Results 81 to 90 of about 611 (196)

Characterization of a Thermally Induced Irreversible Conformational Transition of Amylose Tris(3,5-dimethylphenylcarbamate) Chiral Stationary Phase in Enantioseparation of Dihydropyrimidinone Acid by Quasi-Equilibrated Liquid Chromatography and Solid-State NMR [PDF]

, 2016
A thermally induced irreversible conformational transition of amylose tris(3,5-dimethylphenylcarbamate) (i.e., Chiralpak AD) chiral stationary phase (CSP) in the enantioseparation of dihydropyrimidinone (DHP) acid racemate was studied for the first time ...
Robert M. Wenslow, (2943429), Fang Wang (105926), Thomas M. Dowling (2943426), Ivan Santos (2649235), Jean M. Wyvratt (2943423), Karl T. Mueller (1487707)   +5 more
core   +1 more source

Eg5 and Diseases: From the Well‐Known Role in Cancer to the Less‐Known Activity in Noncancerous Pathological Conditions

Biochemistry Research International, Volume 2024, Issue 1, 2024.
Eg5 is a protein encoded by KIF11 gene and is primarily involved in correct mitotic cell division. It is also involved in nonmitotic processes such as polypeptide synthesis, protein transport, and angiogenesis. The scientific literature sheds light on the ubiquitous functions of KIF11 and its involvement in the onset and progression of different ...
Alessia Ricci, Simone Carradori, Amelia Cataldi, Susi Zara, Anup Pathania   +4 more
wiley   +1 more source

Synthesis and Selective Functionalization of Thiadiazine 1,1-Dioxides with Efficacy in a Model of Huntington’s Disease [PDF]

, 2020
The scope of the acid-mediated 3-component synthesis of thiadiazines was investigated. A selective functionalization of the six-membered heterocyclic core structure was accomplished by sequential alkylations, saponifications, and coupling reactions ...
Linh K. Ngo (8485323), Peter Wipf (134666), Bettina Miller (1550158), Lisa Johnstone (2497069), Christopher J. Rosenker (1986523), Leila Terrab (8485320), Sara Sannino (459131), Nathaniel F. Ware (8485326), Jeffrey L. Brodsky (351261), Andrea Z. Topacio (5117120), Li Zhang (8200)   +10 more
core   +1 more source

Synthesis of some dihydropyrimidinone derivatives and study of their anti-inflammatory activity

Journal of Applied Pharmaceutical Research, 2018
This research revealed that the numbers of available heterocyclic compounds are mainly focused on nitrogen containing compounds, such as quinazolines, indoles, benzimidazole, quinoxalines, coumarins and pyrimidines etc. A mixture of substituted aldehydes
Naresh Podilla, Tirthankar Choudhury
doaj   +1 more source

(6aS*,6bS*,11R*,11aR*)-6-(2-Furylmethyl)-5,12-dioxo-5,6,6a,6b,7,11,11a,12-octahydrofuro[3′,2′:5,6]isoindolo[2,1-a]quinazoline-11-carboxylic acid

Acta Crystallographica Section E, 2011
The title compound, C23H18N2O6, is the product of an intramolecular thermal cycloaddition within 1-malein-2-[(E)-2-(2-furyl)vinyl]-4-oxo-3,4-dihydroquinazoline.
Mykola D. Obushak, Yuri I. Horak, Vladimir P. Zaytsev, Ekaterina L. Motorygina, Fedor I. Zubkov, Victor N. Khrustalev   +5 more
doaj   +1 more source

Isolation of polyphenol compounds from olive waste and inhibition of their derivatives for α-glucosidase and α-amylase [PDF]

, 2019
Olive waste was used as a sustainable resource because it contained a variety of valuable compounds. The polyphenols active fraction from enrichment by microporous resin and extraction with ethyl acetate were analysed by different chromatographic methods.
Zhihong Wang (142713), Mijun Peng (2161246), Sheng Peng (1925566), Chengzhang Wang (520338)   +3 more
core   +1 more source

Molecular Structure and Conformational Dynamics of 3,12-dichloro-5,14-diphenyl-7,9a,16,18a-tetrazadibenzo[\u3cem\u3ea,l\u3c/em\u3e]pentacene-9, 18-dione [PDF]

, 1997
The X-ray study of 3,12-dichloro-5,14-diphenyl-7,9a,16,18a-tetrazadibenzo[a,l]pentacene-9,18-dione (1), a model compound for a novel class of thermostable polyheteroarylenes, polyquinoquinazolones, has been carried out.
Lindeman, Sergey V., Ponomarev, Igor I., Kovalevsky, A. Yu., Volkova, Yu. A., Ronova, I. A., Shishkin, O. V.   +5 more
core   +1 more source

Synthesis, identification and application of a new ionic liquid based on 1-vinylimidazole, immobilized on graphene oxide nanosheets

Case Studies in Chemical and Environmental Engineering
In this research, a novel catalyst GO@[PBVIm]HSO4, which is an acidic polymer ionic liquid supported on a graphene oxide substrate, was synthesized. First, (3-aminopropyl) triethoxysilane was attached as a linker to the prepared graphene oxide.
Masoumeh Mirhasani, Reza Sandaroos, Behrooz Maleki, Sahar Peiman   +3 more
doaj   +1 more source

One-pot synthesis of dihydropyrimidinone and polyhydroquinoline derivatives with natural deep eutectic solvents (NADESs): Alternative to toxic organic solvents and environmental eco-friendly

Results in Chemistry
Natural deep eutectic solvents (NADESs) have emerged as a novel class of solvents with properties reminiscent of ionic liquids while offering additional advantages in terms of cost, environmental impact, and synthesis.
Sedigheh Ayazi Jannatabadi, Rahman Hosseinzadeh, Behrooz Maleki   +2 more
doaj   +1 more source

Ethyl 6-Methyl-2-oxo-4-{4-[(1-phenyl-1H-1,2,3-triazol-4-yl)methoxy]phenyl}-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Molbank, 2019
The Biginelli reaction is an acid-catalyzed, three-component reaction between an aldehyde, a hydrogen methylene active compound, and urea (or its analogue) and constitutes a rapid and easy synthesis of highly functionalized heterocycles.
Itamar Luís Gonçalves, Gabriel Oliveira de Azambuja, Leonardo Davi, Guilherme Arraché Gonçalves, Luciano Porto Kagami, Gustavo Machado das Neves, João Pedro Silveira, Rômulo Faria Santos Canto, Vera Lucia Eifler-Lima   +8 more
doaj   +1 more source