Results 21 to 30 of about 9,241 (226)

Gastroprotective effects of diosgenin against HCl/ethanol-induced gastric mucosal injury through suppression of NF-κβ and myeloperoxidase activities

open access: yesOpen Life Sciences, 2021
Gastric mucosal injury is caused by an imbalance between the mucosal defense and gastro-irritants, leading to gastroenteritis. Diosgenin is a steroidal sapogenin found in the wild Yam plant that has been reported with several pharmacological properties ...
Zhao Hengfang   +3 more
doaj   +1 more source

Diosgenin Determination of Costus Speciosus Water Extract Using Hplc Method [PDF]

open access: yes, 2017
Costus speciosus has been reported to have biological activity among antidiabetic, antihyperlipidemia, antioxidants. One of the chemical constituents that is responsible for some of the biological activity is diosgenin.
Sari, I. P. (Ika)   +3 more
core   +3 more sources

Diosgenin protects retinal pigment epithelial cells from inflammatory damage and oxidative stress induced by high glucose by activating AMPK/Nrf2/HO‐1 pathway

open access: yesImmunity, Inflammation and Disease, 2022
Introduction Diosgenin is a natural steroidal compound with reported antidiabetic and many other protective properties. This study aimed to explore the protective effect of diosgenin on high‐glucose (HG)‐induced retinal pigment epithelial cells.
Yang Hao, Xuefeng Gao
doaj   +1 more source

Characterization of spray dried diosgenin from fenugreek using binary blend of carrier agents

open access: yesApplied Food Research, 2022
The utilization of nutraceutical products is enhancing widely due to upcoming diseases. Consumption of bitter food is remarkably less irrespective of their health benefits.
Prajya Arya, Pradyuman Kumar
doaj   +1 more source

Optimization of diosgenin extraction from Dioscorea deltoidea tubers using response surface methodology and artificial neural network modelling.

open access: yesPLoS ONE, 2021
IntroductionDioscorea deltoidea var. deltoidea (Dioscoreaceae) is a valuable endangered plant of great medicinal and economic importance due to the presence of the bioactive compound diosgenin. In the present study, response surface methodology (RSM) and
Romaan Nazir   +7 more
doaj   +1 more source

The Equilibria of Diosgenin–Phosphatidylcholine and Diosgenin–Cholesterol in Monolayers at the Air/Water Interface [PDF]

open access: yesThe Journal of Membrane Biology, 2016
Diosgenin (Dio) has shown many treatment properties, but the most important property is cytotoxic activity in cancer cells. In this study, we investigated monolayers of Dio, cholesterol (Ch), and phosphatidylcholine (PC) at the air/water interface. The measurements were carried with a Langmuir Teflon trough and a Nima 9000 tensiometer program.
Janicka, Katarzyna   +2 more
openaire   +2 more sources

Effect of diosgenin on lipid metabolism in rats.

open access: yesJournal of Lipid Research, 1979
The purpose of this study was to determine whether diosgenin suppresses cholesterol absorption in rats, and to examine relevant changes in cholesterol and bile acid metabolism.
M N Cayen, D Dvornik
doaj   +1 more source

Pharmacokinetic Analysis of Diosgenin in Rat Plasma by a UPLC-MS/MS Approach

open access: yesJournal of Analytical Methods in Chemistry, 2022
Diosgenin, a steroidal sapogenin, has attracted attention worldwide owing to its pharmacological properties, including antitumor, cardiovascular protective, hypolipidemic, and anti-inflammatory effects.
Pei Liu   +10 more
doaj   +1 more source

Diosgenin, a Novel Aldose Reductase Inhibitor, Attenuates the Galactosemic Cataract in Rats

open access: yesJournal of Diabetes Research, 2017
Objective. To seek efficient aldose reductase inhibitors (ARIs) with excellent in vitro and in vivo biological activities against rat galactosemic cataract. Methods.
Lixia Ji, Lixia Cheng, Zhihong Yang
doaj   +1 more source

The Tuber Extract and Flour of Dioscorea Alatanormalize the Blood Lipid Profile of Rabbits Treated with High Cholesterol Diets [PDF]

open access: yes, 2014
Background: Dioscorea alata(DA) tuber has potential to prevent the condition of hyperlipidemia due to the bioactive compound, such as anthocyanins, diosgenin, and dietary fiber that beneficial in normalizing blood lipid profiles.
Imanningsih, N. (Nelis)   +4 more
core   +2 more sources

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