Results 21 to 30 of about 4,501 (180)

Design & Evaluation of Pulsatile Drug Delivery of Diltiazem Hcl

International Journal For Multidisciplinary Research, 2023
Oral controlled drug delivery systems represent the most popular form of controlled drug delivery systems for the obvious advantages of oral route of drug administration.
BHUKYA NAGARAJU -, M ANVESH RAJ -, Nagaraju B. -   +2 more
openaire   +1 more source

Standard Protocols for Characterising Primary and In Vitro-Generated Human Hepatocytes. [PDF]

J Cell Mol Med
ABSTRACT Hepatocyte‐like cells (HLCs) derived from pluripotent stem cells (PSCs) or direct reprogramming are an unlimited source of human hepatocytes for biomedical applications. HLCs are used to model human diseases, develop precise drugs and establish groundbreaking regenerative cell‐based therapies.
Heydari Z, Gramignoli R, Piryaei A, Zahmatkesh E, Pooyan P, Seydi H, Nussler A, Szkolnicka D, Rashidi H, Najimi M, Hay DC, Vosough M.   +11 more
europepmc   +2 more sources

Formulation and In-Vitro Evaluation of Mucoadhesive Diltiazem Hydrochloride Buccal Tablets

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2011
Mucoadhesive tablets for buccal administration of diltiazem hydrochloride were prepared as an alternative to available diltiazem HCl dosage forms. Two types of tablets were developed each containing two mucoadhesive components (hydroxypropylmethyl ...
Lubna A. Sabri
doaj   +1 more source

Clinical Experience with Diltiazem in the Treatment of Cardiovascular Diseases [PDF]

, 2016
Cardiovascular diseases are the leading cause of death in the world. Coronary artery diseases, atrial fibrillation or hypertensive heart disease, are among the most important cardiovascular disorders. Hypertension represents a significant risk factor for
Alejandro de la Sierra, Antonio Hernández Madrid, Domingo Marzal Martín, Gonzalo Barón-Esquivias, Luis Rodríguez Padial, Vicente Pallarés-Carratalá   +5 more
core   +4 more sources

Formulation and evaluation of floating mucoadhesive alginate beads for targetingHelicobacter pylori [PDF]

, 2015
Objectives: There are various obstacles in the eradication of Helicobacter.pylori (H. pylori) infections, including low antibiotic levels and poor accessibility of the drug at the site of the infection.
Adebisi, Adebisi, Adeola O. Adebisi, Ahuja, Akiyama, Bai, Bajpai, Barbara R. Conway, Batchelor, Bazzoli, Boddupalli, Cammarota, Castro, Chun, Desai, Dunn, Dupuy, Erah, Erah, Ernst, Gal, Georgopoulos, Gåserød, Higuchi, Hixson, Iijima, Ikeda, Ishak, Kawahara, Khanvilkar, Kohri, Korsmeyer, Lee, Lehmann, Malfertheiner, Miyazaki, Moore, Murata, Murray, Najib, Nakagawa, Nayak, Norris, Park, Pasparakis, Pereira, Peter R. Laity, Peterson, Rajinikanth, Romero, Rothenbacher, Singh, Smrdel, Stops, Suerbaum, Suzuki, Umamaheshwari, Varum, Whitehead, Østberg   +59 more
core   +1 more source

Exploring calcium channel blocker as a candidate drug for Pseudomonas aeruginosa through network pharmacology and experimental validation

Chemical Biology &Drug Design, Volume 102, Issue 6, Page 1353-1366, December 2023., 2023
Calcium channel blocker (CCB) is known to possess antibacterial effects. We aimed to apply network pharmacology (docking and protein–protein interaction [PPI] analyses) to predict the potential targets and mechanisms of CCB against Pseudomonas aeruginosa as well as to verify the effect of these drugs.
Zijun Yan, Liangjing Xia, Xingmeng Xu, Bingsuo Ma, Xiaoyan Yuan, Kun Yang, Kexin Li, Xianwen Ye, Liangming Zhang, Tong Chen   +9 more
wiley   +1 more source

Development and evaluation of diltiazem hydrochloride controlled-release pellets by fluid bed coating process

Journal of Advanced Pharmaceutical Technology & Research, 2013
The aim of the present study was to develop controlled-release pellets of diltiazem HCl with ethyl cellulose and hydroxylpropyl methylcellulose phthalate as the release rate retarding polymers by fluid bed coating technique.
Mikkilineni Bhanu Prasad, Suryadevara Vidyadhara, Reddyvalam Lankapalli C Sasidhar, Talamanchi Balakrishna, Pavuluri Trilochani   +4 more
doaj   +1 more source

DILTIAZEM HCL: EVALUATION OF ITS PRESENCE IN BANGLADESH

International Research Journal of Pharmacy, 2014
Diltiazem hydrochloride is a calcium channel blocker used for the treatment of chronic stable angina pectoris as well as for angina pectoris caused by a coronary arterial spasm and systemic hypertension. In spite of these life - saving health benefits, this drug molecule has been found to be losing its market value in Bangladesh du e its side effects ...
Rahman Kabir Eva, Samin Huq
openaire   +1 more source

Kompleks Polielektrolit Kitosan-Xanthan sebagai Matriks Sediaan Mukoadhesif

Pharmaceutical Sciences and Research, 2017
Mucoadhesive dosage form is a pharmaceutical dosage form with prolonged gastric residence time which can increase bioavailability of drugs. An excipient with suitable swelling and bioadhesive characteristics plays important role to obtain good ...
Kurnia Sari Setio Putri, Silvia Surini, Bambang Sulistomo   +2 more
doaj   +1 more source

Formulation and Evaluation of Chitosan-Gellan Beads as Controlled Drug Delivery System of Antihypertensive Drug

Journal of Basic and Applied Research in Biomedicine, 2022
The use of natural polymers in the design of drug delivery formulation has received much attention due to their excellent biocompatibility and biodegradability.
Rohit Bhosale, Riyaz Ali Osmani, H Gangadharappa   +2 more
doaj   +2 more sources