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The Equilibria of Diosgenin–Phosphatidylcholine and Diosgenin–Cholesterol in Monolayers at the Air/Water Interface [PDF]
The Journal of Membrane Biology, 2016 Diosgenin (Dio) has shown many treatment properties, but the most important property is cytotoxic activity in cancer cells. In this study, we investigated monolayers of Dio, cholesterol (Ch), and phosphatidylcholine (PC) at the air/water interface. The measurements were carried with a Langmuir Teflon trough and a Nima 9000 tensiometer program.
Janicka, Katarzyna +2 more
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Molecules, 2021 Although the anti-allergic and prebiotic activities of diosgenin have been reported, the influence of diosgenin on intestinal immune and epithelial cells remains unclear.
Chung-Hsiung Huang +5 more
doaj +1 more source
Diosgenin stimulation of fecal cholesterol excretion in mice is not NPC1L1 dependent
Journal of Lipid Research, 2009 Diosgenin exists in some food supplements and herbal medicines and lowers plasma cholesterol by increasing fecal cholesterol excretion. It is believed that diosgenin promotes fecal cholesterol excretion by stimulating biliary cholesterol secretion and ...
Ryan E. Temel +7 more
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BMC Complementary Medicine and Therapies, 2020 Background Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes. Diosgenin is a natural steroidal saponin with a variety of beneficial effects, including antidiabetic effects, and is a raw material for the ...
Jinhong Leng +9 more
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Cellular Physiology and Biochemistry, 2017 Background/Aims: We investigated how diosgenin, a steroidal sapogenin, has anti-tumor necrosis factor-α (TNF-α) effects in human aortic endothelial cells (HAECs).
Won Seok Yang +4 more
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Open Life Sciences, 2021 Gastric mucosal injury is caused by an imbalance between the mucosal defense and gastro-irritants, leading to gastroenteritis. Diosgenin is a steroidal sapogenin found in the wild Yam plant that has been reported with several pharmacological properties ...
Zhao Hengfang +3 more
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The role of diosgenin in crohn’s disease [PDF]
Clinical Phytoscience, 2022 AbstractInflammatory bowel disease (IBD) is a chronic idiopathic inflammation that can grossly affect the entire gastrointestinal tract (GIT) from the mouth to the anus. Crohn’s disease is the most known type of IBD and has been the focus of attention due to its increase in prevalence worldwide.
Sunday Ogundepo +9 more
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Immunity, Inflammation and Disease, 2022 Introduction Diosgenin is a natural steroidal compound with reported antidiabetic and many other protective properties. This study aimed to explore the protective effect of diosgenin on high‐glucose (HG)‐induced retinal pigment epithelial cells.
Yang Hao, Xuefeng Gao
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Characterization of spray dried diosgenin from fenugreek using binary blend of carrier agents
Applied Food Research, 2022 The utilization of nutraceutical products is enhancing widely due to upcoming diseases. Consumption of bitter food is remarkably less irrespective of their health benefits.
Prajya Arya, Pradyuman Kumar
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PLoS ONE, 2021 IntroductionDioscorea deltoidea var. deltoidea (Dioscoreaceae) is a valuable endangered plant of great medicinal and economic importance due to the presence of the bioactive compound diosgenin. In the present study, response surface methodology (RSM) and
Romaan Nazir +7 more
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