Results 21 to 30 of about 13,535 (197)

A Computational Toxicology Approach to Screen the Hepatotoxic Ingredients in Traditional Chinese Medicines: Polygonum multiflorum Thunb as a Case Study

Biomolecules, 2019
In recent years, liver injury induced by Traditional Chinese Medicines (TCMs) has gained increasing attention worldwide. Assessing the hepatotoxicity of compounds in TCMs is essential and inevitable for both doctors and regulatory agencies.
Shuaibing He, Xuelian Zhang, Shan Lu, Ting Zhu, Guibo Sun, Xiaobo Sun   +5 more
doaj   +1 more source

COVID-19-Associated Liver Injury

Hepatic Medicine: Evidence and Research, 2023
Daniel T Gildea,1 Stephanie M Woo,2 Corinne E O’Connor,3 Amol S Rangnekar4 1Department of Internal Medicine, MedStar Georgetown University Hospital, Washington, DC, USA; 2Department of Gastroenterology, MedStar Georgetown University Hospital, Washington,
Gildea DT, Woo SM, O'Connor CE, Rangnekar AS   +3 more
doaj  

Exploratory Study of Autoantibody Profiling in Drug‐Induced Liver Injury with an Autoimmune Phenotype

Hepatology Communications, 2020
Drug‐induced liver injury (DILI) sometimes presents with an autoimmune hepatitis‐like phenotype (AI‐DILI), and it is challenging to distinguish it from de novo autoimmune hepatitis (AIH).
Craig Lammert, Chengsong Zhu, Yun Lian, Indu Raman, George Eckert, Quan‐Zhen Li, Naga Chalasani   +6 more
doaj   +1 more source

Lesión hepática inducida por medicamentos secundaria al consumo de esteroides androgénicos

Gaceta Médica Boliviana
El uso de esteroides anabólicos de forma ilícita es un problema en aumento que se caracteriza por el desconocimiento sobre los potenciales efectos secundarios a estos productos. El uso ilegal de los mismos ha llevado a un infra diagnóstico de los eventos
Juan sebastian Theran Leon, Laura Yibeth Esteban Badillo   +1 more
doaj   +1 more source

Bismuth subcitrate, metronidazole and tetracycline – a rare cause of drug-induced liver injury

European Journal of Case Reports in Internal Medicine, 2023
Drug-induced liver injury (DILI) is a liver condition caused by any drug or toxic substance. The spectrum of DILI manifestations can range from asymptomatic elevation of liver enzymes to acute liver failure.
Carina Silva, Susana Merim, Rita Sevivas, João Mota, Alexandra Leitão   +4 more
doaj   +1 more source

Turmeric-Induced Hepatotoxicity: Report of 2 Cases

International Medical Case Reports Journal, 2021
Aalam Sohal,1 Dhuha Alhankawi,2 Sunny Sandhu,1 JayaKrishna Chintanaboina2 1Department of Internal Medicine, UCSF Fresno, Fresno, CA, USA; 2Department of Gastroenterology and Hepatology, UCSF Fresno, Fresno, CA, USACorrespondence: Aalam Sohal 155 N Fresno
Sohal A, Alhankawi D, Sandhu S, Chintanaboina J   +3 more
doaj  

Antibiotic-Associated Drug-Induced Liver Injury in Critically Ill Children: A Prospective Observational Study

Безопасность и риск фармакотерапии
INTRODUCTION. Drug-induced liver injury (DILI) is associated, among other things, with the use of antibiotics. Children with DILI are at risk of acute liver failure and even death. However, the literature on the subject provides little information on the 
A. V. Vlasova, Yu. F. Shubina, D. A. Sychev   +2 more
doaj   +1 more source

The Incidence and Risk Factor Analysis of Drug Induced Liver Injury (Dili) in a Surabaya Hospital

Jurnal Farmasi Galenika (Galenika Journal of Pharmacy), 2018
The research has been conducted on the incident and analysis of risk factors drug liver injury (DILI) in a Surabaya Hospital. The aim of this study was to determine the incident of DILI, know which drugs cause DILI, and see the association of risk ...
Sherly Tandi Arrang, Widyati Widyati
doaj   +1 more source

Identification of average molecular weight (AMW) as a useful chemical descriptor to discriminate liver injury-inducing drugs.

PLoS ONE, 2021
Drug-induced liver injury (DILI) is one of major causes of discontinuing drug development and withdrawing drugs from the market. In this study, we investigated chemical properties associated with DILI using in silico methods, to identify a ...
Yuki Shimizu, Takamitsu Sasaki, Jun-Ichi Takeshita, Michiko Watanabe, Ryota Shizu, Takuomi Hosaka, Kouichi Yoshinari   +6 more
doaj   +1 more source

Urine metabolomics and microbiome analyses reveal the mechanism of anti-tuberculosis drug-induced liver injury, as assessed for causality using the updated RUCAM: A prospective study

Frontiers in Immunology, 2022
BackgroundAnti-tuberculosis drug-induced liver injury (ATB-DILI) is one of the most common adverse reactions that brings great difficulties to the treatment of tuberculosis. Thus, early identification of individuals at risk for ATB-DILI is urgent.
Ming-Gui Wang, Ming-Gui Wang, Shou-Quan Wu, Meng-Meng Zhang, Jian-Qing He   +4 more
doaj   +1 more source