Results 11 to 20 of about 38,518 (252)

Cyclic Dipeptides Formation From Linear Dipeptides Under Potentially Prebiotic Earth Conditions

open access: yesFrontiers in Chemistry, 2021
Cyclic dipeptides (DKPs) are peptide precursors and chiral catalysts in the prebiotic process. This study reports proline-containing DKPs that were spontaneously obtained from linear dipeptides under an aqueous solution. Significantly, the yields of DKPs
Yeting Guo   +15 more
doaj   +3 more sources

Fine‐Tuning Supramolecular Assemblies by Controlling Micellar Aggregates

open access: yesMacromolecular Materials and Engineering, 2023
Supramolecular assembly can be used to fabricate complex functional materials by organizing simple building blocks. However, it is difficult to control the hierarchical assembly across multiple length scales.
Dipankar Ghosh   +7 more
doaj   +1 more source

The Synthesis of (2R)-Aziridine-2-carboxylic Acid Containing Dipeptides

open access: yesActa Chimica Slovenica, 2022
Optimized conditions for the synthesis of fully deprotected (2R)-aziridine containing dipeptides are described. Preparation of fully protected N- and C- terminal aziridine containing dipeptides was found to be straightforward and high yielding for the ...
Samo Kuzmič, Martina Hrast, Rok Frlan
doaj   +1 more source

Feedback Regulation of Cathepsin C by the Propeptide Dipeptides of Granzymes A and B

open access: yesActa Chimica Slovenica, 2019
Granzymes A and B are activated by proteolytic removal of their N-terminal dipeptides by cathepsin C (dipeptidyl-peptidase I). However, the possible physiological role of the cleaved dipeptides Glu-Lys and Gly-Glu is not yet understood.
Janja Božič, Iztok Dolenc
doaj   +1 more source

Dipeptides Containing Pyrene and Modified Photochemically Reactive Tyrosine: Noncovalent and Covalent Binding to Polynucleotides

open access: yesMolecules, 2023
Dipeptides 1 and 2 were synthesized from unnatural amino acids containing pyrene as a fluorescent label and polynucleotide binding unit, and modified tyrosine as a photochemically reactive unit.
Igor Sviben   +6 more
doaj   +1 more source

Neighbouring residue effects on the ^(15)N chemical shifts of some aliphatic dipeptides [PDF]

open access: yes, 1975
The ^(15)N chemical shifts of a number of simple aliphatic dipeptides have been determined in a aqueous solution and while the amine nitrogen shift is independent of the nature of the neighbouring residue, the peptide nitrogen shift shows a marked ...
Loftus, Philip   +3 more
core   +1 more source

Density Functional Studies on Secondary Amides: Role of Steric Factors in Cis/Trans Isomerization

open access: yesMolecules, 2018
Cis/trans isomerization of amide bonds is a key step in a wide range of biological and synthetic processes. Occurring through C-N amide bond rotation, it also coincides with the activation of amides in enzymatic hydrolysis.
Balmukund S. Thakkar   +2 more
doaj   +1 more source

Aqueous Amino Acids and Proteins Near the Surface of Gold in Hydrophilic and Hydrophobic Force Fields [PDF]

open access: yes, 2014
We calculate potentials of the mean force for twenty amino acids in the vicinity of the (111) surface of gold, for several dipeptides, and for some analogs of the side chains, using molecular dynamics simulations and the umbrella sampling method.
Cieplak, Marek, Nawrocki, Grzegorz
core   +1 more source

Schistosome dipeptide of love

open access: yesTrends in Parasitology, 2022
The female schistosome's dependence on the male to reach sexual maturity has puzzled scientists for decades. Using various molecular techniques, Chen et al. dissect the synthesis pathway of the β-alanyl-tryptamine dipeptide (BATT), emitted by the male into its environment, which induces sexual maturation and egg-laying in the female.
Yohann Le Govic   +2 more
openaire   +4 more sources

The New Dipeptide TSPO Ligands: Design, Synthesis and Structure–Anxiolytic Activity Relationship

open access: yesMolecules, 2020
The translocator protein (TSPO, 18 kDa) plays an important role in the synthesis of neurosteroids by promoting the transport of cholesterol from the outer to the inner mitochondrial membrane, which is the rate-limiting step in neurosteroidogenesis ...
Tatiana A. Gudasheva   +6 more
doaj   +1 more source

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