Results 121 to 130 of about 2,551 (177)
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Dimethyltryptamine Experiments with Psychotics
Journal of Mental Science, 1958The so-called experimental psychoses have been in the focus of increased interest recently, as a result of the discovery of new hallucinogenic or psychotic agents and of the fact that the problems can be approached more closely even in the borderline fields of pathopsychological research (biochemistry, electrophysiology, etc.) owing to advance in ...
Z, BOSZORMENYI, S, SZARA
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Comparison of a placebo, N-dimethyltryptamine, and 6-hydroxy-N-dimethyltryptamine in man
Psychopharmacologia, 19631. Five human subjects received intramuscularly at weekly intervals a placebo and equal doses of 6-hydroxy-N-dimethyltryptamine (6-HDMT) and N-dimethyltryptamine (DMT) (1 mg/kg, 4 subjects; 0.75 mg/kg, 1 subject). 2. DMT produced markedly significant mental effects including anxiety, hallucinations, and perceptual distortions and ...
D E, ROSENBERG, H, ISBELL, E J, MINER
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Dimethyltryptamine: Endogenous Role and Therapeutic Potential [PDF]
Journal of Psychoactive Drugs, 2019 N, N-dimethyltryptamine (DMT) is an indole alkaloid produced by a number of plants and animals, including humans. Its psychoactive effects were first described in 1956 by Stephen Szára, but have been exploited for centuries by South American indigenous populations in the form of ayahuasca. In the present review, we assess the state of the art regarding
Alexandra Vsl, Rodrigues +2 more
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In vivo metabolism of 5-methoxy-N, N-dimethyltryptamine and N,N-dimethyltryptamine in the rat
Biochemical Pharmacology, 1987Following intraperitoneal administration, 5-methoxy-N,N-dimethyltryptamine and N,N-dimethyltryptamine are subject to both a very rapid uptake into, and clearance from, all tissues examined. The current studies in vivo confirm previous in vitro observations that the routes involved in the metabolism of these compounds include oxidative deamination, N ...
B R, Sitaram +4 more
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Metabolic Engineering, 2023
N,N-dimethyltryptamine (DMT), 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) and 5-hydroxy-N,N-dimethyltryptamine (bufotenine) are psychedelic tryptamines found naturally in both plants and animals and have shown clinical potential to help treat mental disorders, such as anxiety and depression.
Lucas M. Friedberg +6 more
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N,N-dimethyltryptamine (DMT), 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) and 5-hydroxy-N,N-dimethyltryptamine (bufotenine) are psychedelic tryptamines found naturally in both plants and animals and have shown clinical potential to help treat mental disorders, such as anxiety and depression.
Lucas M. Friedberg +6 more
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Phytochemistry, 1972
Abstract The biosynthesis and turnover of N , N -dimethyltryptamine and 5-methoxy- N , N -dimethyltryptamine have been studied in the pasture grass Phalaris tuberosa by a combination of feeding and trapping experiments using radioisotopically labelled compounds. Their turnover has been demonstrated by feeding tryptophan and tryptamine.
M Slaytor
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Abstract The biosynthesis and turnover of N , N -dimethyltryptamine and 5-methoxy- N , N -dimethyltryptamine have been studied in the pasture grass Phalaris tuberosa by a combination of feeding and trapping experiments using radioisotopically labelled compounds. Their turnover has been demonstrated by feeding tryptophan and tryptamine.
M Slaytor
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A Dimethyltryptamine-Forming Enzyme in Human Blood
American Journal of Psychiatry, 1973An enzyme capable of forming the hallucinogen dimethyltryptamine was found in human red blood cells, plasma, and platelets. The enzyme activity in red blood cells and plasma was not significantly different in psychiatric patients from that in normal subjects.
R J, Wyatt, J M, Saavedra, J, Axelrod
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Urinary Excretion of Dimethyltryptamine in Liver Disease
American Journal of Psychiatry, 1979The urinary excretion of N,N-dimethyltryptamine (DMT) was higher in patients with severe liver disease than in normal subjects. This difference remained significant when patients with all grades of hepatic encephalopathy were excluded. Patients with liver disease whose mental states were normal excreted amounts of DMT similar to those of patients with ...
S A, Checkley +5 more
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Urinary dimethyltryptamine and psychiatric symptomatology and classification
Psychological Medicine, 1977SynopsisThe excretion of dimethyltryptamine (DMT) was studied amongst 122 recently admitted psychiatric patients and 20 normal subjects. DMT was detected in the urine of 47% of those diagnosed by their psychiatrists as schizophrenic, 38% of those with other non-affective psychoses, 13% of those with affective psychoses, 19% of those with neurotic and ...
R, Rodnight +5 more
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N,N-Dimethyltryptamine–Induced Psychosis
Clinical Neuropharmacology, 2015N,N-dimethyltryptamine (DMT) is a 5-hydroxytryptamine 2A and 1A receptor agonist that exhibits potent psychoactive properties in humans. Recreational use of this drug has increased precipitously and is likely to result in an increase in patients presenting with substance-induced psychoses. The present case provides an early example of substance-induced
Neil E, Paterson +2 more
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