Results 91 to 100 of about 21,027 (334)

Diammonium tris­[hexa­aqua­magnesium(II)] tetra­kis­[hydrogenphosphate(III)], (NH4)2[Mg(H2O)6]3(HPO3)4 [PDF]

, 2005
The framework of the title compound is made up of discrete Mg(H2O)6 octa¬hedra, and HPO3 and NH4 tetra¬hedra, which are organized in planes parallel to (010). Strong hydrogen bonding between the building units stabilizes the structure.
Capitelli, Francesco, El Bali, Brahim, Lachkar, Mohammed, Messouri, Ibtissam, Piniella, J. Francesc, Slimani, Zineb   +5 more
core   +2 more sources

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

Advanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang, Shenghui Wang, Mengyuan Cao, Lulu Wang, Wei Jiang, Xiyun Yan, Ying Liu, Bing Jiang   +7 more
wiley   +1 more source

Biological functions and clinical implications of the CMPK2 across multisystemic diseases

Cell & Bioscience
Cytidine/Uridine monophosphate kinase 2 (CMPK2) is a crucial enzyme responsible for the phosphorylation of nucleotides, specifically converting cytidine monophosphate (CMP) and uridine monophosphate (UMP) into their respective diphosphates, known as ...
Jia Li, Qing Liu, Jie Yang, Ziyi Yang, Mingxin Zhang, Jie Zhang, Chao Sun   +6 more
doaj   +1 more source

Spd2 assists Spd1 in modulation of RNR architecture but does not regulate deoxynucleotide pools [PDF]

, 2014
In yeasts, small intrinsically disordered proteins (IDPs) modulate ribonucleotide reductase (RNR) activity to ensure an optimal supply of dNTPs for DNA synthesis. The S. pombe Spd1 protein can directly inhibit the large RNR subunit (R1), import the small
Basrai, Beck, Bester, Bähler, Chabes, Danielsson, Elledge, Fairman, Fleck, Halazonetis, Hofer, Holmberg, Holmberg, Håkansson, Kjaerulff, Knutsen, Lee, Liu, Liu, Marguerat, Maundrell, Moreno, Moss, Nestoras, Nielsen, Nordlund, Reichard, Rhind, Salguero, Tompa, Uchiki, Weinberg, Woollard, Wu, Yoshida, Zhao, Zhao, Zolezzi   +37 more
core   +1 more source

Rescuing Mitochondrial Dysfunction in Macrophages Prevents Osteonecrosis of the Jaw in Anti‐Resorptive Therapy

Advanced Science, EarlyView.
Schematic model showing the suggested mechanism that ZA induces classical activation of macrophages by impairing mitochondrial biofunction and inhibiting mitochondrial clearance to contribute to the pathological process of BRONJ. RAPA‐loaded nanoparticles ZDPR has shown potential in alleviating BRONJ lesions as well as treating osteoporosis or ...
Hang Zhang, Xin Shen, Haiyang Liu, Xinxi Yuan, Mumin Cao, Xuepeng Lv, Ziji Ling, Songsong Guo, Rongyao Xu, Xiang Li, Hongbing Jiang   +10 more
wiley   +1 more source

Optical detection of di- and triphosphate anions with mixed monolayer-protected gold nanoparticles containing zinc(II)–dipicolylamine complexes

Beilstein Journal of Organic Chemistry, 2020
Gold nanoparticles covered with a mixture of ligands of which one type contains solubilizing triethylene glycol residues and the other peripheral zinc(II)–dipicolylamine (DPA) complexes allowed the optical detection of hydrogenphosphate, diphosphate, and
Lena Reinke, Julia Bartl, Marcus Koch, Stefan Kubik   +3 more
doaj   +1 more source

The relation of polynucleotide phosphorylase and growth of Escherichia coli [PDF]

, 1968
Call number: LD2668 .T4 1968 C443Master of ...
Chen, Amy H. M.
core  

Syndromes associated with mitochondrial DNA depletion [PDF]

, 2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution License.Mitochondrial dysfunction accounts for a large group of inherited metabolic disorders most of which are due to a dysfunctional mitochondrial ...
Almeida, Ligia S., Nesti, C., Nogueira, Célia, Pezzini, I., Santorelli, F.M., Videira, A., Vilarinh, Laura   +6 more
core   +1 more source

Pan2‐Pan3 Complex‐Mediated Deadenylation Enforces mRNA Quality Control for Infection of the Rice Blast Fungus

Advanced Science, EarlyView.
Discovery that deadenylation, rather than transcription, acts as the rate‐limiting step for developmental timing in a plant pathogen. Evidence that P‐body integrity and mRNA decay are mechanistically coupled to rapid cellular differentiation under environmental stress. Identification of Pan2‐Pan3 as a pathogen‐specific “meta‐virulence factor” absent in
Ziwei Lv, Junting Feng, Shenxian Zhou, Zhiguang Qu, Jun Peng, Xiao‐Lin Chen, Deng Chen   +6 more
wiley   +1 more source

Functional mechanistic diversity of the NUDIX effectors in fungal pathogens

Phytopathology Research
NUcleoside Diphosphate-linked to moiety X (NUDIX) hydrolases are ubiquitous enzymes that maintain metabolic homeostasis by hydrolyzing potentially toxic nucleoside diphosphates.
Vijai Bhadauria, Guangjun Li
doaj   +1 more source