Results 71 to 80 of about 5,247 (209)

Positive Regulation of Spoilage Potential and Biofilm Formation in Shewanella baltica OS155 via Quorum Sensing System Composed of DKP and Orphan LuxRs

Frontiers in Microbiology, 2019
The spoilage potential and biofilm formation of Shewanella baltica are reported to be regulated by Quorum sensing (QS) system from the phenotype point of view, but the specific mechanism is not fully understood.
Yanbo Wang, Yanbo Wang, Feifei Wang, Chong Wang, Xiuting Li, Linglin Fu, Linglin Fu   +6 more
doaj   +1 more source

In vivo characterization of the activities of novel cyclodipeptide oxidases: new tools for increasing chemical diversity of bioproduced 2,5-diketopiperazines in Escherichia coli

Microbial Cell Factories, 2020
Background Cyclodipeptide oxidases (CDOs) are enzymes involved in the biosynthesis of 2,5-diketopiperazines, a class of naturally occurring compounds with a large range of pharmaceutical activities. CDOs belong to cyclodipeptide synthase (CDPS)-dependent
Fabien Le Chevalier, Isabelle Correia, Lucrèce Matheron, Morgan Babin, Mireille Moutiez, Nicolas Canu, Muriel Gondry, Olivier Lequin, Pascal Belin   +8 more
doaj   +1 more source

Beitrag zur Stereochemie der 2, 5-Diketopiperazine [PDF]

Berichte der deutschen chemischen Gesellschaft, 1906
Fur die Diketopiperazine von der allgemeinen Formel Open image in new window mit zwei gleichen Substituenten last die Theorie bekanntlich wie bei der Weinsaure vier Formen voraussehen, namlich zwei optisch active Antipoden nebst dem entsprechenden Racemkorper und eine inactive, nicht spaltbare Mesoverbindung, in welcher die Substituenten trans-Stellung
Fischer, Emil, Raske, Karl
openaire   +2 more sources

Evaluation of multivalency as an organization principle for the efficient synthesis of doubly and triply threaded amide rotaxanes [PDF]

, 2014
Mono-, di- and trivalent pseudorotaxanes with tetralactam macrocycle hosts and axles containing diamide binding stations as the guests have been synthesised.
Kaufmann, Lena, Mäkelä, Toni, Rissanen, Kari, Schalley, Christoph A., Schröder, Hendrik V., Springer, Andreas, Traulsen, Nora L.   +6 more
core   +1 more source

Advances in the Development of Lipid Nanoparticles for mRNA Delivery

Small Structures, Volume 7, Issue 2, February 2026.
This review provides an integrated overview of mRNA–lipid nanoparticle (LNP) design, including lipid composition, scalable manufacturing, and structure–activity relationships. We highlight strategies for targeted delivery, physicochemical tuning, and high‐throughput screening such as DNA barcoding.
Xing Wang, Letao Xu, Zhenwei Lan, Yue Hui, Yun Liu, Guangze Yang, Chun‐Xia Zhao   +6 more
wiley   +1 more source

Antifungal Metabolites from Marine-Derived Streptomyces sp. AMA49 against Pyricularia oryzae

Journal of Pure and Applied Microbiology, 2019
Marine-derived actinobacteria are considered as potential sources of bioactive metabolites including antifungal substances. Fifteen out of 155 marine-derived actinobacteria exhibited strong antifungal activity against the rice blast fungus Pyricularia ...
Jirayu Buatong, Vatcharin Rukachaisirikul, Suthinee Sangkanu, Frank Surup, Souwalak Phongpaichit   +4 more
doaj   +1 more source

Microbial Chemical Diversity and Cytotoxic Potential From Brazilian Ferruginous Caves: A Pioneering Metabolomic Survey

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Cave microbiomes represent a rich yet understudied source of chemical diversity with biotechnological properties. Microorganisms in these environments thrive under extreme conditions such as darkness, oligotrophy, and high concentrations of inorganic matter like iron ore.
Natália Naomi Kato, Aline Figueiredo Cardoso, Bianca Del Bianco Sahm, Letícia Veras Costa‐Lotufo, José Augusto Pires Bitencourt, Norberto Peporine Lopes   +5 more
wiley   +1 more source

Enzyme‐Responsive Porous Scaffolds by Electrospinning Polyalanine

Macromolecular Chemistry and Physics, Volume 227, Issue 2, 29 January 2026.
Sustainably synthesized polyalanine (PAla) was co‐electrospun with poly(ε‐caprolactone) (PCL) to create robust nanofibrous scaffolds. The inclusion of PAla dramatically increased the maximum tensile stress by 399%. These ‘smart’ scaffolds demonstrated selective degradation in the presence of human neutrophil elastase (HNE), pioneering mechanically ...
Patrick A. Wall, Charles Brooker, Giuseppe Tronci, Paul D. Thornton   +3 more
wiley   +1 more source

Emestrin‐Type Epidithiodiketopiperazines Inhibited Gasdermin D‐Mediated Pyroptosis via Caspase‐3/7 Activation

MedComm, Volume 7, Issue 1, January 2026.
This study demonstrates that emestrin‐type ETPs suppress GSDMD‐mediated pyroptosis through caspase‐3/7 activation, thereby attenuating inflammatory responses and conferring protection against sepsis. In THP‐1 macrophages, ETPs significantly reduced pyroptosis and secretion of the proinflammatory cytokines IL‐1β and IL‐18.
Bingchuan Geng, Shuang Lin, Wai Yen Yim, Weiguang Sun, Xiaotian Zhang, Cao Ma, Zhiwen Zhang, Quan Guo, Jie Gao, Hanxiao Zeng, Qingyi Tong, Yixuan Wang, Zhengfeng Fan, Jincheng Hou, Muwei Li, Yonghui Zhang, Zhengxi Hu   +16 more
wiley   +1 more source

Quorum sensing: An imperative longevity weapon in bacteria [PDF]

, 2018
Bacterial cells exhibit a complex pattern of co-operative behaviour as shown by their capacity to communicate amongst each other. Quorum sensing (QS) is a generic term used for bacterial cell-to-cell communication which secures survival of its species ...
Lahiri, Chandrajit *, Pawar, Shrikant
core   +1 more source