Results 111 to 120 of about 31,873 (244)

Liquid Phase Backscattered Scanning Electron Microscopy of Bacillus subtilis Spores

Small Methods, EarlyView.
Graphene encapsulation enables liquid‐phase BSE‐SEM to visualize subsurface architecture of whole, hydrated Bacillus subtilis spores without staining. This approach is applied to visualize dormant spores and subsequent structural changes during spore germination, while imaging across a range of beam energies and Monte Carlo simulations provide a ...
Jack Bromley, Adrián Pedrazo‐Tardajos, Yongqiang Meng, Matthew C. Spink, Dogan Ozkaya, Rodney S. Ruoff, Graham Christie, Angus I. Kirkland, Judy S. Kim   +8 more
wiley   +1 more source

Synthesis of D‑FucNAc-D-ManNAcA Disaccharides Based On the Capsular Polysaccharides Staphylococcus aureus Type 5 and 8

, 2018
To gain a better understanding of the conjugation chemistry taking place at the interface of the capsular polysaccharide repeating units, described herein is the synthesis of two disaccharides.
Alexei V. Demchenko, Alexei V. Demchenko (1528714), Stephen A. Kolodziej (1600225), Stephen A. Kolodziej, Satsawat Visansirikul (1600222), Satsawat Visansirikul   +5 more
core   +1 more source

Screening of Brazilian Isolated Yeasts Reveals Multiple Potential Chassis for Industrial Biotechnology

Yeast, EarlyView.
Harnessing Brazilian microbial diversity, comprehensive phenotypic screening of 79 yeast isolates identified non‐conventional strains with superior multi‐stress tolerance and metabolic versatility compared to S. cerevisiae under industrially relevant conditions.
Giovanna R. Maklouf, Lara I. S. Sousa, Juliana Pimentel Galhardo, Cecilia Trivellin, João Pedro R. Prado, Tássia Cristina da Silva, Ana C. S. R. de Carvalho, Juliana José, Gonçalo A. G. Pereira, Marcelo F. Carazzolle, Fellipe S. B. de Mello   +10 more
wiley   +1 more source

Separation Of Isomeric Disaccharides By Traveling Wave Ion Mobility Mass Spectrometry Using Co2 As Drift Gas.

, 2015
The use of CO(2) as a massive and polarizable drift gas is shown to greatly improve peak-to-peak resolution (R(p-p) ), as compared with N(2) , for the separation of disaccharides in a Synapt G2 traveling wave ion mobility cell.
Eberlin, Marcos N, Santos, Vanessa G, Daroda, Romeu J, Fasciotti, Maíra, McCullagh, Michael, de Sá, Gilberto F, Lalli, Priscila M, Peter, Martin G, Sanvido, Gustavo B   +8 more
core   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Characterization of dermatan sulfate and chondroitin sulfate profiles during brain regeneration in Styela plicata

The FEBS Journal, EarlyView.
Adult ascidians are capable of regenerating their entire brains following injury, and glycosaminoglycans have been shown to either promote or inhibit neuritogenesis. In this study, dermatan 2,6‐disulfate (D2,6S) was identified as the predominant complex carbohydrate in the ascidian brain.
Taynan Motta Portal, Samara de Oliveira Pimentel, Bruno da Costa Rodrigues, Mauro Sérgio Gonçalves Pavão, Rodrigo Nunes da Fonseca, Cintia Monteiro de Barros   +5 more
wiley   +1 more source

α-Glucosidase inhibitory oligosaccharides derived from thinned peach fruit: preparation, identification, and effects on IR-HepG2 cells

Agricultural Products Processing and Storage
In this study, we focused on the key hypoglycemic oligosaccharide components derived from thinned peach crude polysaccharides (CPPS), elucidated their structural characteristics and hypoglycemic mechanisms, and improved the utilization of this ...
Yuze Huang, Jianfen Ye, Yingying Wei, Shu Jiang, Yi Chen, Xingfeng Shao   +5 more
doaj   +1 more source

Design and Engineering of an Artificial Bifunctional N-Deacetylase/N-Sulfotransferase for the Biosynthesis of N-Sulfated Heparosan. [PDF]

Adv Sci (Weinh)
An artificial bifunctional N‐deacetylase/N‐sulfotransferase was engineered in Escherichia coli by combining screened N‐deacetylases with an NST domain. The integrated engineering strategy improved enzyme performance. The optimized enzyme efficiently converted heparosan into N‐sulfated heparosan, addressing a key bottleneck in microbial heparin ...
Xi X, Xu R, Wang D, Yin G, Wang X, Chen H, Du G, Chen J, Kang Z.   +8 more
europepmc   +2 more sources

Common pathways and outliers in glucose catabolism across Trypanosomatidae

The FEBS Journal, EarlyView.
Trypanosomatid parasites, including Trypanosoma sp., Leishmania sp., Phytomonas sp., and Vickermania sp., share a common motif: a metabolism built around the glycosome, a unique peroxisome‐derived organelle housing the first steps of glycolysis. Yet, these organisms have evolved remarkably diverse strategies to catabolize glucose, excreting distinct ...
Fred R. Opperdoes, Mayke B. Alencar, Ariel M. Silber, Ingrid Škodová‐Sveráková, Kristína Záhonová, Vyacheslav Yurchenko   +5 more
wiley   +1 more source

Characterization of taste sensitivities to amino acids and sugars by conditioned taste aversion learning in chickens

Animal
Taste plays an essential role in regulating the feeding behaviors of animals. The present study aimed to characterize the taste sensory profiles of amino acids and sugars in chickens.
Yuta Yoshida, Shu Fujishiro, Ryota Kawai, Fuminori Kawabata   +3 more
doaj   +1 more source