Results 51 to 60 of about 2,018 (130)
Molecules, 2019 Trigonella foenum-graecum L. (fenugreek) is a valuable resource of producing diosgenin which serves as a substrate for synthesizing more than two hundred kinds of steroidal drugs.
Chen Zhou +4 more
doaj +1 more source
Fenugreek derived diosgenin as an emerging source for diabetic therapy [PDF]
Diabetes is a chronic metabolic disease that endangers the entire body’s tissues and organs. Diabetes impairs glucose and insulin regulation in the human body by causing pancreatic cell damage.
Manpreet Kaur +6 more
core +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.In aged rats, 6‐month SXZ treatment reversed spatial memory deficits and preserved hippocampal integrity. Mechanistic assays show that SXZ promotes glutathione metabolism and inhibits ferroptosis via p53/SLC7A11/GPX4 and Keap1/Nrf2/HO‐1 pathways. SXZ is a novel neuroprotective agent against age‐related cognitive decline.
Mengya Liu +6 more
wiley +1 more source
Diosgenin biosynthesis pathway and its regulation in Dioscorea cirrhosa L. [PDF]
PeerJDioscorea cirrhosa L. (D. cirrhosa) tuber is a traditional medicinal plant that is abundant in various pharmacological substances. Although diosgenin is commonly found in many Dioscoreaceae plants, its presence in D. cirrhosa remained uncertain.
Yan Lin +6 more
doaj +2 more sources
Ecology and Evolution, Volume 16, Issue 10, October 2026.We assembled and characterized the complete chloroplast genome of Dioscorea hypoglauca, a medicinally important yam species from southern China. The 153,219 bp genome exhibits a typical quadripartite structure, containing 129 genes (84 protein‐coding, 37 tRNA, and 8 rRNA genes), and comparative analyses with 22 other Dioscorea species revealed dynamic ...
Gang Li +5 more
wiley +1 more source
Phytomedicine PlusIntroduction: In glaucoma, degeneration of visual pathway spread whole brain area, suggesting that restoring the degenerated axons in the whole visual pathway is crucial for vision recovery.
Chihiro Tohda, Shogo Shibue
doaj +1 more source
Diosgenin, a plant steroid, induces apoptosis in human rheumatoid arthritis synoviocytes with cyclooxygenase-2 overexpression. [PDF]
, 2004 International audienceIn the present study, we have shown for the first time that a plant steroid, diosgenin, causes an inhibition of the growth of fibroblast-like synoviocytes from human rheumatoid arthritis, with apoptosis induction associated with ...
Liagre, Bertrand +9 more
core +1 more source
Brain and Behavior, Volume 16, Issue 9, September 2026.Glioblastoma (GBM) is a highly aggressive brain tumor with a poor prognosis, driven by abnormal signaling pathways that promote growth and resistance to treatment. Conventional therapies are inadequate, highlighting the need for novel multitargeted approaches.
Mehrukh Zehravi +13 more
wiley +1 more source
Molecules, 2011 Three polysaccharides, namely exopolysaccharide (EPS), water-extracted mycelial polysaccharide (WPS) and sodium hydroxide-extracted mycelial polysaccharide (SPS), were prepared from the endophytic fungus Fusarium oxysporium Dzf17 isolated from the ...
Ligang Zhou +6 more
doaj +1 more source
Diosgenin: Therapeutic Action, Pharmacology and Applications
, 2017 Diosgenin [25R-spriost-5-en-3þ-ol], is an important steroidal metabolite found in various plant species. The discovery of diosgenin has made it one of the most researched and studied herbal product.
Guruswami Gurusubramanian +5 more
core +1 more source