Results 81 to 90 of about 1,000 (202)
Advances in Pharmacological and Pharmaceutical Sciences, Volume 2025, Issue 1, 2025.Heat‐shock protein 70 (HSP70) and nanotechnology have emerged as promising avenues in glioblastoma multiforme (GBM) therapy, addressing the critical challenges posed by its aggressive nature and therapeutic resistance. HSP70’s dual role in cellular stress response and tumour survival emphasises its potential as both a biomarker and therapeutic target ...
Amrita Arup Roy +9 more
wiley +1 more source
Bulletin of the Chemical Society of Ethiopia, 2017 In this study, a novel, clean, convenient, appropriate and environmentally benign route to dihydropyrimidinone and thione derivatives has been developed using the reaction between various benzaldehydes, urea or thiourea, and ethyl acetoacetate in the ...
L. Z. Fekri, M. Nikpassand, M. Movaghari
doaj +1 more source
Modified Biginelli Reaction Catalyzed by Cobaltous Chloride Conducted in Microwave [PDF]
, 2016 3, 4- Dihydropyrimidine -2(1H)-Ones were synthesized efficiently using CoCl2.6H2O as catalyst. The reaction was conducted by microwave irradiation without using any solvent.
Singh, Reeta
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Drug Design, Development and Therapy, 2016 Katharigatta N Venugopala,1,2 G B Dharma Rao,3 Subhrajyoti Bhandary,3 Melendhran Pillay,4 Deepak Chopra,3 Bandar E Aldhubiab,1 Mahesh Attimarad,1 Osama Ibrahim Alwassil,1 Sree Harsha,1 Koleka Mlisana4 1Department of Pharmaceutical Sciences, College of ...
Venugopala KN +9 more
doaj
MICROWAVE IRRADIATED GREEN BIGINELLI REACTION†EMPLOYING APPLE, POMEGRANATE AND GRAPE JUICE AS ECO-FRIENDLY REACTION MEDIUM [PDF]
, 2016 Objective: The main objective of this work is to explore the utility of apple, pomegranate and grape juice as an eco-friendly reaction medium for microwave assisted green Biginelli reaction.Methods: A series of Biginelli reactions were carried out in ...
Padan, Simarjit Kaur, Pramanik, Tanay
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Naphthyl‐Based Chalcone Derivatives: A Multifaceted Player in Medicinal Chemistry
ChemistrySelect, Volume 9, Issue 19, May 21, 2024.This review insights the pharmacological activity of naphthyl substituted chalcone derivatives. The anticancer and antibacterial activities were more explored than other activities. The presence of methoxy and naphthyl moiety enhanced the anticancer activity. The antibacterial activity was increased by electron withdrawing groups.
Priyanka Mahesha, Nitinkumar S. Shetty
wiley +1 more source
MICROWAVE ASSISTED GREEN SYNTHESIS OF PHARMACEUTICALLY IMPORTANT DIHYDROPYRIMIDINONES IN FRUIT JUICE MEDIUM [PDF]
, 2015 Objective: The objective of this research project was to perform the green synthesis of a series of Dihydropyrimidinone (DHPM) derivatives which are having immense importance in biological and pharmaceutical science, via microwave assisted Biginelli ...
Maji, Poulami, Pramanik, Tanay
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Update on chiral recognition mechanisms in separation science
Journal of Separation Science, Volume 47, Issue 9-10, May 2024.The stereospecific analysis of chiral molecules is an important issue in many scientific fields. In separation sciences, this is achieved via the formation of transient diastereomeric complexes between a chiral selector and the selectand enantiomers driven by molecular interactions including electrostatic, ion‐dipole, dipole‐dipole, van der Waals or π ...
Gerhard K. E. Scriba
wiley +1 more source
Biochemistry Research International, Volume 2024, Issue 1, 2024.Eg5 is a protein encoded by KIF11 gene and is primarily involved in correct mitotic cell division. It is also involved in nonmitotic processes such as polypeptide synthesis, protein transport, and angiogenesis. The scientific literature sheds light on the ubiquitous functions of KIF11 and its involvement in the onset and progression of different ...
Alessia Ricci +4 more
wiley +1 more source
The antimicrobial evaluation of some biginelli-based azo pyridone dyes [PDF]
, 2023 Heterociklična azo jedinjenja predstavljaju značajnu klasnu organskih sintetskih boja. Pored njihovih izuzetnih svojstava za bojenje, heterociklična azo jedinjenja imaju i biološku aktivnost.
Gazikalović, Ivana +5 more
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