Results 71 to 80 of about 392 (169)

Synthesis and Antioxidant Activity of Novel Biginelli Adducts with Phenolic Fragments

Applied Sciences
In this work, eco-friendly ceric ammonium nitrate (CAN) and ferric chloride hexahydrate catalysts in ethanol/acetonitrile systems were used to efficiently synthesize novel dihydropyrimidinone (-thione) derivatives via the Biginelli reaction. The obtained
Olga V. Snastina, Erik R. Sabitov, Viktoria A. Kuricheva, Vladimir N. Koshelev   +3 more
doaj   +1 more source

Structural data of DNA binding and molecular docking studies of dihydropyrimidinone transition metal complexes

Data in Brief, 2018
A series of some novel copper complexes derived from Biginelli condensation of DHPHS. The ligand and its transition metal complexes show more antimicrobial activities which was substantiated by molecular docking studies.
P. Vijayakrishnan, S. Arul Antony, D. Velmurugan   +2 more
doaj   +1 more source

Copper salt of a DABCO-based molten salt: a high-performance catalyst in the one-pot synthesis of 3,4-dihydropyrimidine and polyhydroquinoline derivatives. [PDF]

RSC Adv, 2023
Fekrat N, Mazloumi M, Shirini F.
europepmc   +1 more source

Bioactivity of dihydropyrimidinone derivatives as inhibitors of cyclooxygenase-2 (COX-2): an in silico approach. [PDF]

RSC Adv, 2023
Haq KU, Sa'adah NL, Siswanto I, Suwito H.   +3 more
europepmc   +1 more source

Green and Efficient Synthesis of Dihydropyrimidinone Analogues via Hpa-Clay Catalyzed Biginelli Reaction

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry
This study introduces an environmentally sustainable approach for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones (DHPMs), via the Biginelli reaction. A heterogeneous catalyst, Heteropolyacid-Clay (HPA-Clay), is developed by immobilizing H5PV2W10O40 on ...
Nuzhat Rehman, Ayaz Mahmood Dar, Raja Feroz Ahmad Haji, Sharief-ud-din Khan, Deepak Pareek, Saleem Farooq, Bashir Ahmad Dar   +6 more
doaj   +1 more source

Exploring the binding dynamics of anticancer Dihydropyrimidinone derivatives with Serum Albumin: A multispectral approach

Chemical Physics Impact
In this work, we have investigated the synthesis and characterization of two novel anticancer agents, 5-acetyl-6-methyl-4-phenyl-3,4-dihydropyrimidin-2(1H)-one (L1) and 2-Acetyl-4-(3,4-dimethoxy-phenyl)-6-methyl-3,4-dihydro-1H-pyrimidin-2-one (L2 ...
Chandraprakash Gond, Shivani Daksh, Akanksha Mishra, Nikhil Kumar, Anupama Datta, Anjani Kumar Tiwari   +5 more
doaj   +1 more source

Benchtop ¹⁹F Nuclear Magnetic Resonance (NMR) Spectroscopy Provides Mechanistic Insight into the Biginelli Condensation toward the Chemical Synthesis of Novel Trifluorinated Dihydro- and Tetrahydropyrimidinones as Antiproliferative Agents. [PDF]

ACS Omega, 2023
Chen R, Singh P, Su S, Kocalar S, Wang X, Mandava N, Venkatesan S, Ferguson A, Rao A, Le E, Rojas C, Njoo E.   +11 more
europepmc   +1 more source

Sustainable Biginelli chemistry: Indian contributions to green multicomponent synthesis

Discover Chemistry
The Biginelli Reaction is a one-pot acid-catalysed cyclo-condensation procedure that combines urea, β-ketoester, and aromatic aldehydes to create functionalised DHPMs. For more than a century, this three-component reaction has been recognised as a method
Rajni, Sahil, Neera Raghav, Anjaneyulu Bendi, G. B. Dharma Rao   +4 more
doaj   +1 more source

Hybrid Dihydropyrimidinones Targeting AKT Signaling: Antitumor Activity in Hormone-Dependent 2D and 3D Cancer Models. [PDF]

Pharmaceutics
Tejada AH, Santos SJ, Lobo GT, Ariwoola AA, Bezerra AJA, Stringhetta GR, Gomes INF, da Silva LS, Reis RMV, Preto DD, Russowsky D, Silva-Oliveira RJ.   +11 more
europepmc   +1 more source

Corrigendum to "Synthesis, characterization and biological profile of some new dihydropyrimidinone derivaties" [Heliyon Volume 11, Issue 1, 15 January 2025, e41152]. [PDF]

Heliyon
Kanwal M, Nadeem H, Malik S, Maqsood S.
europepmc   +1 more source