Results 71 to 80 of about 28,724 (253)

Ion–Molecule Reaction Products as Probes and Precursors for Preparative Mass Spectrometry

Chemistry – A European Journal, EarlyView.
Ion–molecule reactions in the gas phase of mass spectrometers are important for preparative mass spectrometry because they (1) provide knowledge about the intrinsic reactivity of ions, helping to predict and control their reactivity at interfaces, and (2) generate new complex ions that can be mass selected and deposited on surfaces.
Markus Rohdenburg, Sebastian Kawa, Kay‐Antonio Behrend, Harald Knorke, Jonas Warneke   +4 more
wiley   +1 more source

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

Cytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius, Ezekiel C. Thomas, Erik H. Collet, Erin Jenson, Chad G. Pearson, Ryoma Ohi, Kristen J. Verhey   +6 more
wiley   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Host–microbiota interaction drives 5‐hydroxyindole‐3‐acetic acid production to promote linear growth in infant mice

iMetaOmics, EarlyView.
This study discovered that Lactiplantibacillus plantarum Hi188 promoted linear growth in postweaning mice. Transcriptomic analysis, untargeted metabolomics, and in vitro experiments showed that the elevated levels of 5‐hydroxyindole‐3‐acetic acid (5‐HIAA) activated the hepatic aryl hydrocarbon receptor (AhR) and subsequently promoted insulin‐like ...
Yongmei Yang, Jing Yang, Weiyao Zhang, Linghao Zhou, Chenxu Zhu, Xuguang Zhang, Yuejian Mao, Meiling Zhang   +7 more
wiley   +1 more source

Employing Molecular Dynamics Simulations to Explore the Behavior of Diphenylalanine Dipeptides in Graphene-Based Nanocomposite Systems

Inorganics
Utilizing all-atom molecular dynamics simulations, in the current study, we examine how three different graphene-based nanosheets (pristine graphene, graphene oxide and edge-functionalized graphene) impact the self-assembly mechanism of diphenylalanine ...
Elena Markopoulou, Panagiotis Nikolakis, Gregory Savvakis, Anastassia N. Rissanou   +3 more
doaj   +1 more source

FREQUENCY OF DIPEPTIDES AND ANTIDIPEPTIDES

Computational and Structural Biotechnology Journal, 2013
Although it is reasonable to expect that the frequency of a generic dipeptide XY in proteins is the same of its counterpart YX, on the basis of an accurate statistical analysis of a large number of protein sequences, it appears that some dipeptides XY are considerably more frequent than their mirror images YX, referred to as antidipeptides.
openaire   +4 more sources

A personal 360° view of applications of ‘biomimetic’ molecular recognition

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley   +1 more source

Synthesis of Telechelic‐Type Polypeptides Functionalized with Aromatic Units and the Characterization of Their Structures and Thermal Properties

Macromolecular Rapid Communications, EarlyView.
Polypeptide chains were extended from both ends of aromatic diamines by chemoenzymatic polymerization, resulting in the synthesis of telechelic polyglycines (TPG) and polyalanines (TPA). These telechelic polymers assembled into branched nanofibrils through π‐π stacking of aromatic rings, with the polymer backbones bent at the aromatic unit.
Yusuke Ueno, Kousuke Tsuchiya, Hiroyasu Masunaga, Keiji Numata   +3 more
wiley   +1 more source

Latex Serum‐Derived Supramolecular Networks Enable Toughening of Natural Rubber

Macromolecular Rapid Communications, EarlyView.
Latex‐serum addition enhances strain‐induced crystallization (SIC) toughening in natural rubber, increasing tearing strength and extending the SIC activation window. Supramolecular networks form via bifurcated hydrogen bonding between polyol components (e.g., quebrachitol) and end‐functionalized polyisoprene chains, serving as effective crystallization
Katsuhiko Tsunoda, Mayank Dixit, Yasuhiro Shoda, Yuji Kitamura, Takashi Taniguchi, Kenji Urayama   +5 more
wiley   +1 more source

Structure–Activity Prediction of ACE Inhibitory/Bitter Dipeptides—A Chemometric Approach Based on Stepwise Regression

Molecules, 2019
Forward and backward stepwise regression (FR and BR, respectively) was applied for the structure–bioactivity prediction of angiotensin converting enzyme (ACE)-inhibitory/bitter-tasting dipeptides.
Monika Hrynkiewicz, Anna Iwaniak, Justyna Bucholska, Piotr Minkiewicz, Małgorzata Darewicz   +4 more
doaj   +1 more source