Results 11 to 20 of about 501 (137)
Acta Crystallographica Section E Structure Reports Online, 2012 Diosgenin [or (22R,25R)-spirost-5-en-3β-ol] is the starting material of the Marker degradation, a cheap semi-synthesis of progesterone, which has been designated as an International Historic Chemical Landmark. Thus far, a single X-ray structure for diosgenin is known, namely its dimethyl sulfoxide solvate [Zhanget al.(2005).Acta Cryst.E61, o2324–o2325].
María-Guadalupe Hernández Linares +4 more
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The Equilibria of Diosgenin–Phosphatidylcholine and Diosgenin–Cholesterol in Monolayers at the Air/Water Interface [PDF]
The Journal of Membrane Biology, 2016 Diosgenin (Dio) has shown many treatment properties, but the most important property is cytotoxic activity in cancer cells. In this study, we investigated monolayers of Dio, cholesterol (Ch), and phosphatidylcholine (PC) at the air/water interface. The measurements were carried with a Langmuir Teflon trough and a Nima 9000 tensiometer program.
Janicka, Katarzyna +2 more
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BMC Complementary Medicine and Therapies, 2020 Background Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes. Diosgenin is a natural steroidal saponin with a variety of beneficial effects, including antidiabetic effects, and is a raw material for the ...
Jinhong Leng +9 more
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Open Life Sciences, 2021 Gastric mucosal injury is caused by an imbalance between the mucosal defense and gastro-irritants, leading to gastroenteritis. Diosgenin is a steroidal sapogenin found in the wild Yam plant that has been reported with several pharmacological properties ...
Zhao Hengfang +3 more
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Characterization of spray dried diosgenin from fenugreek using binary blend of carrier agents
Applied Food Research, 2022 The utilization of nutraceutical products is enhancing widely due to upcoming diseases. Consumption of bitter food is remarkably less irrespective of their health benefits.
Prajya Arya, Pradyuman Kumar
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The role of diosgenin in crohn’s disease [PDF]
Clinical Phytoscience, 2022 AbstractInflammatory bowel disease (IBD) is a chronic idiopathic inflammation that can grossly affect the entire gastrointestinal tract (GIT) from the mouth to the anus. Crohn’s disease is the most known type of IBD and has been the focus of attention due to its increase in prevalence worldwide.
Sunday Ogundepo +9 more
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Immunity, Inflammation and Disease, 2022 Introduction Diosgenin is a natural steroidal compound with reported antidiabetic and many other protective properties. This study aimed to explore the protective effect of diosgenin on high‐glucose (HG)‐induced retinal pigment epithelial cells.
Yang Hao, Xuefeng Gao
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Hydroxylation of Diosgenin by Absidia coerulea [PDF]
Natural Product Communications, 2010 Microbial transformation of diosgenin (1) using Absidia coerulea yielded five new polar metabolites, which were identified as (25 R)-spirost-5-en-3β,7β,12β,25α-tetrol (2), (25 S)-spirost-5-en-3β,7α,12β,25β-tetrol (3), (25 S)-spirost-5-en-3β,7β,12β,25β-tetrol (4), (25 R)-spirost-5-en-3β,7α,12β,25α-tetrol (5), and (25 R)-spirost-5-en-3β,7β,12β,24β-tetrol
Ying, Zhao +5 more
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Pharmacokinetic Analysis of Diosgenin in Rat Plasma by a UPLC-MS/MS Approach
Journal of Analytical Methods in Chemistry, 2022 Diosgenin, a steroidal sapogenin, has attracted attention worldwide owing to its pharmacological properties, including antitumor, cardiovascular protective, hypolipidemic, and anti-inflammatory effects.
Pei Liu +10 more
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Effect of diosgenin on lipid metabolism in rats.
Journal of Lipid Research, 1979 The purpose of this study was to determine whether diosgenin suppresses cholesterol absorption in rats, and to examine relevant changes in cholesterol and bile acid metabolism.
M N Cayen, D Dvornik
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