Results 81 to 90 of about 680 (195)

Synthesis And Bioactivity of Dihydropyrimidinone (DHPM) Derivatives

European Chemical Bulletin
Dihydropyrimidinones (DHPMs) is an main type of heterocyclic compounds whih shows biological activities. This review/article focuses on the synthetic strategies employed for the construction of DHPM frameworks and highlights their bioactivity profiles across various pharmacological targets.
Ganesh L. Kirdat, Onkar S. Dhindale, Tushar M. Dalimbkar, Mr. Nikhil A. Mandlik   +3 more
openaire   +2 more sources

Synthesis, identification and application of a new ionic liquid based on 1-vinylimidazole, immobilized on graphene oxide nanosheets

Case Studies in Chemical and Environmental Engineering
In this research, a novel catalyst GO@[PBVIm]HSO4, which is an acidic polymer ionic liquid supported on a graphene oxide substrate, was synthesized. First, (3-aminopropyl) triethoxysilane was attached as a linker to the prepared graphene oxide.
Masoumeh Mirhasani, Reza Sandaroos, Behrooz Maleki, Sahar Peiman   +3 more
doaj   +1 more source

One-pot synthesis of dihydropyrimidinone and polyhydroquinoline derivatives with natural deep eutectic solvents (NADESs): Alternative to toxic organic solvents and environmental eco-friendly

Results in Chemistry
Natural deep eutectic solvents (NADESs) have emerged as a novel class of solvents with properties reminiscent of ionic liquids while offering additional advantages in terms of cost, environmental impact, and synthesis.
Sedigheh Ayazi Jannatabadi, Rahman Hosseinzadeh, Behrooz Maleki   +2 more
doaj   +1 more source

Three-Component Biginelli Cyclocondensation Reaction Using C-Glycosylated Substrates. Preparation of a Collection of Dihydropyrimidinone Glycoconjugates and the Synthesis of C-Glycosylated Monastrol Analogues^†

, 2016
The aldehyde−ketoester−urea cyclocondensation reaction has been revisited using C-glycosylated reagents with the aim of exploring a potential entry to a library of dihydropyrimidinone glycoconjugates.
Alessandro Massi (1528462), Simona Sabbatini (3031668), Alessandro Dondoni (2262598), Valerio Bertolasi (1528465)   +3 more
core   +1 more source

Synthesis and Antioxidant Activity of Novel Biginelli Adducts with Phenolic Fragments

Applied Sciences
In this work, eco-friendly ceric ammonium nitrate (CAN) and ferric chloride hexahydrate catalysts in ethanol/acetonitrile systems were used to efficiently synthesize novel dihydropyrimidinone (-thione) derivatives via the Biginelli reaction. The obtained
Olga V. Snastina, Erik R. Sabitov, Viktoria A. Kuricheva, Vladimir N. Koshelev   +3 more
doaj   +1 more source

Ethyl 6-Methyl-2-oxo-4-{4-[(1-phenyl-1H-1,2,3-triazol-4-yl)methoxy]phenyl}-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Molbank, 2019
The Biginelli reaction is an acid-catalyzed, three-component reaction between an aldehyde, a hydrogen methylene active compound, and urea (or its analogue) and constitutes a rapid and easy synthesis of highly functionalized heterocycles.
Itamar Luís Gonçalves, Gabriel Oliveira de Azambuja, Leonardo Davi, Guilherme Arraché Gonçalves, Luciano Porto Kagami, Gustavo Machado das Neves, João Pedro Silveira, Rômulo Faria Santos Canto, Vera Lucia Eifler-Lima   +8 more
doaj   +1 more source

Targeting RNA with small molecules : dihydropyrimidinone derivatives as novel RNA-binding ligands [PDF]

, 2011
The high functionality and complex three dimensional structure of RNA offers promise for the development of a wide range of RNA-targeting therapeutics.
Satkiewicz, Emily
core  

Combinatorial Synthesis of 2-Thioxo-4-dihydropyrimidinones

, 2016
Combinatorial Synthesis of 2-Thioxo-4 ...
Cheng Leng Lee (3030528), Mui Mui Sim (3030531), Arasu Ganesan (3040221)   +2 more
core   +1 more source

Structural data of DNA binding and molecular docking studies of dihydropyrimidinone transition metal complexes

Data in Brief, 2018
A series of some novel copper complexes derived from Biginelli condensation of DHPHS. The ligand and its transition metal complexes show more antimicrobial activities which was substantiated by molecular docking studies.
P. Vijayakrishnan, S. Arul Antony, D. Velmurugan   +2 more
doaj   +1 more source

Synthesis of 3,4-dihydropyrimidinone compounds and their chiral recognition on polysaccharide chiral stationary phases [PDF]

, 2015
Optimirana su dva reakcijska protokola za sintezu 3,4-dihidropirimidinonskih spojeva (3,4-DHPM) temeljena na primjeni aluminijevog(III) tetrafluorborata heksahidrata i bakrovog(II) besilata tetrahidrata. Neovisno o karakteristikama reaktanata, postignuta
Večenaj, Ivana
core   +3 more sources