Results 81 to 90 of about 843 (203)

Microwave assisted solvent-free synthesis of dihydropyrimidinones by Biginelli reaction over Si-MCM-41 supported FeCl₃ catalyst

, 2003
Among the Si-MCM-41 or montmorillonite K 10 clay supported ZnCl2, AlCl3, GaCl3, InCl3 and FeCl3 catalysts, FeCl3/Si-MCM-41 shows best performance for the microwave-assisted synthesis of dihydropyrimidinones by the Biginelli reaction involving ...
Tillu, V. H., Wakharkar, R. D., Choudhary, V. R., Borate, H. B., Narkhede, V. S.   +4 more
core   +1 more source

Eg5 and Diseases: From the Well‐Known Role in Cancer to the Less‐Known Activity in Noncancerous Pathological Conditions

Biochemistry Research International, Volume 2024, Issue 1, 2024.
Eg5 is a protein encoded by KIF11 gene and is primarily involved in correct mitotic cell division. It is also involved in nonmitotic processes such as polypeptide synthesis, protein transport, and angiogenesis. The scientific literature sheds light on the ubiquitous functions of KIF11 and its involvement in the onset and progression of different ...
Alessia Ricci, Simone Carradori, Amelia Cataldi, Susi Zara, Anup Pathania   +4 more
wiley   +1 more source

Synthesis And Bioactivity of Dihydropyrimidinone (DHPM) Derivatives

European Chemical Bulletin
Dihydropyrimidinones (DHPMs) is an main type of heterocyclic compounds whih shows biological activities. This review/article focuses on the synthetic strategies employed for the construction of DHPM frameworks and highlights their bioactivity profiles across various pharmacological targets.
Ganesh L. Kirdat, Onkar S. Dhindale, Tushar M. Dalimbkar, Mr. Nikhil A. Mandlik   +3 more
openaire   +2 more sources

PEG-assisted solvent and catalyst free synthesis of 3,4-dihydropyrimidinones under mild reaction conditions

, 2010
PEG-assisted solvent and catalyst free synthesis of 3,4- dihydropyrimidinones under mild and neutral reaction conditions is ...
Singhal,Sweety, Jain, Suman L, Sain,Bir
core  

One-Pot Synthesis of Dihydropyrimidinones/Thiones Catalyzed by White Marble a Metamorphic Rock an Efficient and Reusable Catalyst for the Biginelli Reaction

, 2018
International audienceIn this work, we report a simple, efficient and green protocol for the synthesis of dihydropyrimidinones/thiones (products of Biginelli reaction) by the use of white marble as an effective heterogeneous catalyst.
H. Chaair, Oudadesse, H., Chaair, H., K. El Mejdoubi, B. Sallek, El Mejdoubi, K., Sallek, B., Cherkaoui, H., H. Oudadesse, H. Cherkaoui   +9 more
core   +1 more source

Efficient Oxidative Dehydrogenation of Dihydropyrimidinones and Thiocyanation of Aromatic Compounds Using 1,1,2,2-Tetrahydroperoxy-1,2-diphenylethane as the Oxidant

, 2019
A new, efficient and mild approach for the oxidative dehydrogenation of dihydropyrimidinones and thiocyanation of aromatic compounds using 1,1,2,2-tetrahydroperoxy-1,2-diphenylethane (THPDPE) as a terminal oxidant was developed.
Naserifar, Shirin, Azizi, Amir,, Khosravi, Kaveh, Khosravi, Kaveh,, Naserifar, Shirin,, Azizi, Amir   +5 more
core   +1 more source

Copper(II) Sulfamate: An Efficient Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidine-2(1H)-ones and thiones

Molecules, 2009
A simple, efficient procedure for the one-pot Biginelli condensation reaction of aldehydes, β-ketoesters and urea or thiourea employing copper(II) sulfamate as a novel catalyst is described.
Ji-De Wang, Chen-Jiang Liu
doaj   +1 more source

Efficient Synthesis of 3,4-Dihydropyrimidin-2-ones in Low Melting Tartaric Acid – Urea Mixtures [PDF]

, 2011
A general, efficient and green method for the synthesis of dihydropyrimidinones is described under mild conditions employing low melting mixtures of L-(+)-tartaric acid and urea derivatives as a novel reaction medium.
Burkhard Koenig, Koenig, Burkhard, Gore, S., Baskaran, S., Gore, Sangram, König, Burkhard, Sangram Gore, Sundarababu Baskaran, Baskaran, Sundarababu   +8 more
core   +1 more source

Nano-ZrO2-Catalyzed Biginelli Reaction and the Synthesis of Bioactive Dihydropyrimidinones That Targets PPAR-γ in Human Breast Cancer Cells

, 2023
Bioactive dihydropyrimidinones (DHPs) were designed and synthesized by a multicomponent Biginelli reaction. The reaction was catalyzed by the polarized surface of nano-zirconium dioxide with partial positive charge of 0.52e at the Zr center and a ...
Mahendra Madegowda, Bhanuprakash C. Narasimhachar, Basappa Basappa, Zhang Xi, Kashifa Fazl-Ur-Rahman, Ganga Periyasamy, Suresha N. Deveshegowda, Omantheswara Nagaraja, Peter E. Lobie, Vijay Pandey, Ji-Rui Yang, Gautam Sethi, Shobith Rangappa   +12 more
core   +1 more source

Synthèse et évaluation de l'activité biologique des dérivés 3,4-dihydropyrimidinones-5-carbohydrazides [PDF]

, 2020
52 f. ; 30 cm + (CD Rom)Les composés DHPMs-hydrazides sont une classe de composés thérapeutiquement importante. Ils possèdent diverses activités biologiques telles que anticancéreux, antimicrobien, antihypertenseur, anti-inflammatoire, antituberculeux ...
Kebir, Samia, Menguelti, Dyhia
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