Results 101 to 110 of about 100,813 (283)
“Too Much of a Good Thing”: Inadvertent Acetaminophen Overdose in a Low‐Weight Elderly Patient
General pharmacokinetic pathway of acetaminophen metabolism and respective oxidation, conjugation, and metabolic toxic and non‐toxic production steps. ABSTRACT Commonly used for its analgesic and anti‐pyretic properties, acetaminophen (“Tylenol”) is effective in managing generalized pain.
Theodore Joseph Miller IV +4 more
wiley +1 more source
İletişim sürecinde kullanılan dil sistemlerinden en yaygın olanlarından bir biçiminin de yazılı dil olduğu bir gerçektir. Yazılı dil özellikle basının başlıca iletişim aracıdır. Basın bu iletişim aracını olağan üstü bir maharetle kullanarak okuyucuları dilediği yönde manipüle edebilmektedir.
openaire +4 more sources
Salivary metabolomics offers a noninvasive and effective approach for early disease detection and monitoring. Salivary metabolites reflect systemic metabolism, inflammation, and external factors such as diet and stress. Advance in bioinformatics and machine learning facilitates the identification of metabolic biomarkers with high diagnostic accuracy ...
Xinyuan Zhao +8 more
wiley +1 more source
Gunumuzde uluslararasi alanda populerligi ve izleyicisi en fazla olan spor dallarinin basinda gelen futbol hem gorsel hem de yazili basinda genis bir yer tutmaktadir. Bu arastirmada futbol ile ilgili olarak yazili basinda cikan makalelere yer verilmistir.
openaire +3 more sources
The study investigates the sedative potential of naringenin (NAR) through in vivo and in silico approaches. NAR significantly enhances sleep duration and reduces latency in mice, especially when combined with diazepam. Molecular docking shows strong binding to GABAA receptors, suggesting a GABAergic mechanism.
Dipu Bishwas +8 more
wiley +1 more source
Severe drug-induced liver injury associated with prolonged use of Linezolid [PDF]
This study aims to describe a patient developing concomitant severe liver failure and lactic acidosis after long-term treatment with linezolid. A 55-year-old Caucasian woman developed concomitant severe liver failure and lactic acidosis after a treatment
Benoit, Dominique +7 more
core +1 more source
Predicting Systemic and Liver Bosentan Exposure Using Physiologically‐Based Pharmacokinetic Modeling
ABSTRACT Bosentan is the first approved oral medication for pulmonary arterial hypertension, yet the black‐box warning on its labeling implies a substantial risk of liver injury associated with bosentan exposure. The risk assessment of bosentan‐induced liver injury requires a thorough understanding of the underlying mechanisms, for which there is ...
Miao‐Chan Huang +6 more
wiley +1 more source
Intravital Multiphoton Microscopy with Fluorescent Bile Salts in Rats as an In Vivo Biomarker for Hepatobiliary Transport Inhibition [PDF]
The bile salt export pump (BSEP) is expressed at the canalicular domain of hepatocytes, where it mediates the elimination of monovalent bile salts into the bile.
Chen, Yuan +5 more
core +1 more source
Türk Dili ve Kültürünün Alman Dili ve Kültürüne Etkileri
OZET HumOOldt'un tabiriyle canli bir organizma olan bir dile baska bir dilden farlcli alanlardan ve degisik yollardan kelimeler geciyor. Bu yabanci kelimeler gectiAi dile ya yerlesiyor veya belli bir sure kullanilip kayboluyorlar. K.ell:me hazinesinden bir dilin hangi dillerden ve kUltUrlerden etkilendigi.
openaire +3 more sources
Incidence of drug-induced liver injury in medical inpatients [PDF]
Objectives: Drug-induced liver injury (DILI) is a common concern. However, data on DILI epidemiology in inpatients are sparse. Methods: To investigate the incidence of DILI, we screened all patients in the pharmacoepidemiological inpatient database ...
Cavallaro, Marzia +6 more
core

