Optimization of Hydroxy Propyl Methyl Cellulose and Carbomer In Diltiazem Hydrochloride Mucoadhesive Buccal Film [PDF]
Indonesian Journal of Pharmacy, 2021 Diltiazem hydrochloride (HCl) is a category of calcium channel blocker used as an antihypertensive agent. Diltiazem HCl is a low bioavailable drug due to high first-pass metabolism and a short half-life (3-5 hours); hence mucoadhesive buccal film was ...
Lina Winarti +2 more
doaj +4 more sources
Antimicrobial activities of Diltiazem Hydrochloride: drug repurposing approach [PDF]
PeerJBackground The growing concern of antibiotic-resistant microbial strains worldwide has prompted the need for alternative methods to combat microbial resistance.
Omar K. Alduaij +3 more
doaj +3 more sources
Antiviral Activity of Diltiazem HCl Against Pseudorabies Virus Infection In Vitro [PDF]
Veterinary SciencesPseudorabies virus (PRV) is a highly pathogenic agent that adversely impacts swine populations, leading to considerable economic losses within the Chinese pig industry.
Mengting Zuo +11 more
doaj +2 more sources
Transdermal delivery of Diltiazem HCl from matrix film: Effect of penetration enhancers and study of antihypertensive activity in rabbit model [PDF]
Journal of Advanced Research, 2016 Rabinarayan Parhi
exaly +2 more sources
Optimasi Hidroksipropil Metilselulosa dan Polivinil Pirolidon dalam Sediaan Mucoadhesive Buccal Film Diltiazem Hidroklorida [PDF]
, 2021 Diltiazem HCl is a class of benzodiazepine calcium channel blockers used to treat angina pectoris, arrhythmias, and hypertension. Diltiazem HCl improves first-pass metabolism, a short half time of 3-5 hours, and bioavailability of diltiazem for oral ...
Sari, Lusia Oktora Ruma Kumala +2 more
core +2 more sources
An Optimasi Polivinil Pirolidon dan Kitosan dalam Sediaan Mucoadhesive Buccal Film Diltiazem HCl [PDF]
, 2020 Diltiazem HCl adalah golongan benzoatiazepin penghambat kanal kalsium (calcium channel blocker) yang digunakan dalam pengobatan angina pektoris, aritmia, dan hipertensi. Diltiazem HCl mengalami first pass metabolism di hati, waktu paruh yang pendek yakni
Novita, Ulfia Dwi +2 more
core +2 more sources
Aptamer-based cocaine assay using a nanohybrid composed of ZnS/Ag2Se quantum dots, graphene oxide and gold nanoparticles as a fluorescent probe [PDF]
, 2020 Authors report on a new fluoro-graphene-plasmonic nanohybrid aptamer-based fluorescent nanoprobe for cocaine. To construct the nanoprobe, newly synthesized glutathione-capped ZnS/Ag 2Se quantum dots (QDs) were first conjugated to graphene oxide (GO) to ...
Abdolvand, Amin +4 more
core +2 more sources
Journal of Pharmaceutical Analysis, 2020 An understanding of the thermodynamics of the complexation process utilized in sustaining drug release in clay matrices is of great importance. Several characterisation techniques as well as isothermal calorimetry were utilized in investigating the ...
Ana-Maria Totea +7 more
doaj +1 more source
Optimasi Hydroxypropyl Methylcellulose dan Chitosan pada Tablet Floating-Mucoadhesive Diltiazem Hidroklorida Menggunakan Desain Faktorial [PDF]
, 2020 Diltiazem HCl is one of the drugs used for hypertension treatment. It requires frequent dosing, which is why diltiazem HCl needs to be formulated into preparations using a controlled release drug delivery system.
Sari, Lusia Oktora Ruma Kumala +2 more
core +2 more sources
A survey of Top 200 Drugs—Inconsistent Practice of Drug Strength Expression for Drugs Containing Salt Forms [PDF]
, 2012 Many ionizable drugs are developed and marketed as salt forms. However, there are no clear US regulatory guidelines on drug strength labeling for salts. The strengths of some drugs are expressed as salts and some as free acids/bases.
Prohotsky, Daniel, Zhao, Fang
core +2 more sources