Results 31 to 40 of about 5,720 (220)

Hydroxylation of Diosgenin by Absidia coerulea [PDF]

Natural Product Communications, 2010
Microbial transformation of diosgenin (1) using Absidia coerulea yielded five new polar metabolites, which were identified as (25 R)-spirost-5-en-3β,7β,12β,25α-tetrol (2), (25 S)-spirost-5-en-3β,7α,12β,25β-tetrol (3), (25 S)-spirost-5-en-3β,7β,12β,25β-tetrol (4), (25 R)-spirost-5-en-3β,7α,12β,25α-tetrol (5), and (25 R)-spirost-5-en-3β,7β,12β,24β-tetrol
Ying, Zhao, Ling-Mei, Sun, Xiao-Ning, Wang, Tao, Shen, Mei, Ji, Hong-Xiang, Lou   +5 more
openaire   +2 more sources

Effect of diosgenin on lipid metabolism in rats.

Journal of Lipid Research, 1979
The purpose of this study was to determine whether diosgenin suppresses cholesterol absorption in rats, and to examine relevant changes in cholesterol and bile acid metabolism.
M N Cayen, D Dvornik
doaj   +1 more source

Preparation Of Diosgenin-Encapsulated Microspheres By Spray Drying Technique

, 2023
Diosgenin, a naturally occurring steroid sapogenin possessing diverse therapeutic properties, represents a bioactive compound of interest. However, its complete pharmaceutical utilization has been impeded by inherent challenges, primarily associated with
Mangla, Mohit, Sanduja, Mohit, Tiwari, Ram Hari, Nayak, Amit Kumar   +3 more
core   +1 more source

Expression analysis of diosgenin pathway genes and diosgenin accumulation in fenugreek sprouts after exposure to copper sulfate

, 2022
Trigonella foenum-graecum L. is an annual herb belonging to the family Fabaceae commonly called Fenugreek. It is rich in various secondary metabolites such as alkaloids, flavonoids, phenolic compounds, and steroidal saponins.
Kim, Haeng-Hoon, Park, Byung Bae, Kwon, Do Yeon, Park, Sang Un, Sathasivam, Ramaraj, Kim, Yeon Bok   +5 more
core   +1 more source

Multi-Target Mechanisms of Moroccan Aphrodisiac Plants: An Integrative Computational and Phytochemical Investigation. [PDF]

Food Sci Nutr
Moroccan medicinal plants with in silico‐approved aphrodisiac effects provide 94 phytochemicals. Docking against PDE5, AR, ERα, and aromatase gives top scores for lutein (−10.6), baicalein (−9.5), liquiritigenin (−9.2), and procyanidins (−9.7). ADMET filtering passes baicalein and liquiritigenin but excludes lutein and procyanidins. MD simulations (200 
Elrherabi A, Khibech O, Bouhrim M, Laftouhi A, Shahat AA, Alanzi AR, Herqash RN, Basilua JM, Bnouham M.   +8 more
europepmc   +2 more sources

Diosgenin Modulates Vascular Smooth Muscle Cell Function by Regulating Cell Viability, Migration, and Calcium Homeostasis

, 2010
In this study, we compared the potencies of diosgenin, a plant-derived sapogenin structurally similar to estrogen and progesterone, on vascular smooth muscle functions ranging from contraction and migration to apoptosis.
Cornelis van Breemen, Syyong, Harley, Harley T. Syyong, Sahar Abdoli Yazdi, Navarro Dorado, Jorge, van Breemen, Cornelis, Kariminia, Amina, Boris Kuzeljevic, Jorge Navarro Dorado, Kuzeljevic, Boris, Julia T. N. Lam, Mitra Esfandiarei, Hu, Kaiji, Esfandiarei, Mitra, Abdoli Yazdi, Sahar, Kaiji Hu, Amina Kariminia, Lam, Julia   +17 more
core   +1 more source

Simultaneous Analysis of Diosgenin and Sarsasapogenin in Asparagus officinalis Byproduct by Thin-layer Chromatography

, 2011
Introduction - Asparagus officinalis L. has several biological activities including antifungal, antiviral and antitumoral activities due to the steroidal saponins. Normally diosgenin and sarsasapogenin are analysed separately by thin-layer chromatography
Zhao, B, Wang, Xiaodong, Wang, Liwei, Zhao, Bing, Yuan, Xiaofan   +4 more
core   +1 more source

A Method for Improving Microbial Conversion of Diosgenin and Separation and Identification of the Product

Fermentation, 2023
Diosgenin, a hydrolysis product from Dioscorea plants, can be used as a precursor of steroid drugs (e.g., progesterone, testosterone, and glucocorticoid).
Fangyuan Mou, Junmian Tian, Yulu Li, Shiyao Han, Ruifen Shang, Yuxin Song, Shirong Feng, Yongli Zhang, Rang Cao, Baofu Qin   +9 more
doaj   +1 more source

In vitro and in silico Evaluation of Some Natural Molecules as Potent Glutathione Reductase Inhibitors

International Journal of Secondary Metabolite, 2020
Glutathione reductase inhibitors are very popular antimalarial and anticancer agents. In this study, in vitro inhibition effects of β-sitosterol, stigmasterol, diosgenin and jervine which containing steroidal structure were determined against glutathione
Tuba Aydin
doaj   +1 more source

Protective Effect of Diosgenin against H2O2-Induced Oxidative Stress on H9C2 Cells [PDF]

Journal of Cell and Molecular Research, 2016
Diosgenin is an important compound in pharmaceutical industry. It has various effects such as hypocholesterolemic action or antioxidant activity in HIV infected patients. Biological oxidation pathways are involved in causing or aggravating heart disease.
Samaneh Jamshidi, Mehrdad Lahouti, Mohammad Taher Boroushaki, Ali Ganjeali, Ahmad Ghorbani, Mehdi Bihamta toosi   +5 more
doaj   +1 more source