Results 41 to 50 of about 501 (137)

Comparative Transcriptome Analysis Identifies Genes Involved in Diosgenin Biosynthesis in Trigonella foenum-graecum L.

open access: yesMolecules, 2019
Trigonella foenum-graecum L. (fenugreek) is a valuable resource of producing diosgenin which serves as a substrate for synthesizing more than two hundred kinds of steroidal drugs.
Chen Zhou   +4 more
doaj   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

open access: yesPhytotherapy Research, Volume 40, Issue 8, Page 4792-4801, August 2026.
ABSTRACT The preclinical evidence for the safety of ashwagandha ( Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports. Most studies and reviews conclude
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Diosgenin biosynthesis pathway and its regulation in Dioscorea cirrhosa L. [PDF]

open access: yesPeerJ
Dioscorea cirrhosa L. (D. cirrhosa) tuber is a traditional medicinal plant that is abundant in various pharmacological substances. Although diosgenin is commonly found in many Dioscoreaceae plants, its presence in D. cirrhosa remained uncertain.
Yan Lin   +6 more
doaj   +2 more sources

Diosgenin Alleviates Age‐Related Sarcopenia by Promoting Satellite Cell Proliferation and Myogenic Differentiation via Activation of the SIRT1/PGC‐1α Signaling Pathway

open access: yesAging Cell, Volume 25, Issue 8, August 2026.
As a critical bioactive component of Polygonatum sibiricum, diosgenin improves age‐related declines in skeletal muscle mass and function by activating the SIRT1/PGC‐1α pathway, upregulating the expression of the myokine METRNL and IGF‐1, and promoting satellite cell proliferation and myogenic differentiation.
Xin Zeng   +9 more
wiley   +1 more source

Effect of Chitosan-Diosgenin Combination on Wound Healing

open access: yesInternational Journal of Molecular Sciences, 2023
The difficult-to-heal wounds continue to be a problem for modern medicine. Chitosan and diosgenin possess anti-inflammatory and antioxidant effects making them relevant substances for wound treatment. That is why this work aimed to study the effect of the combined application of chitosan and diosgenin on a mouse skin wound model.
Lubomir Petrov   +9 more
openaire   +2 more sources

High Internal Phase Pickering Emulsions as Structurally Tunable Bioinks for Extrusion‐Based Printing From 3D Fabrication to Adaptive Multiresponsive Architectures

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 4, July 2026.
ABSTRACT High internal phase Pickering emulsions (HIPPEs) have recently emerged as a versatile class of bioinks for extrusion‐based printing, offering unique opportunities for structural tunability, hierarchical architecture, and functional responsiveness.
Parham Joolaei Ahranjani   +4 more
wiley   +1 more source

Dioscorea Belizensis Lundell as A Source of Diosgenin

open access: yesJournal of Pharmacy and Pharmacology, 1963
Abstract Twenty-nine species of wild Dioscorea from British Honduras were screened for saponins. The tubers of D. belizensis Lundell afforded yields of steroids of about 2 per cent of the dry weight, calculated as the acetate of the predominant genin, diosgenin.
G, BLUNDEN, R, HARDMAN
openaire   +2 more sources

Diosgenin: Recent Highlights on Pharmacology and Analytical Methodology [PDF]

open access: yesJournal of Analytical Methods in Chemistry, 2016
Diosgenin, a steroidal sapogenin, occurs abundantly in plants such asDioscorea alata,Smilax China,andTrigonella foenum graecum. This bioactive phytochemical not only is used as an important starting material for the preparation of several steroidal drugs in the pharmaceutical industry, but has revealed also high potential and interest in the treatment ...
Mafalda Jesus   +3 more
openaire   +4 more sources

Oral administration of diosgenin protects optic nerve degeneration in a mouse model of normal-tension glaucoma

open access: yesPhytomedicine Plus
Introduction: In glaucoma, degeneration of visual pathway spread whole brain area, suggesting that restoring the degenerated axons in the whole visual pathway is crucial for vision recovery.
Chihiro Tohda, Shogo Shibue
doaj   +1 more source

Effects of Polysaccharide Elicitors from Endophytic Fusarium oxysporium Dzf17 on Growth and Diosgenin Production in Cell Suspension Culture of Dioscorea zingiberensis

open access: yesMolecules, 2011
Three polysaccharides, namely exopolysaccharide (EPS), water-extracted mycelial polysaccharide (WPS) and sodium hydroxide-extracted mycelial polysaccharide (SPS), were prepared from the endophytic fungus Fusarium oxysporium Dzf17 isolated from the ...
Ligang Zhou   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy