Results 31 to 40 of about 2,282 (176)
Lipids in Health and Disease, 2011 Background and aims The present study was aimed to analyze the chemical composition of ground apricot kernel (GAK) and examine its effect on hepatic fibrosis in vivo induced by dimethylnitrosamine (DMN) in rats.
Abdel-Rahman Manal K
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Alexandria Journal of Medicine, 2014 Hepatocellular carcinomas will emerge as a major form of malignancy in the coming decades. When these tumors are in advanced stages, few therapeutic options are available.
Neveen Abd El Moneim Hussein +6 more
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Precursors of Dimethylnitrosamine in Fried Bacon
Journal of Food Protection, 1978 Various compounds, all of which are endogenous to bacon systems, were investigated as precursors of dimethylnitrosamine. Low moisture model system studies indicated that dimethylamine and sarcosine were the major contributors to dimethylnitrosamine formation. Under conditions normally encountered in pan-frying of bacon, choline-containing compounds and
J I, Gray, M E, Collins, B, MacDONALD
openaire +2 more sources
SIRT Family: Biological Functions and Therapeutic Targets
MedComm, Volume 7, Issue 8, August 2026.SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang +9 more
wiley +1 more source
Journal of Lipid Research, 2009 Sphingosine 1-phosphate (S1P), a bioactive lipid mediator, stimulates proliferation and contractility in hepatic stellate cells, the principal matrix-producing cells in the liver, and inhibits proliferation via S1P receptor 2 (S1P2) in hepatocytes in ...
Hitoshi Ikeda +14 more
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Antioxidants, 2021 Oligonol is a low molecular weight polyphenol product derived from lychee fruit by a manufacturing process. We investigated oligonol’s anti-fibrotic effect and the underlying mechanism in dimethylnitrosamine (DMN)-induced chronic liver damage in male ...
Changyong Lee +3 more
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Food Frontiers, Volume 7, Issue 4, July 2026.A rapid and sensitive method for simultaneous adsorption and determination of AFB1 and ZEN in corn and wheat was developed by CAB‐MMOF‐based MSPE coupled with HPLC‐FD. ABSTRACT In this study, a novel core‐shell structured cocoamidopropyl betaine‐functionalized magnetic metal‐organic framework (CAB‐MMOF) was designed and synthesized through post ...
Fuchao Zhang +7 more
wiley +1 more source
Cell Transplantation, 2002 We studied the effect of preoperative hepatocyte transplantation on the prevention of liver failure in cirrhotic rats after hepatic resection. Two groups of Lewis rats were rendered cirrhotic by IP injection of 1% dimethylnitrosamine and were subjected ...
Tarik A. Ahmad M.D. +7 more
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Pesquisa Veterinária Brasileira, 2009 The connexin 32 (Cx32) is a protein that forms the channels that promote the gap junction intercellular communication (GJIC) in the liver, allowing the diffusion of small molecules through cytosol from cell-to-cell. Hepatic fibrosis is characterized by a
Alexandro dos S. Rodrigues +5 more
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Pharmaceutical Biology, 2020 Context Fuzheng Huayu recipe (FZHY) combined with entecavir (ETV) is used to treat the cirrhosis caused by chronic hepatitis B (CHB) infection. Objective To investigate the effect of FZHY on ETV pharmacokinetics under different conditions.
Tao Yang +7 more
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