deepak Pareek, Saleem Farooq, Bashir Ahmad Dar   +6 more
doaj   +1 more source

Exploring the binding dynamics of anticancer Dihydropyrimidinone derivatives with Serum Albumin: A multispectral approach

Chemical Physics Impact
In this work, we have investigated the synthesis and characterization of two novel anticancer agents, 5-acetyl-6-methyl-4-phenyl-3,4-dihydropyrimidin-2(1H)-one (L1) and 2-Acetyl-4-(3,4-dimethoxy-phenyl)-6-methyl-3,4-dihydro-1H-pyrimidin-2-one (L2 ...
Chandraprakash Gond, Shivani Daksh, Akanksha Mishra, Nikhil Kumar, Anupama Datta, Anjani Kumar Tiwari   +5 more
doaj   +1 more source

Sustainable Biginelli chemistry: Indian contributions to green multicomponent synthesis

Discover Chemistry
The Biginelli Reaction is a one-pot acid-catalysed cyclo-condensation procedure that combines urea, β-ketoester, and aromatic aldehydes to create functionalised DHPMs. For more than a century, this three-component reaction has been recognised as a method
Rajni, Sahil, Neera Raghav, Anjaneyulu Bendi, G. B. Dharma Rao   +4 more
doaj   +1 more source

Benchtop ¹⁹F Nuclear Magnetic Resonance (NMR) Spectroscopy Provides Mechanistic Insight into the Biginelli Condensation toward the Chemical Synthesis of Novel Trifluorinated Dihydro- and Tetrahydropyrimidinones as Antiproliferative Agents. [PDF]

ACS Omega, 2023
Chen R, Singh P, Su S, Kocalar S, Wang X, Mandava N, Venkatesan S, Ferguson A, Rao A, Le E, Rojas C, Njoo E.   +11 more
europepmc   +1 more source

Synthesis of 3,4-Dihydropyrimidin-2(1H)-one-5-carboxamides [PDF]

, 2010
The synthesis of various dihydropyrimidinone derivatives bearing carbamoyl moieties in 5-position under reflux conditions and microwave irradiation is described.
Mousa Soleymani, Hamid Reza Memarian
core  

Mesoionic carbene cobalt complexes as multipurpose catalyst precursors for hydrosilylation and dihydropyrimidinone synthesis [PDF]

, 2021
Albrecht, Martin, Martin Albrecht, Simone Bertini, Bertini, Simone   +3 more
core   +1 more source

Hybrid Dihydropyrimidinones Targeting AKT Signaling: Antitumor Activity in Hormone-Dependent 2D and 3D Cancer Models. [PDF]

Pharmaceutics
Tejada AH, Santos SJ, Lobo GT, Ariwoola AA, Bezerra AJA, Stringhetta GR, Gomes INF, da Silva LS, Reis RMV, Preto DD, Russowsky D, Silva-Oliveira RJ.   +11 more
europepmc   +1 more source

Corrigendum to "Synthesis, characterization and biological profile of some new dihydropyrimidinone derivaties" [Heliyon Volume 11, Issue 1, 15 January 2025, e41152]. [PDF]

Heliyon
Kanwal M, Nadeem H, Malik S, Maqsood S.
europepmc   +1 more source

Design, synthesis and evaluation of fluorescent dihydropyridine-dihydropyrimidinone hybrids as inducers of cell-cycle arrest in a prostate cancer cell line <i>via</i> Aurora kinase interactions. [PDF]

RSC Med Chem
de Souza VP, Gomes INF, Santos SJ, Braga CB, Bezerra AJA, Philot EA, Ramos CRN, Pantaleão SQ, da Silva LS, Pilli RA, Reis RM, Oliveira RJS, Russowsky D.   +12 more
europepmc   +1 more source

Defect-rich MOF-303 as a dual acid-base heterogeneous catalyst for the one-pot Biginelli synthesis of dihydropyrimidinones. [PDF]

Sci Rep
Shaheed N, Shaabani A.
europepmc   +1 more source