Results 41 to 50 of about 2,018 (130)
Pharmaceuticals, 2021 Steroidal saponins are widely used as starting precursors and medical intermediates for the semi-/total-synthesis of hundreds of steroidal drugs. One such steroidal saponin is diosgenin, which has attracted significant attention due to the huge market ...
Wancang Liu +7 more
doaj +1 more source
Megakaryocytic differentiation mechanisms in diosgenin-treated cells in relation to the SHh pathway.
, 2014 Diosgenin induced megakaryocytic differentiation in HEL cells. The SHh pathway is involved in diosgenin-induced megakaryocytic differentiation since its inhibition blocks this phenomenon.
David Yannick Leger (553347) +4 more
core +1 more source
Literature review on hepatoprotective effects of diosgenin: possible mechanisms of action [PDF]
, 2023 Liver diseases are among the major causes of death worldwide. Alcohol consumption, obesity, diabetes mellitus, viral infection, and drug-induced liver injury are common risk factors for the development of liver diseases.
Manijeh Khanmohammadi +2 more
core +1 more source
Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.A scalable, traceable workflow integrating network pharmacology, activity‐guided separation, spectrum–effect analysis, and molecular simulation identifies cryptotanshinone as a major anti–Parkinson's disease constituent of Salvia miltiorrhiza. Its neuroprotective activity is linked to stable MAO‐B interactions, restoration of ATP levels, and enhanced ...
Xin Wang +5 more
wiley +1 more source
, 2011 Introduction - Asparagus officinalis L. has several biological activities including antifungal, antiviral and antitumoral activities due to the steroidal saponins. Normally diosgenin and sarsasapogenin are analysed separately by thin-layer chromatography
Zhao, B +4 more
core +1 more source
Food Science &Nutrition, Volume 14, Issue 11, November 2026.Plantains, tubers, and roots (PTRs) represent strategic nutritional and caloric pillars for over 500 million people across tropical regions. This review evaluates traditional bioprocessing against eco‐innovative thermomechanical and non‐thermal technologies (HPP, extrusion, encapsulation) to overcome severe post‐harvest losses and antinutritional risks.
Mundéné‐Timothée Junior Lawrence +3 more
wiley +1 more source
Diosgenin does not express estrogenic activity: a uterotrophic assay
, 2014 This study assessed the effects of diosgenin on estrogenic activity using a uterotrophic assay. Immature female rats received diosgenin orally at doses of 200, 100, or 20 mg/kg body mass; and 17 alpha ethynylestradiol at doses of 1 or 0.3 mu g ...
Filipović, Branko +6 more
core +1 more source
Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle
Advanced Functional Materials, Volume 36, Issue 85, 22 October 2026.This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang +18 more
wiley +1 more source
Chemistry – A European Journal, Volume 32, Issue 37, 1 October 2026.Nitrooxylation—the installation of nitrate esters (–ONO2) has evolved from classical mixed‐acid protocols to catalytic and mechano‐, flow‐, photo‐, and electrochemical strategies. This review delineates ionic and radical manifolds for C–ONO2 bond formation, emphasizing mechanistic control, selected substrate scope, and selectivity.
Jayanta Dey, Dmitry Katayev
wiley +1 more source
Diosgenin: Ethnopharmacology, Mechanism of Actions, and Formulations [PDF]
Diosgenin, a unique steroidal saponin, offers a variety of pharmacological benefits due to its distinctive chemical structure. To fully harness its therapeutic potential, it is crucial to thoroughly understand its chemical and physical properties ...
Priyanka Singh Chaudhary
core +1 more source