Results 31 to 40 of about 118,573 (345)
Global Spine Journal, 2016 Introduction Experimental studies have demonstrated accelerated disc degeneration after various intradiscal procedures. However, there are only a few long-term follow-up studies using MRI images to confirm the progressive disc degeneration after ...
Jung-Woo Hur +3 more
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Cellular Therapy for Disc Degeneration
Spine, 2005 Review article regarding the developing field of cellular therapies for symptomatic disc degeneration.To review the rationale and discuss the results of cellular strategies that have been proposed or investigated for disc degeneration.Disc degeneration is a substantial clinical problem. Disc degeneration begins with a loss of disc cells and alterations
Anderson, D.G. +8 more
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Thickness of the ligamentum flavum of the spine and its relationship with disc degeneration
Coluna/Columna, 2014 Objective: This study investigates whether the thickening of the ligamentum flavum (LF) is correlated with disc degeneration. Methods: This retrospective study was conducted with 98 patients with chronic low back pain treated in a spinal surgery service ...
Thiago Mattar +4 more
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Degeneration of the intervertebral disc.
Arthritis research & therapy, 2003 The intervertebral disc is a cartilaginous structure that resembles articular cartilage in its biochemistry, but morphologically it is clearly different. It shows degenerative and ageing changes earlier than does any other connective tissue in the body.
Urban, J, Roberts, S
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Pathomechanism of intervertebral disc degeneration
JOR SPINE, 2020 AbstractIntervertebral disc degeneration (IDD) is the main contributor to low back pain, which is a leading cause of disability worldwide. Although substantial progress has been made in elucidating the molecular mechanisms of IDD, fundamental and long‐lasting treatments for IDD are still lacking.
Takeshi Oichi +4 more
openaire +3 more sources
Current evidence for a modulation of low back pain by human genetic variants [PDF]
, 2009 The manifestation of chronic back pain depends on structural, psychosocial, occupational and genetic influences. Heritability estimates for back pain range from 30% to 45%. Genetic influences are caused by genes affecting intervertebral disc degeneration
Aberle +200 more
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Contribution of the Endplates to Disc Degeneration [PDF]
Current Molecular Biology Reports, 2018 The endplates form the interface between the rigid vertebral bodies and compliant intervertebral discs. Proper endplate function involves a balance between conflicting biomechanical and nutritional demands. This review summarizes recent data that highlight the importance of proper endplate function and the relationships between endplate dysfunction ...
Fields, Aaron J +3 more
openaire +4 more sources
Bagcilar Medical Bulletin, 2021 Objective:To investigate the effect of current, former and passive smoking status on degeneration of lumbar intervertebral discs.Method:Three hundred and sixty patients between the ages of 20 and 70 years, who underwent lumbar spinal magnetic resonance ...
Fatma Esra Bahadır Ülger
doaj +1 more source
Roles of progenitor cells for intervertebral disc regeneration in "healer" mice [PDF]
, 2014 Student Oral Presentation Session 1INTRODUCTION: Intervertebral disc (IVD) degeneration is a major cause of back pain that can also lead to sciatica, affecting the quality of life. Current treatments are limited to salvage surgical operations. Biological
Chan, CW +4 more
core +1 more source
A population-based study of juvenile disc degeneration and its association with overweight and obesity, low back pain, and diminished functional status [PDF]
, 2011 Background: Little is known regarding juvenile disc degeneration in individuals with normal spinal alignment. Consequently, the purpose of this study was to assess the prevalence, determinants, and clinical relevance associated with juvenile disc ...
Cheung, KMC +5 more
core +1 more source