Results 11 to 20 of about 118,573 (345)
Association of abdominal obesity with lumbar disc degeneration--a magnetic resonance imaging study.
PLoS ONE, 2013 PurposeTo evaluate whether midsagittal (abdominal) obesity in magnetic resonance imaging (MRI), waist circumference (WC) and body fat percentage are associated with lumbar disc degeneration in early adulthood.MethodsWe obtained the lumbar MRI (1.5-T ...
Jani Takatalo +10 more
doaj +3 more sources
Notochord Cells in Intervertebral Disc Development and Degeneration
Journal of Developmental Biology, 2016 The intervertebral disc is a complex structure responsible for flexibility, multi-axial motion, and load transmission throughout the spine. Importantly, degeneration of the intervertebral disc is thought to be an initiating factor for back pain. Due to a
Matthew R Mccann, Cheryle A Séguin
exaly +3 more sources
Genetics of disc degeneration [PDF]
European Spine Journal, 2006 Low back pain from degenerative disc disease (DDD) is one of the most common disorders seen in general and orthopaedic practices. DDD has been attributed to the accumulation of environmental factors, primarily mechanical insults and injuries, imposed on the "normal" aging changes.
Cheung, KMC, Sham, P, Song, Y, Chan, D
openaire +3 more sources
Systemic blood plasma CCL5 and CXCL6: Potential biomarkers for human lumbar disc degeneration [PDF]
European Cells & Materials, 2016 Lumbar disc degeneration severity on magnetic resonance imaging (MRI) is associated with low back pain. Pro-inflammatory chemokines CCL5 and CXCL6 are released by induced degenerative discs, and CCL5 has been associated with discogenic back pain.
S Grad +6 more
doaj +1 more source
Paraspinal muscle degeneration and regenerative potential in a Murine model of Lumbar Disc Injury
North American Spine Society Journal, 2021 Background Context: The association between low back pain and lumbar disc degeneration is not fully characterized. One potentially overlooked factor of this process is the lumbar multifidus, which plays a role in segmental stabilization and locomotion ...
Michael R. Davies +9 more
doaj +1 more source
Biomechanics of Disc Degeneration [PDF]
Advances in Orthopedics, 2012 Disc degeneration and associated disorders are among the most debated topics in the orthopedic literature over the past few decades. These may be attributed to interrelated mechanical, biochemical, and environmental factors. The treatment options vary from conservative approaches to surgery, depending on the severity of degeneration and response to ...
V. Palepu, M. Kodigudla, V. K. Goel
openaire +3 more sources
CRISPR-Cas9-mediated loss of function of β-catenin attenuates intervertebral disc degeneration
Molecular Therapy: Nucleic Acids, 2022 Intervertebral disc degeneration is a very common medical condition causing pain and disability, and it cannot be reversed by available treatment options.
Yunshan Fan +4 more
doaj +1 more source
Journal of Translational Medicine, 2020 Background Lipid abnormality and obesity have been proposed to be associated with lumbar disc degeneration, but little is known about the effect of ‘lipid healthy but obese’ (LH-O) and ‘lipid abnormal but not obese’ (LA-NO) phenotypes on lumbar disc ...
Sheng Shi +6 more
doaj +1 more source
Frontiers in Pharmacology, 2023 Apoptosis and extracellular matrix degradation of the nucleus pulposus are the main initiators of intervertebral disc degeneration (IVDD) and can be explained by endoplasmic reticulum (ER) stress.
Yan Chen +10 more
doaj +1 more source
Lumbar intervertebral disc degeneration in collegiate rowers
Journal of Physical Fitness and Sports Medicine, 2014 The aim of this study was to clarify the prevalence and distribution of disc degeneration in collegiate rowers and investigate the relationship between disc degeneration progression and low back pain (LBP).
Chie Sekine +6 more
doaj +1 more source