Results 11 to 20 of about 5,442 (212)
A New Diketopiperazine, Cyclo-(4-S-hydroxy-R-proline-R-isoleucine), from an Australian Specimen of the Sponge Stelletta sp. [PDF]
Marine Drugs, 2011 While investigating the cytotoxic activity of the methanol extract of an Australian marine sponge Stelletta sp. (Demospongiae), a new diketopiperazine, cyclo-(4-S-hydroxy-R-proline-R-isoleucine) (1), was isolated together with the known bengamides; A (2),
Dianne M. Tapiolas +6 more
doaj +2 more sources
Marine Drugs, 2019 While several marine natural products bearing the 2,5-diketopiperazine ring have been reported to date, the unique chemistry of dimeric frameworks appears to remain neglected.
Nelson G. M. Gomes +3 more
doaj +2 more sources
(E)-N-(3-(5-(3-Acetamidopropyl)-3,6-dioxopiperazin-2-yl)propyl)-5-hydroxy-3-methylpent-2-enamide
Molbank, 2023 The Atacama Desert is an unexplored habitat with interesting possibilities for natural product chemistry due to the adaptations employed by microorganisms to survive the extreme salinity and high UV radiation present.
Gagan Preet +5 more
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Marine Drugs, 2020 The geographic position, highly fluctuating sea temperatures and hypersalinity make Persian Gulf an extreme environment. Although this unique environment has high biodiversity dominated by invertebrates, its potential in marine biodiscovery has largely ...
Reza Mohsenian Kouchaksaraee +4 more
doaj +1 more source
Characterisation of Cooked Cheese Flavour: Non-Volatile Components
Foods, 2023 This work examined the role of selected non-volatile compounds in cooked cheese flavour, both as tastants and as precursors of aroma generation in the Maillard reaction.
Rosa C. Sullivan +5 more
doaj +1 more source
Molecules, 2021 Phosphodiesterase 5 (PDE5) is one of the most extensively studied phosphodiesterases that is highly specific for cyclic-GMP hydrolysis. PDE5 became a target for drug development based on its efficacy for treatment of erectile dysfunction.
Adam Mieczkowski +12 more
doaj +1 more source
α-Glucosidase Inhibitors from Two Mangrove-Derived Actinomycetes
Molecules, 2023 α-Glucosidase (AGS) inhibitors have been regarded as an ideal target for the management of type 2 diabetes mellitus (T2DM) since they can maintain an acceptable blood glucose level by delaying the digestion of carbohydrates and diminishing the absorption
Xuejun Lu +11 more
doaj +1 more source
Applied Sciences, 2021 Chemical investigations of Aquimarina sp. MC085, which suppressed TGF-β-induced epithelial–mesenchymal transition (EMT) in A549 human lung cancer cells, led to the isolation of compounds 1–3.
Myong Jin Lee +7 more
doaj +1 more source
Marine Drugs, 2021 The Persian Gulf is a unique and biologically diverse marine environment dominated by invertebrates. In continuation of our research interest in the chemistry and biological activity of marine sponges from the Persian Gulf, we selected the excavating ...
Reza Mohsenian Kouchaksaraee +4 more
doaj +1 more source
, 2019 An enantioselective synthesis of iso-, isothio-, and isoselenohydantoin and diketopiperazine-fused tetrahydroisoquinolines from l-Dopa was reported. The route consists of an Pictet–Spengler reaction of (S)-2-amino-3-(3,4-dimethoxyphenyl)propanoates with
Jia-Yun Haung (6426347) +4 more
core +5 more sources