Results 71 to 80 of about 1,311 (206)

Self‐Healing Hydrogel Dressing with Solubilized Flavonoids for Whole Layer Regeneration of Diabetic Wound

Advanced Healthcare Materials, Volume 14, Issue 11, April 25, 2025.
High glucose‐ and acid‐responsive hydrogel with dynamic covalent bond solubilized with flavonoids (Gel‐Flavonoids) is designed for diabetic wound healing. The Gel‐Flavonoids adapt to irregular wound shapes and release antioxidants in high‐glucose environments, effectively reducing reactive oxygen species.
Qiang Zeng, Sa Du, Rui Yuan, Yuan Zeng, Xuefen Li, Yu‐Wei Wu, Ke Chen, Lei Tao, Zhihui Tang, Xuliang Deng   +9 more
wiley   +1 more source

The Confluence of Nanotechnology and Heat Shock Protein 70 in Pioneering Glioblastoma Multiforme Therapy: Forging Pathways Towards Precision Targeting and Transformation

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2025, Issue 1, 2025.
Heat‐shock protein 70 (HSP70) and nanotechnology have emerged as promising avenues in glioblastoma multiforme (GBM) therapy, addressing the critical challenges posed by its aggressive nature and therapeutic resistance. HSP70’s dual role in cellular stress response and tumour survival emphasises its potential as both a biomarker and therapeutic target ...
Amrita Arup Roy, Abhijeet Pandey, Namdev Dhas, Manasa Manjunath Hegde, Harendra S. Parekh, Sai Balaji Andugulapati, Krishnadas Nandakumar, Bola Sadashiva Satish Rao, Srinivas Mutalik, Farshad Mirzavi   +9 more
wiley   +1 more source

ANÁLISE CONFORMACIONAL DE COMPOSTOS DE BIGINELLI COM ATIVIDADE ANTINEOPLÁSICA

Eclética Química, 2018
Dihydropyrimidinones, such as monastrol and analogues, are heterocycles with known antineoplastic activity. Conformational  analysis represents an important preliminary step in structure-activity correlation studies. Herein we describe the conformational
Marcelo Volpatto Marques, Denis Russowsky, L. M. A. Fontoura   +2 more
doaj   +1 more source

Synthesis and Physicochemical Studies of some Molecules of Meducinal Interest [PDF]

, 2010
Not ...
Gajera, Rave V.
core  

Human transforming growth factor β type I receptor in complex with kinase inhibitor SB505124

Acta Crystallographica Section F, Volume 80, Issue 11, Page 314-319, November 2024.
This study presents the crystal structure of transforming growth factor β type I receptor (TβR1) in complex with SB505124, highlighting the specific contacts that SB505124 makes with TβR1 and comparing these interactions with those of SB431542.The crystal structure of the intracellular domain of transforming growth factor β type I receptor (TβR1) in ...
Jhon A. Rodriguez Buitrago, Maréne Landström, Magnus Wolf-Watz   +2 more
wiley   +1 more source

Halometallate ionic liquids – revisited [PDF]

, 2014
Ionic liquids with chlorometallate anions may not have been the first ionic liquids, however, it was their development that lead to the recognition that ionic liquids are a distinct, and useful, class of (functional) materials.
Estager, J., Holbrey, J. D., Swadźba-Kwaśny, Malgorzata   +2 more
core   +1 more source

Naphthyl‐Based Chalcone Derivatives: A Multifaceted Player in Medicinal Chemistry

ChemistrySelect, Volume 9, Issue 19, May 21, 2024.
This review insights the pharmacological activity of naphthyl substituted chalcone derivatives. The anticancer and antibacterial activities were more explored than other activities. The presence of methoxy and naphthyl moiety enhanced the anticancer activity. The antibacterial activity was increased by electron withdrawing groups.
Priyanka Mahesha, Nitinkumar S. Shetty
wiley   +1 more source

Al(NO3)3 · 9H2O: An Efficient Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones Both under Reflux or Solvent-Free Conditions

Journal of Chemistry, 2013
Al(NO3)3 · 9H2O efficiently catalyzes the three-component Biginelli reaction between an aldehyde, a β-dicarbonyl compound, and urea or thiourea in refluxing ethanol and solvent-free (SF) conditions to afford the corresponding dihydropyrimidinones in high
Eskandar Kolvari, Maryam Mirzaeeyan
doaj   +1 more source

Update on chiral recognition mechanisms in separation science

Journal of Separation Science, Volume 47, Issue 9-10, May 2024.
The stereospecific analysis of chiral molecules is an important issue in many scientific fields. In separation sciences, this is achieved via the formation of transient diastereomeric complexes between a chiral selector and the selectand enantiomers driven by molecular interactions including electrostatic, ion‐dipole, dipole‐dipole, van der Waals or π ...
Gerhard K. E. Scriba
wiley   +1 more source

Eg5 and Diseases: From the Well‐Known Role in Cancer to the Less‐Known Activity in Noncancerous Pathological Conditions

Biochemistry Research International, Volume 2024, Issue 1, 2024.
Eg5 is a protein encoded by KIF11 gene and is primarily involved in correct mitotic cell division. It is also involved in nonmitotic processes such as polypeptide synthesis, protein transport, and angiogenesis. The scientific literature sheds light on the ubiquitous functions of KIF11 and its involvement in the onset and progression of different ...
Alessia Ricci, Simone Carradori, Amelia Cataldi, Susi Zara, Anup Pathania   +4 more
wiley   +1 more source