Results 61 to 70 of about 5,720 (220)

Diosgenin biosynthesis pathway and its regulation in Dioscorea cirrhosa L. [PDF]

PeerJ
Dioscorea cirrhosa L. (D. cirrhosa) tuber is a traditional medicinal plant that is abundant in various pharmacological substances. Although diosgenin is commonly found in many Dioscoreaceae plants, its presence in D. cirrhosa remained uncertain.
Yan Lin, Qiuyan Hu, Qiang Ye, Haohua Zhang, Ziyu Bao, Yongping Li, Luo Jian Mo   +6 more
doaj   +2 more sources

An update on the biological and pharmacological activities of diosgenin

EXCLI journal, 2018
EXCLI Journal;Vol.
Kim, Jae Kwang, Park, Sang Un
openaire   +3 more sources

Binding of diosgenin to α-glucosidase active pocket.

, 2014
(a) Depicts docked conformation of diosgenin with yeast alpha glucosidase (3AXI.pdb), (b) hydrogen bonding and hydrophobic interactions from alpha glucosidase-diosgenin inhibitor complex.
Navanath Kumbhar (629096), Sougata Ghosh (499449), Boppana Ramanamurthy (629098), Dilip D. Dhavale (499460), Balu A. Chopade (499461), Vaishali S. Shinde (499458), Piyush More (499452), Pramod Markad (629094), Adersh Asok (629095), Ajay B. Patil (499455), Mahemud L. Shaikh (629097), Abhishek Derle (499450)   +11 more
core   +1 more source

Oral administration of diosgenin protects optic nerve degeneration in a mouse model of normal-tension glaucoma

Phytomedicine Plus
Introduction: In glaucoma, degeneration of visual pathway spread whole brain area, suggesting that restoring the degenerated axons in the whole visual pathway is crucial for vision recovery.
Chihiro Tohda, Shogo Shibue
doaj   +1 more source

Effects of Polysaccharide Elicitors from Endophytic Fusarium oxysporium Dzf17 on Growth and Diosgenin Production in Cell Suspension Culture of Dioscorea zingiberensis

Molecules, 2011
Three polysaccharides, namely exopolysaccharide (EPS), water-extracted mycelial polysaccharide (WPS) and sodium hydroxide-extracted mycelial polysaccharide (SPS), were prepared from the endophytic fungus Fusarium oxysporium Dzf17 isolated from the ...
Ligang Zhou, Shiqiong Lu, Yan Li, Peiqin Li, Jianmei Xu, Tijiang Shan, Yan Mou   +6 more
doaj   +1 more source

Tetrazine Functionalized Graphene Enables Capture of Ultra‐Low Concentrations of Biomacromolecules

Small, Volume 22, Issue 28, 18 May 2026.
A novel method for covalent modification of monolayer graphene utilizing tetrazine containing diazonium salt is demonstrated. The modified graphene bearing tetrazine moieties undergoes inverse electron demand Diels‐Alder reactions with trans‐cyclooctene‐linked molecules, enabling bioorthogonal attachment of nanobodies that selectively capture EGFP ...
Ravindra K. Gupta, Hanbin Jeong, April Goehring, Eric Gouaux, Maggie He   +4 more
wiley   +1 more source

LIN28A blocks the EndMT process of high glucose‐induced HRMECs by stabilizing SIRT6 mRNA

Journal of Diabetes Investigation, Volume 17, Issue 5, Page 739-750, May 2026.
LIN28A promotes mRNA stability of SIRT6 to activate the AMPK signaling, thereby inhibiting the EndMT process induced by HG in HRMECs. ABSTRACT Background Diabetic retinopathy (DR) is a microvascular condition resulting from microangiopathy, causing gradual retinal damage and potential blindness.
Xueying Wang, Zixu Huang, Xiaohui Kuang, Yali Nan, Zhiwen Zhang, Zongming Song   +5 more
wiley   +1 more source

Binding of diosgenin to α-amylase active pocket.

, 2014
(a) Depicts docked conformation of diosgenin with porcine pancreatic α-amylase (1OSE.pdb), (b) hydrogen bonding and hydrophobic interactions from α-amylase and diosgenin inhibitor complex.
Navanath Kumbhar (629096), Sougata Ghosh (499449), Boppana Ramanamurthy (629098), Dilip D. Dhavale (499460), Balu A. Chopade (499461), Vaishali S. Shinde (499458), Piyush More (499452), Pramod Markad (629094), Adersh Asok (629095), Ajay B. Patil (499455), Mahemud L. Shaikh (629097), Abhishek Derle (499450)   +11 more
core   +1 more source

Evaluation of Immunomodulatory activity of Diosgenin in rats

, 2018
Background: The immune system is intrinsic to health. Modulation of the immune responses to alleviate the diseases by using herbal plants has been of interest for many years. Diosgenin, a naturally occurring steroid saponin mainly present in the seeds of
Nimbalkar, Vikram V, Kadu, Urmila E, Tupe, Pratiksha N, Gaikwad, Pandurang M, Shendge, Suvarna A, Shelke, Ravina P   +5 more
core   +1 more source

Antimicrobial Effect of Spices and Their Phytochemicals: A Novel Approach to Overcoming Antibiotic Resistance

MedComm, Volume 7, Issue 4, April 2026.
This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva, Yanqi Dai, Shervanthi Homer‐Vanniasinkam, Mohan Edirisinghe   +3 more
wiley   +1 more source