Recent Progress on Giant Molecules: Synthesis, Assembly, and Applications
Chemistry–Methods, Volume 6, Issue 3, March 2026.Giant molecules are molecules constructed by molecular nanoparticles with precise, rigid structure, have similar structures with small molecules and a large size as macromolecules. In this review, the constituent modules of giant molecules, as well as their synthesis, self‐assembly, applications in various fields and future developing prospect are ...
Haoyu Chen +7 more
wiley +1 more source
Sulfur Ylides in Skeletal‐Editing—Ring Expansion Reactions
Helvetica Chimica Acta, Volume 109, Issue 3, March 2026.Sulfur ylides (S‐ylides) are emergent diazo surrogates that enable skeletal editing and ring expansion with safer handling and broad functional group tolerance. This perspective covers pioneer works and highlights recent advances in the field, while outlining key challenges and future directions that may redefine the role of S‐ylides in modern ...
Arsala Kamal +3 more
wiley +1 more source
Synthesis and 1,3-Dipolar Cycloaddition Reactions of Chiral Maleimides
Molecules, 1997 New routes to the synthesis of various novel chiral maleimides are described. The oxabicyclic anhydride 2 readily available exo-Diels-Alder adduct of furan and maleic anhydride was used as a vehicle, which in turn reacted with hydrochlorides of amino ...
Lubor Fisera, Vladimir Ondrus
doaj +1 more source
Bioorthogonal metal-free click-ligation of cRGD-pentapeptide to alginate [PDF]
, 2012 Click reactions have become very common and powerful ligation techniques, of which 1,3-dipolar cycloadditions have most frequently been employed. Since metal-mediated cycloadditions are incompatible in biomedical applications due to toxicity issues ...
Dräger, Gerald +2 more
core +2 more sources
T‐Shaped 8‐Aryl(ethynyl)‐Substituted Psoralens With Tunable Charge‐Transfer Absorption
European Journal of Organic Chemistry, Volume 29, Issue 8, 25 February 2026.Starting from 8‐methoxypsoralen, new 8‐arylated and 8‐alkynylated psoralen derivatives are accessible by cross‐coupling. These T‐shaped π‐expanded chromophores are luminescent and photophysics reveal a highly polar excited state with tunable charge‐transfer character.
Lena T. Leusch, Thomas J. J. Müller
wiley +1 more source
ChemistryOpen, 2020 1,2,4‐Oxadiazole[4,5‐a]piridinium salts add alcohols and alkoxides to undergo electrocyclic ring opening affording alkoxybutadienyl 1,2,4‐oxadiazole derivatives.
Dr. Mattia Moiola +2 more
doaj +1 more source
Enantioselective 1,3-Dipolar Cycloadditions of α-Methylene Lactams to Construct Spirocycles. [PDF]
Org Lett, 2023 Nishiura Y +3 more
europepmc +1 more source
Binap-silver-catalyzed enantioselective multicomponent 1,3-dipolar cycloaddition of azomethines ylides derived from ethyl glyoxylate [PDF]
, 2015 The enantioselective binap–silver catalyzed multicomponent 1,3-dipolar cycloaddition using ethyl glyoxylate, phenylalanine ethyl ester, and maleimides is described. The employment of basic silver carbonate allows the reaction to take place in the absence
Mancebo Aracil, Juan +2 more
core +2 more sources
A combined experimental and theoretical study of the polar [3+2] cycloaddition of electrophilically activated carbonyl ylides with aldehydes and imines [PDF]
, 2009 International audienceNumerous 2,5-diaryl-1,3-dioxolane-4,4-dicarbonitriles and 2,4-diphenyl-1,3-oxazolidine-5,5- dicarbonitriles have been synthesized by [3+2] cycloaddition reactions between carbonyl ylides generated from epoxides, and aldehydes or ...
Bentabed-Ababsa, Ghenia +7 more
core +3 more sources
An Overlooked Pathway in 1,3-Dipolar Cycloadditions of Diazoalkanes with Enamines. [PDF]
Angew Chem Int Ed Engl, 2022 Li L +5 more
europepmc +1 more source