Cell Biology. Clogging information flow in ALS. [PDF]
, 2014 Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a devastating neurodegenerative disorder that causes a progressive loss of motor neurons, leading to paralysis and death typically within 2 to 5 years of onset.
A. D. Gitler, J. W. Paul, Kato, Sareen
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Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents
Chemistry – A European Journal, EarlyView.This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
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Antimicrobial peptide identification using multi-scale convolutional network [PDF]
, 2019 Background: Antibiotic resistance has become an increasingly serious problem in the past decades. As an alternative choice, antimicrobial peptides (AMPs) have attracted lots of attention.
Quan, Xiongwen +4 more
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It's a Gas: Bioconjugation With Vapor‐Phase Reagents
Chemistry – A European Journal, EarlyView.Gaseous reagents are an emerging class of bioconjugation reagents that can offer alternative selectivity paradigms for the construction of precise bioconjugates. A variety of both inert and highly reactive gases have recently been developed for bioconjugation use.
Yuxuan Ding, Jun Ohata, Zachary T. Ball
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InorganicsUtilizing all-atom molecular dynamics simulations, in the current study, we examine how three different graphene-based nanosheets (pristine graphene, graphene oxide and edge-functionalized graphene) impact the self-assembly mechanism of diphenylalanine ...
Elena Markopoulou +3 more
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FREQUENCY OF DIPEPTIDES AND ANTIDIPEPTIDES
Computational and Structural Biotechnology Journal, 2013 Although it is reasonable to expect that the frequency of a generic dipeptide XY in proteins is the same of its counterpart YX, on the basis of an accurate statistical analysis of a large number of protein sequences, it appears that some dipeptides XY are considerably more frequent than their mirror images YX, referred to as antidipeptides.
openaire +4 more sources
Ion–Molecule Reaction Products as Probes and Precursors for Preparative Mass Spectrometry
Chemistry – A European Journal, EarlyView.Ion–molecule reactions in the gas phase of mass spectrometers are important for preparative mass spectrometry because they (1) provide knowledge about the intrinsic reactivity of ions, helping to predict and control their reactivity at interfaces, and (2) generate new complex ions that can be mass selected and deposited on surfaces.
Markus Rohdenburg +4 more
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Free Energies of Reaction for Aqueous Glycine Condensation Chemistry at Extreme Temperatures
Geophysical Monograph Series, Page 271-283., 2020 This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.
Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions
Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Matthew Kroonblawd, Nir Goldman
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Bioactivity in Whey Proteins Influencing Energy Balance [PDF]
, 2012 Peer-reviewedObesity develops due to energy (food) intake exceeding energy expenditure. Nutrients that reduce the positive energy balance are thus being considered as therapies to combat obesity.
Cotter, Paul D. +4 more
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Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers
Chemistry – A European Journal, EarlyView.ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda +5 more
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