Results 21 to 30 of about 4,456 (181)
A survey of Top 200 Drugs—Inconsistent Practice of Drug Strength Expression for Drugs Containing Salt Forms [PDF]
Many ionizable drugs are developed and marketed as salt forms. However, there are no clear US regulatory guidelines on drug strength labeling for salts. The strengths of some drugs are expressed as salts and some as free acids/bases.
Prohotsky, Daniel, Zhao, Fang
core +2 more sources
Clinical Experience with Diltiazem in the Treatment of Cardiovascular Diseases [PDF]
Cardiovascular diseases are the leading cause of death in the world. Coronary artery diseases, atrial fibrillation or hypertensive heart disease, are among the most important cardiovascular disorders. Hypertension represents a significant risk factor for
Alejandro de la Sierra +5 more
core +4 more sources
Optimasi Hydroxypropyl Methylcellulose dan Chitosan pada Tablet Floating-Mucoadhesive Diltiazem Hidroklorida Menggunakan Desain Faktorial [PDF]
Diltiazem HCl is one of the drugs used for hypertension treatment. It requires frequent dosing, which is why diltiazem HCl needs to be formulated into preparations using a controlled release drug delivery system.
Sari, Lusia Oktora Ruma Kumala +2 more
core +2 more sources
Formulation and In-Vitro Evaluation of Mucoadhesive Diltiazem Hydrochloride Buccal Tablets
Mucoadhesive tablets for buccal administration of diltiazem hydrochloride were prepared as an alternative to available diltiazem HCl dosage forms. Two types of tablets were developed each containing two mucoadhesive components (hydroxypropylmethyl ...
Lubna A. Sabri
doaj +1 more source
Formulation and evaluation of floating mucoadhesive alginate beads for targetingHelicobacter pylori [PDF]
Objectives: There are various obstacles in the eradication of Helicobacter.pylori (H. pylori) infections, including low antibiotic levels and poor accessibility of the drug at the site of the infection.
Adebisi +59 more
core +1 more source
Calcium channel blocker (CCB) is known to possess antibacterial effects. We aimed to apply network pharmacology (docking and protein–protein interaction [PPI] analyses) to predict the potential targets and mechanisms of CCB against Pseudomonas aeruginosa as well as to verify the effect of these drugs.
Zijun Yan +9 more
wiley +1 more source
The aim of the present study was to develop controlled-release pellets of diltiazem HCl with ethyl cellulose and hydroxylpropyl methylcellulose phthalate as the release rate retarding polymers by fluid bed coating technique.
Mikkilineni Bhanu Prasad +4 more
doaj +1 more source
DILTIAZEM HCL: EVALUATION OF ITS PRESENCE IN BANGLADESH
Diltiazem hydrochloride is a calcium channel blocker used for the treatment of chronic stable angina pectoris as well as for angina pectoris caused by a coronary arterial spasm and systemic hypertension. In spite of these life - saving health benefits, this drug molecule has been found to be losing its market value in Bangladesh du e its side effects ...
Rahman Kabir Eva, Samin Huq
openaire +1 more source
Kompleks Polielektrolit Kitosan-Xanthan sebagai Matriks Sediaan Mukoadhesif
Mucoadhesive dosage form is a pharmaceutical dosage form with prolonged gastric residence time which can increase bioavailability of drugs. An excipient with suitable swelling and bioadhesive characteristics plays important role to obtain good ...
Kurnia Sari Setio Putri +2 more
doaj +1 more source
The use of natural polymers in the design of drug delivery formulation has received much attention due to their excellent biocompatibility and biodegradability.
Rohit Bhosale +2 more
doaj +2 more sources

