Results 71 to 80 of about 2,018 (130)

Isolation and analytical diosgenin characterisation for the application of simultaneous extraction and hydrolysis from Yam in Taiwan

open access: yes, 2011
[[abstract]]To establish an RP-HPLC method for determination of diosgenin in Dioscoreae spp. for quality assessment index in Sub-project 3. The process of simultaneous ultrasonic extraction and hydrolysis for the recovery of diosgenin from Yam was ...
Lin wang-ching
core  

Structurally similar analogs of Tigogenin and Diosgenin.

open access: yes
Structurally similar analogs of Tigogenin and Diosgenin.
Sheikh Sunzid Ahmed (14802879)   +1 more
core   +1 more source

Binding of diosgenin to α-amylase active pocket.

open access: yes, 2014
(a) Depicts docked conformation of diosgenin with porcine pancreatic α-amylase (1OSE.pdb), (b) hydrogen bonding and hydrophobic interactions from α-amylase and diosgenin inhibitor complex.
Navanath Kumbhar (629096)   +11 more
core   +1 more source

Haplotype‐resolved autotetraploid genome of Dioscorea nipponica provides insights into recent polyploidization, metabolic rewiring, and environmental adaptation

open access: yesThe Plant Journal, Volume 127, Issue 6, September 2026.
SUMMARY Whole‐genome duplication (WGD, or polyploidization) is a major evolutionary force in plants, yet the genomic, transcriptional, and metabolic consequences of autopolyploidy remain less understood than those of allopolyploidy. Dioscorea nipponica, a medicinal species producing diosgenin‐type steroidal saponins, harbors both diploid and ...
Shan‐Shan Li   +8 more
wiley   +1 more source

Effects of SMO and GLI1 inhibition on diosgenin-induced megakaryocytic differentiation in HEL cells.

open access: yes, 2014
(A) Cells were transfected with siSMO or pretreated with 5µM GANT-61 for 48 h (G5) then treated with 10 µM diosgenin for 12, 24, 48, 72 and 96 h.SMO expression was evaluated by Western blot. GAPDH was used as a loading control.
David Yannick Leger (553347)   +4 more
core   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, Volume 600, Issue 15, Page 2108-2116, August 2026.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Diosgenin via NMDA Receptor Exerted Anxiolytic-like Effect on Maternally Separated Mice

open access: yes, 2021
Background and aim: Anxiety is one of the most common psychiatric disorders that lead to the disruption of daily life and also the quality of life.
Boroujeni, Shakiba Nasiri   +3 more
core  

Insights into diosgenin against inflammatory bowel disease as functional food based on network pharmacology and molecular docking

open access: yesHeliyon
Inflammatory bowel disease (IBD) is a growing global health problem. IBD is commonly prevalent in Europe and America and the incidence rate in Asia is on the rise due to altered dietary structure.
Min Cai   +5 more
doaj   +1 more source

Exploring the anti-gastric cancer mechanisms of Diosgenin through integrated network analysis, bioinformatics, single-cell sequencing, and cell experiments

open access: yesFrontiers in Pharmacology
BackgroundTo comprehensively investigate the mechanism of action of Diosgenin elements against gastric cancer (GC).MethodsTargets of Diosgenin were collected from six databases, and enrichment analysis was used to identify its associated diseases and ...
Zhangjun Yun   +9 more
doaj   +1 more source

Effects of Diosgenin on Myometrial Matrix Metalloproteinase-2 and -9 Activity and Expression in Ovariectomized Rats

open access: yesInternational Journal of Biological Sciences, 2011
Diosgenin, a traditional Yam extraction, has been used in hormone replacement for menopausal women. We aimed to investigate the influences of diosgenin administration upon the MMP-2 and -9 activity and expression and reproductive hormones of ...
Chi-Chen Chang, Tang-Ching Kuan, Yao-Yuan Hsieh, Ying-Jui Ho, Yu-Ling Sun, Chih-Sheng Lin
doaj  

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