Results 101 to 110 of about 3,844,628 (256)

Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini, Giulia Tammam, Andra Ezaru, Manuela Gambella, Benoît Sanson, Luisa Villa, Michele Cavalli, Mihai‐Bogdan Ioncea, Angela Puma, Sabrina Sacconi   +9 more
wiley   +1 more source

Hepatitis C Virus Infection and Renal Disorders

Journal of Renal and Hepatic Disorders, 2019
Hepatitis C virus (HCV) infection is frequently associated with extrahepatic disorders, among which renal diseases are frequent. This article highlights the most frequent HCV-associated renal disorders, the impact of HCV infection on chronic renal ...
Maurizio Salvadori, Aris Tsalouchos
doaj   +1 more source

Tamoxifen-induced hepatotoxicity caused by drug interaction with direct-acting antiviral agents for hepatitis C.

, 2019
A 68-year-old man develops acute hepatocellular injury during treatment with direct-acting antiviral agents (DAA) for hepatitis C. Medical history reveals the intake of tamoxifen as adjuvant treatment for breast cancer, currently in remission.
Wyffels, Klara, Horsmans, Yves
core   +1 more source

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

Availability of hepatitis C diagnostics and therapeutics in European and Eurasia countries

, 2021
Background. Treatment with direct acting antiviral agents (DAAs) has provided sustained virological response rates in > 95% of patients with chronic hepatitis C virus (HCV) infection.
Salmon, Dominique, Puca, Edmond, Boesecke, Christoph, Bayramli, Ramin, Arends, Joop E., Ahmeti, Salih, Kilani, Badreddine, SÜNBÜL, MUSTAFA, Maticic, Mojca, Vince, Adriana, Pinede, Juan A., Husa, Petr, Tsertswadze, Tengiz, Ustianowski, Andrew, Lazarevic, Ivana, Leblebicioglu, Hakan, Gervain, Judit, Abuova, Gulzhan, Negro, Francesco, Koulentaki, Mairi, Corti, Giampaolo, Duberg, Ann-Sofi, Salkic, Nermin N., Ruta, Simona, Pshenichnaya, Natalia Yurievna, Ozaras, Resat, Santos, Lurdes   +26 more
core   +1 more source

Tailored Cationic Visible‐Light‐Active Interfaces for Sustainable, Biodegradable Nanofibers With Dual‐Mode Antimicrobial Activity and Robust Electrostatic Particle Capture

Advanced Materials, EarlyView.
Surface co‐functionalization of biodegradable nanofibers with sodium copper chlorophyllin and quaternary ammonium compounds achieves synergistic antimicrobial activity through combined photodynamic and contact‐killing mechanisms. The cationic surface provides humidity‐resistant electrostatic particle capture while maintaining rapid enzymatic ...
Dong Uk Lee, Jae Hak Shin, Seung Yeon Lee, In Ho Kim, Jiho Choi, Joon Young Park, Sang Bok Kim, Jeong Sang Son, Sang Hun Kim, Jae Hee Jung, Dong Yun Choi   +10 more
wiley   +1 more source

Five-Year Allograft Survival for Recipients of Kidney Transplants From Hepatitis C Virus Infected vs Uninfected Deceased Donors in the Direct-Acting Antiviral Therapy Era

, 2022
This cohort study examines the validity of the Kidney Donor Profile Index’s hepatitis C virus (HCV) penalty during the direct-acting antiviral era by comparing 5-year allograft survival between recipients of kidneys from HCV-RNA–positive donors vs HCV ...
Potluri, Vishnu S., Goldberg, David S., Reese, Peter P., Abt, Peter L., Tran, Amelia H., Schaubel, Douglas E.   +5 more
core   +1 more source

Antibody‐Precomplexed Hemagglutinin Constructs Multivalently Bind Sialylated Glycan Receptors with Variable Valencies

Advanced Materials Interfaces, EarlyView.
Hemagglutinin precomplexation with antibodies (Abs) results in broad valency distributions, though it increases the total avidity from mM to nM to high nM. The valency distribution and the orientation of multivalent HA‐Ab complexes determine the extent of binding to different types of assays, whether the receptors are displayed in 2D or 3D.
Daniel Y. E. L. Tambuwun, María Ríos Carrasco, Elif Uslu, Geert‐Jan P. H. Boons, Nadia J. Mokiem, Albert J. R. Heck, Victor C. Yin, Robert P. de Vries, Jurriaan Huskens   +8 more
wiley   +1 more source

Direct-Acting Antiviral Agents in Prevention of Maternal–Fetal Transmission of Hepatitis C Virus in Pregnancy

Pathogens
Prior to the Food and Drug Administration approval of ledipaspavir/sofosbuvir (Harvoni®) in 2014, the treatment of hepatitis C was interferon plus or minus ribavirin.
Christopher Hartley, Trung Van, Wikrom Karnsakul   +2 more
doaj   +1 more source

Direct-acting antiviral in the treatment of hepatitis c virus: a review of pharmacology and clinical application

, 2017
HCV is a global public health issue with millions people affected around the world. Chronic HCV infection can lead to severe long-term consequences like cirrhosis, liver cancer and liver failure.
Trinh, GiaKhanh
core