Biodegradable microparticulate drug delivery system of diltiazem HCl [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2012 The efficacy of a drug in a specific application requires the maintenance of appropriate drug blood level concentration during a prolonged period of time.
Manish Kumar Gupta +2 more
doaj +4 more sources
Sodium Alginate - Gelatin Cross-Linked Microspheres for Releasing Diltiazem Hcl
Science Journal of University of Zakho, 2016 Semi-interpenetrating polymer network (semi-IPN) microspheres of Sodium alginate (NaAlg) and Gelatin were prepared and cross-linked with glutaraldehyde by using emulsification/solvent-evaporation method to deliver Diltiazem HCl as a model of drug ...
Alarqam Z. Tareq, Mohammed S. Hussein
doaj +2 more sources
DESIGN AND EVALUATION OF BILAYER FLOATING TABLETS OF DILTIAZEM HCL [PDF]
, 2017 The present investigation concerns design and evaluation of bilayer floating tablets of Diltiazem HCl Diltiazem HCl is Class I drug, though its reported bioavailability is only 40 %. It is having very short half life of 3 to 4 hrs.
Shaikh Siraj Nawaj*, Md. ZuberPatel,,G. J. Khan, Patel M Siddik,ZakirShaikh
core +2 more sources
Microencapsulation by spray coagulation of diltiazem HCl in calcium alginate-coated chitosan. [PDF]
AAPS PharmSciTech, 2008 The aim of this work was to develop a procedure for encapsulation of diltiazem HCl by spray coagulation. Factors affecting the formulations such as the effect of NaCl on the solubility of diltiazem in alginate solution, surface tension, pH, viscosity of the coagulation medium, and the effect of drug load on drug release were studied.
Tapia C, Montezuma V, Yazdani-Pedram M.
europepmc +7 more sources
The effect of pH and Polymer type on Release of Diltiazem HCl from hydrophilic matrices
Journal of Mazandaran University of Medical Sciences, 2007 Background and Purpose: Oral administrations have been used for many years as a main method comparing to other methods. Sustained release techniques have been a great interest recently.
J. Akbari, Ph.D. +3 more
doaj +1 more source
Anogenital Contact Dermatitis in Spain: A REIDAC Study of Patients Undergoing Patch Testing in 2019-2024. [PDF]
Contact DermatitisAllergic contact dermatitis is very common in patients with anogenital lesions referred for patch testing in Spain. Key allergens include fragrances, preservatives and topical treatments like anaesthetics and steroids. Emerging sensitisers including benzisothiazolinone and sodium metabisulphite are also relevant.
Grau-Pérez M +29 more
europepmc +2 more sources
Neuron-non-neuron electrical coupling networks are involved in chronic stress-induced electrophysiological changes in lateral habenular neurons. [PDF]
J PhysiolAbstract figure legend We investigated electrophysiological changes in lateral habenula (LHb) neurons induced by chronic social defeat stress in mice. LHb neurons exhibited short (<400 ms) rebound depolarizing potentials (short‐RDPs) or long‐RDPs (order of seconds) (long‐RDPs) after the offset of hyperpolarization. The incidence of long‐RDP neurons was
Yamaoka K +12 more
europepmc +2 more sources
Influence of Organic Acids on Diltiazem HCl Release Kinetics from Hydroxypropyl Methyl Cellulose Matrix Tablets. [PDF]
J Young Pharm, 2010 The matrix tablets of diltiazem hydrochloride were prepared by direct compression using hydroxypropyl methyl cellulose (HPMC) and various amounts (2.5%, 5.0%, 10% and 20%) of citric acid, malic acid and succinic acid. The characterization of physical mixture of drug and organic acids was performed by Infra-red spectroscopy.
Sateesha S, Rajamma A, Narode M, Vyas B.
europepmc +4 more sources
An investigation into the stabilization of diltiazem HCl release from matrices made from aged polyox powders. [PDF]
AAPS PharmSciTech, 2013 Matrices containing PEO fail to provide stable drug release profiles when stored at elevated temperatures for a period of time. The present study aims to stabilize diltiazem HCl release from matrices made from various molecular weights of polyox powders.
Shojaee S +4 more
europepmc +4 more sources
Development and release mechanism of diltiazem HCl prolonged release matrix tablets [PDF]
Drug Delivery, 2009 A coated matrix tablet formulation has been used to develop controlled release diltiazem HCl (DIL) tablets. The developed drug delivery system provided prolonged drug release rates over a defined period of time. DIL tablets prepared using dry mixing and direct compression and the core consisted of hydrophilic and hydrophobic polymers such as ...
Harikrishna, Boyapally +2 more
openaire +2 more sources