Recent Synthetic Chemistry of Dihydropyrimidinones Derivatives: A Review
Dihydropyrimidinones and their derivatives are important class of heterocyclic compound. The synthesis of these bioactive heterocycles has attracted the interest of organic and medicinal chemist due to pharmacological activities associated with this heterocyclic compounds.
Magar, Rameshwar R. +2 more
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Solvent-Free Synthesis of Dihydropyrimidinone by Using Molecular Iodine as Catalyst
Dihydropyrimidinone with diverse pharmacological activities can be obtained through the multicomponent of Biginelli reactions by heating aldehyde, ethyl acetoacetate and urea/thiourea in ethanol with the addition of hydrochloric acid.
Fadlan, Arif +2 more
core
A novel dihydropyrimidinone derivative, 4-(3-ethoxy-4-hydroxyphenyl)-6-methyl-2-oxo-N-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxamide, was synthesized in excellent yield via an ionic liquid-mediated Biginelli condensation and characterized by FT-IR ...
Sugumar SathiyaPriya +5 more
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Benchtop 19F Nuclear Magnetic Resonance (NMR) Spectroscopy Provides Mechanistic Insight into the Biginelli Condensation toward the Chemical Synthesis of Novel Trifluorinated Dihydro- and Tetrahydropyrimidinones as Antiproliferative Agents. [PDF]
Chen R +11 more
europepmc +1 more source
Les dérivés substitués d'aryle sont devenus essentiels en chimie organique synthétique en raison de leur similitude avec l'ADN et l'ARN.
Massilya FERRAT Zineb RAKDI. Enc/ Dr. HABILAT TAHIR
core
<i>Averrhoa bilimbi</i> L. Juice: An efficient natural acid catalyst for the green synthesis of dihydropyrimidinone-1,2,3-triazole. [PDF]
Ardiansah B +6 more
europepmc +1 more source
Antibacterial and molecular docking studies with protein stability studies into dihydropyrimidinones synthesized via silver nanoparticle catalysis: probing structure-activity relationships. [PDF]
Patil R +5 more
europepmc +1 more source
Hybrid Dihydropyrimidinones Targeting AKT Signaling: Antitumor Activity in Hormone-Dependent 2D and 3D Cancer Models. [PDF]
Tejada AH +11 more
europepmc +1 more source
Corrigendum to "Synthesis, characterization and biological profile of some new dihydropyrimidinone derivaties" [Heliyon Volume 11, Issue 1, 15 January 2025, e41152]. [PDF]
Kanwal M, Nadeem H, Malik S, Maqsood S.
europepmc +1 more source
Recyclable CaSiO<sub>3</sub>-Catalyzed Synthesis and Characterization of Indeno[1, 2-d] Pyrimidine Derivatives: In Silico and Preliminary Biological Screening. [PDF]
Kalasapur VV +7 more
europepmc +1 more source

