Results 51 to 60 of about 4,501 (180)

An In-Depth Examination of Formularies and Other Features of Medicare Drug Plans [PDF]

open access: yes, 2006
Provides a detailed assessment of the formularies, drug costs, and utilization management tools offered by the fourteen nationwide organizations that account for most of the stand-alone prescription drug ...
Elizabeth Hargrave   +3 more
core  

In vitro evaluation of a morphine polymeric complex: flowability behavior and dissolution study [PDF]

open access: yes, 2004
The purpose of this research was to perform a granulometrical and flow properties study of a morphine polymeric complex and determine the influence of 3 variables—particle size of complex, pH value, and ionic strength of the dissolution medium—on the
Fernández Arévalo, María Mercedes   +3 more
core   +1 more source

Calcium Channel Blocker Lacidipine Promotes Antitumor Immunity by Reprogramming Tryptophan Metabolism

open access: yesAdvanced Science, Volume 12, Issue 3, January 20, 2025.
The antihypertensive drug lacidipine, as a bifunctional modulator of the enzymatic activity and expression of indoleamine 2,3‐dioxygenase 1 (IDO1), targets calcium channels to inhibit (Protein Tyrosine 2 (Pyk2)‐Janus Kinase 1 (JAK1)‐calmodulin complex‐mediated IDO1 immunosuppression.
Yuwen Sheng   +9 more
wiley   +1 more source

Controlled release floating multiparticulates of metoprolol succinate by hot melt extrusion [PDF]

open access: yes, 2015
YesWe present hot melt extrusion (HME) for the design of floating multiparticulates. Metoprolol succinate was selected as the model drug. Our foremost objective was to optimize the components Eudragit® RS PO, polyethylene oxide (PEO) and hydroxypropyl ...
Devarajan, P.V.   +2 more
core   +1 more source

In vitro Assessment of the Adsorption Efficacy of Activated Charcoal versus Kaolin on some used Medications of Narrow Index of Safety

open access: yesIraqi Journal of Pharmaceutical Sciences
The purpose of this study is to investigate the in vitro adsorption power of activated charcoal (AC), light kaolin (LK), and heavy kaolin (HK) at a concentration of 0.2% weight-per-volume (w/v) on high dosages (10 tablets) of a variety of medications ...
Asmaa Abdelaziz Mohamed   +3 more
doaj   +1 more source

Impact of a Green Cabbage‐Based Diet on Selected Proinflammatory Cytokines and Hormones in Pre‐Eclamptic Rats

open access: yesJournal of Food Biochemistry, Volume 2025, Issue 1, 2025.
The growing interest in functional foods has led to the utilization of various vegetables for their nutritional benefits. This study focused on the development and evaluation of a green cabbage‐enriched meal and the investigation of the impact of the enriched cookies on selected proinflammatory cytokines and hormones in pre‐eclamptic Wistar rats.
Omolola Mary Omosebi   +3 more
wiley   +1 more source

Optimasi Tepung Lidah Buaya (Aloe Vera L.) Dan Carbopol 934p Sebagai Mucoadhesive Agent Pada Sediaan Mikrogranul Ranitidin Hcl Secara Simplex Lattice Design [PDF]

open access: yes, 2017
Ranitidin Hidroklorida merupakan antagonis reseptor histamin H2 secara selektif dan reversible dengan waktu paruh yang pendek yaitu 2,5-3 jam, sehingga perlu dikembangkan sediaan lepas lambat dalam bentuk mucoadhesive.
Cahyani, R. H. (Revita)
core  

A novel approach to crystallisation of nanodispersible microparticles by spray drying for improved tabletability [PDF]

open access: yes, 2012
YesHigh-dose API powders which are to be tableted by direct compression should have high compactibility and compressibility. This note reports on a novel approach to the manufacture of crystalline powders intended for direct compaction with improved ...
Adamczyk, B.   +4 more
core   +1 more source

Tools for clinical pharmacists to identify medications that can cause drug‐induced cognitive impairment: A systematic review

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 7, Issue 12, Page 1207-1227, December 2024.
Abstract Cognitive impairment affects around 19% of community‐dwelling older adults in the United States. Pharmacists can play a significant role in identifying and deprescribing cognitive‐impairing medications through cognitive‐focused medication reviews or as part of comprehensive medication management.
Jacob Stanton   +4 more
wiley   +1 more source

On the dilemma of fractal or fractional kinetics in drug release studies: A comparison between Weibull and Mittag-Leffler functions

open access: yes, 2018
We compare two of the most successful models for the description and analysis of drug release data. The fractal kinetics approach leading to release profiles described by a Weibull function and the fractional kinetics approach leading to release profiles
Kosmidis, Kosmas, Macheras, Panos
core   +1 more source

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