Results 71 to 80 of about 3,577 (190)

Structural‐to‐Functional Complexity Transformations Enabled by Bridged Polyheterocycles: Access to Cis‐1,3‐Diamines and Amino‐Alcohols

open access: yesChemistryEurope, Volume 4, Issue 6, June 2026.
Polycyclic intermediates enable stereocontrolled synthesis of densely functionalized cis‐1,3‐diamine and amino alcohol carbocycles and heterocycles via structural‐to‐functional complexity transformations from low‐complexity starting material. Cis‐1,3‐functionalized carbocycles and saturated heterocycles are ubiquitous motifs in natural products ...
Jiayi Zhu   +2 more
wiley   +1 more source

1,3-Dipolar Cycloadditions of N-Benzyl Furfuryl Nitrones with Electron-rich Alkenes

open access: yesMolecules, 2000
The 1,3-dipolar cycloaddition reaction of N-benzyl-C-(2-furyl)nitrones with electron-rich alkenes gives preferentially trans-substituted 3,5-disubstituted isoxazolidines (endo approach).
Tomas Tejero   +3 more
doaj   +1 more source

Soft Ferroelectrics in One Dimension: Ferroelectric Columnar Liquid Crystals

open access: yesChemPlusChem, Volume 91, Issue 6, June 2026.
Helical ferroelectric columnar liquid crystals (FCLCs) confine bistable axial polarization within individual columns. An electric field reversibly flips the macrodipole, enabling two nonvolatile states readable as “0” and “1.” This Cconcept highlights supramolecular locking and helical architectures that deliver genuine switching and long‐lived zero ...
Seongwon Park, Byoung‐Ki Cho
wiley   +1 more source

The Dithiirane–Thiosulfine Equilibrium Revisited—A Computational Study of Structure, Thermodynamics and Kinetics

open access: yesJournal of Physical Organic Chemistry, Volume 39, Issue 6, June 2026.
The dithiirane–thiosulfine equilibrium has been revisited by means of modern computational chemistry tools to shed light on whether stable thiosulfines might be isolated. ABSTRACT Thiosulfines as reactive S‐centered 1,3‐dipoles undergoing (3 + 2)‐cycloadditions are still of interest in the chemistry of sulfur‐rich heterocycles.
Dirk Buddensiek, Thomas Behrens
wiley   +1 more source

Deciphering the properties and reaction mechanism of anhydromevalonate phosphate decarboxylase, a prenylated flavin mononucleotide‐dependent enzyme in the archaeal mevalonate pathway

open access: yesThe FEBS Journal, Volume 293, Issue 11, Page 3303-3319, June 2026.
Characterization of anhydromevalonate phosphate decarboxylase, the UbiD‐family decarboxylase involved in the archaeal mevalonate pathway, was conducted. The enzyme is responsible for the biosynthesis of isoprenoids, such as archaeal membrane lipids, respiratory quinones, and dolichols.
Rino Ishikawa   +9 more
wiley   +1 more source

Applications of Azide-Based Bioorthogonal Click Chemistry in Glycobiology

open access: yesMolecules, 2013
Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments.
Xiu Zhang, Yan Zhang
doaj   +1 more source

Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 19, 22 May 2026.
Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley   +1 more source

Stereoselective intramolecular 1,3-dipolar cycloadditions

open access: yes, 2001
An in depth account of intramolecular 1,3-dipolar cycloadditions involving dipoles such as nitrile oxides, silyl nitronates, H-nitrones, azides, and nitrilimines is presented with particular emphasis on the stereochemistry during the cyclo addition ...
HASSNER, A, NAMBOOTHIRI, INN
core  

1,2‐Diazetidines − Structure, Synthesis, and Functionalization

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 19, 22 May 2026.
1,2‐Diazetidines are saturated four‐membered heterocycles featuring two adjacent nitrogen atoms. Despite recent advances in their synthesis and promising potential in medicinal chemistry, the chemistry of these cyclic hydrazines remains underexplored.
Stefan Roesner
wiley   +1 more source

Synthesis and 1,3-Dipolar Cycloaddition Reactions of Chiral Maleimides

open access: yesMolecules, 1997
New routes to the synthesis of various novel chiral maleimides are described. The oxabicyclic anhydride 2 readily available exo-Diels-Alder adduct of furan and maleic anhydride was used as a vehicle, which in turn reacted with hydrochlorides of amino ...
Lubor Fisera, Vladimir Ondrus
doaj   +1 more source

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