A two-step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic-cell maturation [PDF]
Déborah Braun +2 more
openalex +1 more source
The return of metabolism: biochemistry and physiology of glycolysis
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning +19 more
wiley +1 more source
Beyond energy: how TCA cycle-derived metabolites regulate gene expression and inflammation in the nucleus. [PDF]
Randhawa J, Pålsson-McDermott EM.
europepmc +1 more source
Increased abscisic acid levels in transgenic tobacco over‐expressing 9 cis‐epoxycarotenoid dioxygenase influence H2O2 and NO production and antioxidant defences [PDF]
Yiming Zhang +6 more
openalex +1 more source
Integration of epigenetics into ecotoxicology: insights and fundamental research needs
ABSTRACT Epigenetics refers to heritable changes in genome function that occur without direct alterations to the DNA sequence. A multitude of environmental contaminants can influence the epigenetic marks of a genome. Changes of epigenetic marks including DNA methylation, histone modifications, and non‐coding RNAs can induce alterations at the gene ...
Albano Pinto +3 more
wiley +1 more source
TET3-overexpressing macrophages are a unifying pathogenic feature with therapeutic potential in chronic inflammatory diseases. [PDF]
Haji S, Ogawa Y.
europepmc +1 more source
The Cysteine Dioxygenase Homologue from Pseudomonas aeruginosa Is a 3-Mercaptopropionate Dioxygenase [PDF]
Egor P. Tchesnokov +8 more
openalex +1 more source
Homoharringtonine (HHT) suppresses immune evasion in acute monocytic leukaemia (AML‐M5) by attenuating the FTO/m6A/LILRB4 axis, thereby enhancing CD8+ T cell cytotoxicity. ABSTRACT Acute monocytic leukaemia, a subtype of acute myeloid leukaemia (AML), is a highly aggressive malignancy characterised by a poor prognosis, primarily due to the ability of ...
Fangfang Huang +18 more
wiley +1 more source

