Results 11 to 20 of about 9,241 (226)

Diosgenin hemihydrate [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2012
Diosgenin [or (22R,25R)-spirost-5-en-3β-ol] is the starting material of the Marker degradation, a cheap semi-synthesis of progesterone, which has been designated as an International Historic Chemical Landmark. Thus far, a single X-ray structure for diosgenin is known, namely its dimethyl sulfoxide solvate [Zhanget al.(2005).Acta Cryst.E61, o2324–o2325].
María-Guadalupe Hernández Linares   +4 more
openaire   +3 more sources

Fabrication and Assessment of Diosgenin Encapsulated Stearic Acid Solid Lipid Nanoparticles for Its Anticancer and Antidepressant Effects Using in vitro and in vivo Models

open access: yesFrontiers in Neuroscience, 2022
Inflammatory cascade plays a pivotal role in the onset and progression of major depressive disorder (MDD) and glioblastoma multiforme (GBM). Therefore, questing natural compounds with anti-inflammatory activity such as diosgenin can act as a double-edged
Hina Khan   +5 more
doaj   +1 more source

Altering Sterol Composition Implied That Cholesterol Is Not Physiologically Associated With Diosgenin Biosynthesis in Trigonella foenum-graecum

open access: yesFrontiers in Plant Science, 2021
Diosgenin serves as an important precursor of most steroidal drugs in market. Cholesterol was previously deemed as a sterol origin leading to diosgenin biosynthesis.
Liyang Cao   +7 more
doaj   +1 more source

Anti-Allergic Diarrhea Effect of Diosgenin Occurs via Improving Gut Dysbiosis in a Murine Model of Food Allergy

open access: yesMolecules, 2021
Although the anti-allergic and prebiotic activities of diosgenin have been reported, the influence of diosgenin on intestinal immune and epithelial cells remains unclear.
Chung-Hsiung Huang   +5 more
doaj   +1 more source

Fenugreek (Trigonella Foenum-Graecum) Seed Flour and Diosgenin Preserve Endothelium-Dependent Arterial Relaxation in a Rat Model of Early-Stage Metabolic Syndrome [PDF]

open access: yes, 2018
K
Gesztelyi, Rudolf   +9 more
core   +5 more sources

The role of diallyl thiosulfinate associated with nuciferine and diosgenin in the treatment of premature ejaculation: a pilot study [PDF]

open access: yes, 2018
Objective: To assess the efficacy and safety of an association of diallyl thiosulfinate with nuciferine and diosgenin in the treatment of a group of patients suffering from premature ejaculation (PE), primary or secondary to erectile dysfunction (ED ...
Cai, Tommaso   +10 more
core   +2 more sources

Diosgenin stimulation of fecal cholesterol excretion in mice is not NPC1L1 dependent

open access: yesJournal of Lipid Research, 2009
Diosgenin exists in some food supplements and herbal medicines and lowers plasma cholesterol by increasing fecal cholesterol excretion. It is believed that diosgenin promotes fecal cholesterol excretion by stimulating biliary cholesterol secretion and ...
Ryan E. Temel   +7 more
doaj   +1 more source

Crossing Lilium Orientals of different ploidy creates Fusarium-resistant hybrid [PDF]

open access: yes, 2010
Oriental hybrid lily is of great commercial value, but it is susceptible to Fusarium disease that causes a significant loss to the production. A diploid Oriental hybrid resistant to Fusarium, Cai-74, was diploidized from triploid obtained from the ...
Liu Feihu   +3 more
core   +2 more sources

Neuroprotective effect of diosgenin in a mouse model of diabetic peripheral neuropathy involves the Nrf2/HO-1 pathway

open access: yesBMC Complementary Medicine and Therapies, 2020
Background Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes. Diosgenin is a natural steroidal saponin with a variety of beneficial effects, including antidiabetic effects, and is a raw material for the ...
Jinhong Leng   +9 more
doaj   +1 more source

Diosgenin, an Activator of 1,25D3-MARRS Receptor/ERp57, Attenuates the Effects of TNF-α by Causing ADAM10-Dependent Ectodomain Shedding of TNF Receptor 1

open access: yesCellular Physiology and Biochemistry, 2017
Background/Aims: We investigated how diosgenin, a steroidal sapogenin, has anti-tumor necrosis factor-α (TNF-α) effects in human aortic endothelial cells (HAECs).
Won Seok Yang   +4 more
doaj   +1 more source

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