Synthesis and Antioxidant Activity of Novel Biginelli Adducts with Phenolic Fragments
Applied SciencesIn this work, eco-friendly ceric ammonium nitrate (CAN) and ferric chloride hexahydrate catalysts in ethanol/acetonitrile systems were used to efficiently synthesize novel dihydropyrimidinone (-thione) derivatives via the Biginelli reaction. The obtained
Olga V. Snastina +3 more
doaj +1 more source
Data in Brief, 2018 A series of some novel copper complexes derived from Biginelli condensation of DHPHS. The ligand and its transition metal complexes show more antimicrobial activities which was substantiated by molecular docking studies.
P. Vijayakrishnan +2 more
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Microwave-assisted multicomponent reaction for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones and their corresponding 2(1H)-thiones using lanthanum oxide as a catalyst under solvent-free conditions [PDF]
, 2016 An efficient synthesis of 3,4-dihydropyrimidinone derivatives using lanthanum oxide as a catalyst, from aldehydes, β-keto ester and urea/thiourea without solvent under the irradiation of microwave is described.
Kuraitheerthakumaran, A. +5 more
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Targeting RNA with small molecules : dihydropyrimidinone derivatives as novel RNA-binding ligands [PDF]
, 2011 The high functionality and complex three dimensional structure of RNA offers promise for the development of a wide range of RNA-targeting therapeutics.
Satkiewicz, Emily
core
Epidemiological studies of multiresistant bacteria in the city of Pelotas and susceptibility to dihydropyrimidinone [PDF]
, 2019 Bacterial resistance to antibiotics is a global public health problem. The indiscriminate use of antibiotics has accelerated this process, causing increased morbidity and mortality of healthcare-related infections. The increasing inefficiency of existing
Jara, Marisa Castro
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Potent, Selective and Orally Bioavailable Dihydropyrimidine Inhibitors of Rho Kinase (ROCK1) as Potential Therapeutic Agents for Cardiovascular Diseases [PDF]
, 2016 Recent studies using known Rho-associated kinase isoform 1 (ROCK1) inhibitors along with cellular and molecular biology data have revealed a pivotal role of this enzyme in many aspects of cardiovascular function.
Dennis Lee (2409307) +19 more
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Solvent-Free Synthesis of Dihydropyrimidinone by Using Molecular Iodine as Catalyst [PDF]
Dihydropyrimidinone with diverse pharmacological activities can be obtained through the multicomponent of Biginelli reactions by heating aldehyde, ethyl acetoacetate and urea/thiourea in ethanol with the addition of hydrochloric acid.
Fadlan, Arif +2 more
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Synthesis of 3,4-dihydropyrimidinone compounds and their chiral recognition on polysaccharide chiral stationary phases [PDF]
, 2015 Optimirana su dva reakcijska protokola za sintezu 3,4-dihidropirimidinonskih spojeva (3,4-DHPM) temeljena na primjeni aluminijevog(III) tetrafluorborata heksahidrata i bakrovog(II) besilata tetrahidrata. Neovisno o karakteristikama reaktanata, postignuta
Večenaj, Ivana
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Copper salt of a DABCO-based molten salt: a high-performance catalyst in the one-pot synthesis of 3,4-dihydropyrimidine and polyhydroquinoline derivatives. [PDF]
RSC Adv, 2023 Fekrat N, Mazloumi M, Shirini F.
europepmc +1 more source
Bioactivity of dihydropyrimidinone derivatives as inhibitors of cyclooxygenase-2 (COX-2): an in silico approach. [PDF]
RSC Adv, 2023 Haq KU +3 more
europepmc +1 more source