Results 61 to 70 of about 1,577 (174)

Reaction Enumeration Based on NBO‐Informed Molecular Graphs

open access: yesJournal of Computational Chemistry, Volume 47, Issue 19, 15 July 2026.
NBO‐informed molecular graphs represent chemistry via valence orbitals rather than atomic connectivity, enabling consistent reaction analysis across environments. By identifying delocalized motifs and increasing complexity adaptively, the framework enables efficient exploration of inaccessible mechanisms and diverse catalytic and reaction networks for ...
Javier E. Alfonso‐Ramos, Thijs Stuyver
wiley   +1 more source

Synthesis and 1,3-Dipolar Cycloaddition Reactions of Chiral Maleimides

open access: yesMolecules, 1997
New routes to the synthesis of various novel chiral maleimides are described. The oxabicyclic anhydride 2 readily available exo-Diels-Alder adduct of furan and maleic anhydride was used as a vehicle, which in turn reacted with hydrochlorides of amino ...
Lubor Fisera, Vladimir Ondrus
doaj   +1 more source

Reactions of 1,2,4‐Oxadiazole[4,5‐a]piridinium Salts with Alcohols: the Synthesis of Alkoxybutadienyl 1,2,4‐Oxadiazoles

open access: yesChemistryOpen, 2020
1,2,4‐Oxadiazole[4,5‐a]piridinium salts add alcohols and alkoxides to undergo electrocyclic ring opening affording alkoxybutadienyl 1,2,4‐oxadiazole derivatives.
Dr. Mattia Moiola   +2 more
doaj   +1 more source

Oligonucleotides Post‐Synthetic Modifications: An Overview of Clickable Nucleoside Phosphoramidites Suitable for Solid‐Phase Synthesis

open access: yesChemBioChem, Volume 27, Issue 13, 14 July 2026.
Clickable nucleoside phosphoramidites can be incorporated into oligonucleotides via solid‐phase synthesis (SPOS), enabling rapid and site‐specific post‐functionalization using bioorthogonal reactions. This review highlights their design, synthetic accessibility, and SPOS incorporation requirements, along with the kinetics and efficiency of post ...
Sébastien Depienne   +3 more
wiley   +1 more source

A Modular Synthesis of Isoindole/Indolizine Hybrids via the 1,3‐Dipolar Cycloaddition of Pyridine‐Based Mesoionics with Benzyne

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 26, 13 July 2026.
An approach to prepare pyrido[2,1‐a]isoindoles via the cycloaddition of pyridine‐based 1,3‐dipoles and benzyne is described, offering modular access to a range of substituted products by systematic tuning of the dipole. A modular strategy for the synthesis of fused indolizine/isoindole hybrids, pyrido[2,1‐α]isoindoles, via cycloaddition of pyridine ...
Samira Taghizadeh Nodehi   +2 more
wiley   +1 more source

Monosubstituted N‐Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds

open access: yesChemistry – A European Journal, Volume 32, Issue 26, 11 July 2026.
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis   +2 more
wiley   +1 more source

An Overlooked Pathway in 1,3-Dipolar Cycloadditions of Diazoalkanes with Enamines. [PDF]

open access: yesAngew Chem Int Ed Engl, 2022
Li L   +5 more
europepmc   +1 more source

Dynamic Catalytic Highly Enantioselective 1,3-Dipolar Cycloadditions. [PDF]

open access: yesAngew Chem Int Ed Engl, 2021
Yildirim O   +5 more
europepmc   +1 more source

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