Results 31 to 40 of about 2,018 (130)
, 2012 Diosgenin [or (22R,25R)-spirost-5-en-3β-ol] is the starting material of the Marker degradation, a cheap semi-synthesis of progesterone, which has been designated as an International Historic Chemical Landmark.
Gabriel Guerrero-Luna +4 more
core +1 more source
Diosgenin inhibits cell proliferation of primary human thyrocytes via downregulation of PI3K/Akt signaling pathway [PDF]
, 2018 Purpose: To determine the potential influence of diosgenin on proliferation of human thyrocytes and its possible mechanism.Methods: Primary human thyrocytes were cultured and treated with diosgenin at various time intervals.
Lu, Yuxian +5 more
core +1 more source
Flavour and Fragrance Journal, EarlyView.Phytochemistry and biopotential of Melia azedarach Linn. ABSTRACT Melia azedarach Linn. (chinaberry), a medicinal plant native to tropical Asia, is a rich source of diverse bioactive compounds with reported pharmacological activities and promising therapeutic potential.
Priya Chand +3 more
wiley +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Protective Effect of Diosgenin against H2O2-Induced Oxidative Stress on H9C2 Cells [PDF]
Journal of Cell and Molecular Research, 2016 Diosgenin is an important compound in pharmaceutical industry. It has various effects such as hypocholesterolemic action or antioxidant activity in HIV infected patients. Biological oxidation pathways are involved in causing or aggravating heart disease.
Samaneh Jamshidi +5 more
doaj +1 more source
Yeast, EarlyView.We present cryoBN‐PAGE, a method that enables blue native polyacrylamide gel electrophoresis analysis of mitochondrial respiratory complexes and supercomplexes directly from whole yeast cells using cryogenic milling. This approach eliminates the need for mitochondrial isolation, reducing time and cost while preserving native protein complexes.
Lizeth J. Camacho Lopez +3 more
wiley +1 more source
Fermentation, 2023 Diosgenin, a hydrolysis product from Dioscorea plants, can be used as a precursor of steroid drugs (e.g., progesterone, testosterone, and glucocorticoid).
Fangyuan Mou +9 more
doaj +1 more source
In Vivo Protective Effects of Diosgenin against Doxorubicin-Induced Cardiotoxicity
, 2015 Doxorubicin (DOX) induces oxidative stress leading to cardiotoxicity. Diosgenin, a steroidal saponin of Dioscorea opposita, has been reported to have antioxidant activity.
Jing-Hsien Chen +4 more
core +1 more source
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
British Journal of Pharmacology, EarlyView.This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source
Transcriptome analysis of the effect of diosgenin on autoimmune thyroiditis in a rat model
Scientific Reports, 2021 In a mouse model of Graves’ disease (GD), diosgenin has been shown to have a therapeutic effect on GD by alleviating goitre. However, research on the effect of diosgenin on autoimmune thyroiditis (AIT) is lacking.
Chengfei Zhang +6 more
doaj +1 more source