Enhancement of doxorubicin efficacy by diosmetin through DNA damage accumulation and P-glycoprotein inhibition in breast cancer cells. [PDF]
Michalczyk M +7 more
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The role of venoactive compounds in the treatment of chronic venous disease. [PDF]
Gloviczki ML +4 more
europepmc +1 more source
Synergistic therapeutic approach for hemorrhoids: integrating mesenchymal stem cells with diosmin-hesperidin to target tissue edema and inflammation. [PDF]
Kusumo MHB +3 more
europepmc +1 more source
Diosmin and Coenzyme q10: Synergistic histopathological and functional protection against doxorubicin-induced hepatorenal injury in rats. [PDF]
Mansour DF +4 more
europepmc +1 more source
Targeting lon protease to inhibit persister cell formation in Salmonella Typhimurium: a drug repositioning approach. [PDF]
Narimisa N +4 more
europepmc +1 more source
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Spectroscopic and structural studies of the diosmin monohydrate and anhydrous diosmin
International Journal of Pharmaceutics, 2017Diosmin, a flavone glycoside frequently used in therapy of various veins diseases in monohydrate form, exhibits poor solubility in water and low bioavailability. Due to the fact that the anhydrous forms of drugs generally have better bioavailability than the corresponding hydrates, the aim of this study was to analyze the conversion of diosmin ...
Łukasz, Szeleszczuk +3 more
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Diosmin pretreatment affects bioavailability of metronidazole
European Journal of Clinical Pharmacology, 2003To screen for inhibitory effects of diosmin on cytochrome P(450)-mediated metabolism of metronidazole in healthy volunteers.Before/after non-blinded investigation conducted in healthy male volunteers.After an overnight fast, metronidazole (two 400-mg tablets) was administered to 12 volunteers, either alone or after a 9-day pretreatment period with a ...
K, Rajnarayana +2 more
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Diosmin for the prevention of ovarian hyperstimulation syndrome
International Journal of Gynecology & Obstetrics, 2020AbstractObjectiveTo evaluate the effect of oral diosmin on the incidence and severity of ovarian hyperstimulation syndrome (OHSS) and explore the value of diosmin in preventing and treating OHSS.MethodA retrospective study of women attending a reproductive center in Guangzhou, China, between September and December 2016.
Tingting, Li +4 more
openaire +2 more sources
Diosmin-containing phlebotropic drugs in varicose eczema
Angiology and vascular surgery, 2019The purpose of the study was to examine the effect of diosmine-based phlebotropic drugs on dynamics of regress of varicose eczema in patients with chronic venous diseases, to compare their objective complaints and subjective symptoms before and after treatment, to determine the time of improvement.The study enrolled a total of 80 patients presenting ...
D V, Rodnyansky, A A, Fokin
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