Results 191 to 200 of about 14,175 (245)

5-Hydroxymethylcytosine: a key epigenetic mark in cancer and chemotherapy response. [PDF]

Epigenetics Chromatin
Kharat SS, Sharan SK.
europepmc   +1 more source

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang, Weijiao Xu, Lei Zhao, Lin Zhong, Wendan Yu, Shengmin Wang, Lu Sun, Tao Guo, Fengzhou Li, Zhuoshi Li, Lei Fang, Shiqing Wang, Guohui Zhang, Guoqing Xue, Wei Guo, Shilei Zhao, Chundong Gu   +16 more
wiley   +1 more source

Precision synergy: IDH and PARP inhibitors as a dual-target strategy in IDH-mutant glioma treatment. [PDF]

Ann Med Surg (Lond)
Shah MH, Ranganathan S, Thomson N, Dorcas AO.   +3 more
europepmc   +1 more source

Attenuated Bacteria‐Based Tumor Therapy: Clinical Application Risks, Marketing Approval Restrictions, and Coping Strategies

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This review comprehensively overviews attenuated bacteria‐based tumor therapy, highlighting key methodologies and recent progress. It examines strategies for enhancing safety, stabilizing efficacy, optimizing manufacturing, and navigating regulatory pathways.
Yucheng Liu, Junhong Yao, Jiaxin Deng, Minjie Zhou, Kaiyue Shen, Shishuo Sun, Xiaoge Gao, Qing Zhang, Haiheng Xu   +8 more
wiley   +1 more source

Combining anti-metabolic treatments with the repurposing of eribulin for glioblastoma: a clinical opportunity? [PDF]

Transl Cancer Res
Audet-Walsh É, Galey L, Renzi S, Morin N, Hussein SMI, Richer M, Huot MÉ.   +6 more
europepmc   +1 more source

Draft genome sequence of <i>Rhodococcus rhodochrous</i> IEGM 1360 isolated from Arctic soil and able to transform oleanolic and glycyrrhetinic acids. [PDF]

Microbiol Resour Announc
Plotnitskaya NA, Ivshina IB.
europepmc   +1 more source

Role of Individual Amino Acid Residues Directly Involved in Damage Recognition in Active Demethylation by ABH2 Dioxygenase. [PDF]

Int J Mol Sci
Davletgildeeva AT, Tyugashev TE, Zhao M, Ishchenko AA, Saparbaev M, Kuznetsov NA.   +5 more
europepmc   +1 more source

Analysis of Benzoate 1,2-Dioxygenase Identifies Shared Electron Transfer Components With DxnA1A2 in Rhizorhabdus wittichii RW1. [PDF]

J Basic Microbiol
Ivanovski I, Eleya S, Zylstra GJ.
europepmc   +1 more source

Open the Rings to Close the Cycle: The Complete Degradation of Riboflavin Returns Simple Building Blocks Back to Nature. [PDF]

ACS Cent Sci
Sosa MB, Abe I.
europepmc   +1 more source

Differential effect of monoterpenes and flavonoids on the transcription of aromatic ring-hydroxylating dioxygenase genes in <i>Rhodococcus opacus</i> C1 and <i>Rhodococcus</i> sp. WAY2. [PDF]

Microb Genom
Zubrova A, Tadrosova M, Semerad J, Cajthaml T, Pajer P, Strejcek M, Suman J, Uhlik O.   +7 more
europepmc   +1 more source