Results 11 to 20 of about 5,720 (220)
Acta Crystallographica Section E Structure Reports Online, 2012 Diosgenin [or (22R,25R)-spirost-5-en-3β-ol] is the starting material of the Marker degradation, a cheap semi-synthesis of progesterone, which has been designated as an International Historic Chemical Landmark. Thus far, a single X-ray structure for diosgenin is known, namely its dimethyl sulfoxide solvate [Zhanget al.(2005).Acta Cryst.E61, o2324–o2325].
María-Guadalupe Hernández Linares +4 more
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HPTLC determination of diosgenin in fenugreek seeds
Acta Pharmaceutica, 2018 Abstract A new HPTLC-densitometric method for diosgenin determination in fenugreek seeds was established after optimization of the conditions for efficient saponin extraction and acid hydrolysis. Several procedures were tested, the best of which was a three-step Soxhlet extraction, followed by hydrolysis of the ...
Król-Kogus Barbara +4 more
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Diosgenin, a Novel Aldose Reductase Inhibitor, Attenuates the Galactosemic Cataract in Rats [PDF]
Journal of Diabetes Research, 2017 Objective. To seek efficient aldose reductase inhibitors (ARIs) with excellent in vitro and in vivo biological activities against rat galactosemic cataract. Methods.
Lixia Ji, Lixia Cheng, Zhihong Yang
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Diosgenin from Solanum Species
, 1969 Diosgenin from Solanum ...
Sipra Mookherjea, Rabecca Mathew
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Pharmacokinetic Analysis of Diosgenin in Rat Plasma by a UPLC-MS/MS Approach
Journal of Analytical Methods in Chemistry, 2022 Diosgenin, a steroidal sapogenin, has attracted attention worldwide owing to its pharmacological properties, including antitumor, cardiovascular protective, hypolipidemic, and anti-inflammatory effects.
Pei Liu +10 more
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Effect of Chitosan-Diosgenin Combination on Wound Healing
International Journal of Molecular Sciences, 2023 The difficult-to-heal wounds continue to be a problem for modern medicine. Chitosan and diosgenin possess anti-inflammatory and antioxidant effects making them relevant substances for wound treatment. That is why this work aimed to study the effect of the combined application of chitosan and diosgenin on a mouse skin wound model.
Lubomir Petrov +9 more
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Molecularly imprinted polymers for diosgenin [PDF]
, 2019 Diosgenin is steroid sapogenin used in therapies of many diseases such as breast cancer, cervix cancer, prostate cancer, certain forms of leukemia and in infertility therapy. Diosgenin is a precursor for production of other significant steroidal compounds such as dehydroepiandrosterone [1].
Ugrinov, Stefan +3 more
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Rewiring Steroidal Metabolic Pathways for Diosgenin Production in Solanum nigrum. [PDF]
Plant Biotechnol JABSTRACT Diosgenin is a key starting material for the synthesis of steroidal drugs, such as corticosteroids and sex hormones. While the primary commercial source of diosgenin is the tubers of Dioscorea spp., identifying alternative plant hosts capable of diosgenin biosynthesis could enhance its production.
Lim J +16 more
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<i>Polygonati Rhizoma</i> Attenuates Oxidative Stress-Induced Senescence in Periodontal Ligament Stem Cells. [PDF]
Food Sci NutrNetwork pharmacology identified the potential targets and pathways of Polygonati Rhizoma (PR) against aging‐related periodontitis through PPI, GO/KEGG enrichment, and molecular docking. Experimental validation in a D‐galactose‐induced senescence model of periodontal ligament stem cells showed that PR‐medicated serum attenuated cellular senescence and ...
Feng X +6 more
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Ligand-Independent Activation of Notch1 by Cathepsin L Induces CUX1/p16<sup>INK4a</sup>-Dependent Endothelial Senescence Associated With Atherosclerosis. [PDF]
Aging CellCTSL activates Notch1/RBPJ in a ligand‐independent fashion, inducing CUX1/p16INK4a‐dependent endothelial senescence associated with atherosclerosis. ABSTRACT Our post‐GWAS functional analysis revealed that cathepsin L (CTSL) is an upstream regulator of CUX1, and it induces p16INK4a‐dependent and atherosclerosis‐associated senescence by indirectly ...
Wu Y +13 more
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