Results 21 to 30 of about 5,442 (212)
Synthesis of the diketopiperazine dipodazine
, 2002 The diketopiperazine derivative dipodazine (1), isolated from Penicillium dipodomyis, has been synthesized via a stereoselective aldol condensation from N-protected indole-3-carboxaldehyde and 1,4-diacetyl-2,5-piperazinedione (3) in the presence of ...
Janosik, T, Bergman, Jan,, Johnson, A L
core +4 more sources
Maculosin, a non-toxic antioxidant compound isolated from Streptomyces sp. KTM18
Pharmaceutical Biology, 2021 Context Streptomyces species are prolific sources of bioactive secondary metabolites known especially for their antimicrobial and anticancer activities.
Babita Paudel +8 more
doaj +1 more source
Molecules, 2023 Ochratoxin A is historically the most notable secondary metabolite of Aspergillus ochraceus on account of its toxicity to animals and fish. Currently, over 150 compounds of diverse structure and biosynthesis is a challenge to predict the array for any ...
Peter Mantle +2 more
doaj +1 more source
Diels–Alder Cycloaddition of Chiral Nonracemic 2,5-Diketopiperazine Dienes
, 2016 Preparation of a chiral, nonracemic 2,5-diketopiperazine diene has enabled the investigation of intermolecular hetero-Diels–Alder cycloadditions.
Jonathan R. Scheerer (1676254) +3 more
core +2 more sources
Molecules, 2019 The glyoxylate cycle is a sequence of anaplerotic reactions catalyzed by the key enzymes isocitrate lyase (ICL) and malate synthase, and plays an important role in the pathogenesis of microorganisms during infection.
Heegyu Kim +3 more
doaj +1 more source
Structure and Function of NzeB, a Versatile C–C and C–N Bond Forming Diketopiperazine Dimerase [PDF]
, 2020 This report details the discovery and characterization of a versatile bacterial cytochrome P450, NzeB, which catalyzes the dimerization of diketopiperazines via enzymatic C–H functionalization. This includes the first high-resolution crystal structure of
Sean A., Newmister +10 more
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Marine Drugs, 2023 Two new quinazolinone diketopiperazine alkaloids, including versicomide E (2) and cottoquinazoline H (4), together with ten known compounds (1, 3, and 5–12) were isolated and identified from Aspergillus versicolor AS-212, an endozoic fungus associated ...
Yu-Liang Dong +5 more
doaj +1 more source
Hydrobiology, 2023 Streptomyces sp. N11-50 was isolated from deep-sea water and found to produce diketopiperazine (DKP) compounds such as albonoursin and cyclo(Phe-Leu).
Hisayuki Komaki +2 more
doaj +1 more source
Modeling the fragmentation of 2,5-diketopiperazine ions [PDF]
, 2021 Cyclic dipeptides, often found in nature, are formed by linking amino-terminus of a linear dipeptide to it carboxyl - terminus by amide bond. All of them are derivatives of 2,5-diketopiperazine (DKP) or cyclo-Diglycine with the molecular formula C4H6N2O2
Petrov, A. +4 more
core +1 more source
A mechanochemical approach to access the proline–proline diketopiperazine framework
Beilstein Journal of Organic Chemistry, 2017 Ball milling was exploited to prepare a substituted proline building block by mechanochemical nucleophilic substitution. Subsequently, the mechanocoupling of hindered proline amino acid derivatives was developed to provide proline–proline dipeptides ...
Nicolas Pétry +9 more
doaj +1 more source