Results 91 to 100 of about 26,182 (278)
Monosaccharide and Disaccharide Mimics: New Molecular Tools for Biology and Medicine
CHIMIA, 2001 Intercellular communication is governed by interactions between surface oligosaccharides and glycoproteins. The biosynthesis of these molecules involves glycosidations catalyzed by glycosyltransferases and hydrolysis of O-glycosyl linkages ...
Pierre Vogel
doaj
Chemistry – A European Journal, EarlyView.We designed and synthesized novel mannose‐6‐phosphate (M6P) derivatives to enhance their binding affinity for the CI‐M6P/IGF2 receptor, which plays a key role in lysosomal targeting. Using a fluorescence polarization assay, we evaluated di‐, tri‐, and penta‐M6P peptides and modified M6P analogs.
Lucie Mrázková +11 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.The convergent synthesis of Lewis‐X‐containing betulinic acid and echinocystic acid saponins (1 and 2) is presented. The synthetic saponins were shown to inhibit, at the low micromolar range, the DC‐SIGN‐ and L‐SIGN‐mediated transfer of HIV‐1 infection to CD4‐positive cells, whereas free Lewis‐X, aglycones, and structurally similar triterpenoid ...
Oscar Javier Gamboa Marin +5 more
wiley +1 more source
Theoretical and NMR-based Conformational Analysis of Phosphodiester-linked Disaccharides
Scientific Reports, 2017 The conformational behaviour of three phosphate-bridged dimannosides was studied by means of NMR and computational molecular modelling. First, the conformations of the phosphodiester linker were determined by quantum chemistry methods using dimethyl ...
Alexey G. Gerbst +5 more
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The Synthesis of Aryl‐β‐C‐Glycosides from Native Saccharides
Chemistry – A European Journal, Accepted Article.The synthesis of p‐nitrophenol‐β‐C‐glycosides from native mono‐, di‐ and trisaccharides is described. The one‐pot‐two‐step procedure uses water as the solvent and produces exclusively β‐C‐glycosides, the desired stereochemistry for most medicinal chemistry applications.
Daan V. Bunt +5 more
wiley +1 more source
Differentiation of Disaccharide-splitting Enzymes [PDF]
, 1939 J. Leibowitz, S. Hestrin
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ChemMedChem, EarlyView.Boron Neutron Capture Therapy is a promising technique for treating “untreatable” brain cancers by having 10B nuclei absorb neutrons and then decay to 7Li destroying the cells they are in. The dominant clinical agent is 4‐borono‐l‐phenylalanine, and this review comprehensively analyzes all of its reported patent and literature syntheses to help ...
Sarfraz Ahmad +5 more
wiley +1 more source
Comparison of various carbohydrates for hydrogen production in microbial electrolysis cells
Biotechnology & Biotechnological Equipment, 2016 The direct production of hydrogen from various carbohydrates of lignocellulosic biomass is examined by using single-chamber membrane-free microbial electrolysis cells.
Tunc Catal
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Substitution Pattern of the Secondary Rim of ICyD Ligand Influences Stereoselectivity
European Journal of Organic Chemistry, Volume 28, Issue 12, March 24, 2025.The substitution pattern of the secondary rim in NHC‐capped cyclodextrin gold complexes significantly influences the reactivity and stereoselectivity of gold‐catalyzed enyne cycloisomerizations. A custom‐designed benzyl‐methyl substitution pattern delivers the highest yields and selectivities.
Guangcan Xu +6 more
wiley +1 more source
HUMAN INTESTINAL DISACCHARIDASES AND HEREDITARY DISACCHARIDE INTOLERANCE. THE HYDROLYSIS OF SUCROSE, ISOMALTOSE, PALATINOSE (ISOMALTULOSE), AND A 1,6-α-OLIGOSACCHARIDE (ISOMALTO-OLIGOSACCHARIDE) PREPARATION* [PDF]
, 1963 Arne Dahlqvist +3 more
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