Contributions of the microbiome to intestinal inflammation in a gut-on-a-chip
The intestinal microbiome affects a number of biological functions of the organism. Although the animal model is a powerful tool to study the relationship between the host and microbe, a physiologically relevant in vitro human intestinal system has still
Min Seo Jeon +9 more
doaj +1 more source
Classical Complement Pathway Inhibition in a “Human‐On‐A‐Chip” Model of Autoimmune Demyelinating Neuropathies [PDF]
Chronic autoimmune demyelinating neuropathies are a group of rare neuromuscular disorders with complex, poorly characterized etiology. Here we describe a phenotypic, human-on-a-chip (HoaC) electrical conduction model of two rare autoimmune demyelinating ...
Alonso‐Alonso, Miguel +21 more
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A Comprehensive Review of Organ-on-a-Chip Technology and Its Applications
Organ-on-a-chip (OOC) is an emerging technology that simulates an artificial organ within a microfluidic cell culture chip. Current cell biology research focuses on in vitro cell cultures due to various limitations of in vivo testing.
Negar Farhang Doost +1 more
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Intestine‐on‐a‐chip for intestinal disease study and pharmacological research
Intestinal diseases seriously affect the quality of life. The assays for intestinal disease study based on two‐dimensional in vitro cell culture and animal models fail to model human physiology and pathophysiology accurately. As a bridge between in vitro
Dongxue Zhang, Liang Qiao
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Self-assembled cellulose nanofiber-carbon nanotube nanocomposite films with anisotropic conductivity [PDF]
In this study, a nanocellulose-based material showing anisotopic conductivity is introduced. The material has up to 1000 times higher conductivity along the dry-line boundary direction than along the radial direction.
Björkqvist, Tomas +9 more
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Precision oncology using ex vivo technology: a step towards individualised cancer care? [PDF]
Despite advances in cancer genomics and the increased use of genomic medicine, metastatic cancer is still mostly an incurable and fatal disease. With diminishing returns from traditional drug discovery strategies, and high clinical failure rates, more ...
Allen, R. +11 more
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Microfluidic preparation of optical sensors for biomedical applications
Optical biosensors are platforms that translate biological information into detectable optical signals, and have extensive applications in various fields due to their characteristics of high sensitivity, high specificity, dynamic sensing, etc.
Qiao Wang +5 more
doaj +1 more source
Numerical modeling of the fiber deposition flow in extrusion-based 3D bioprinting [PDF]
Extrusion bioprinting involves the deposition of bioinks in a layer-wise fashion to build 3D structures that mimic natural living systems\u27 behavior in tissue engineering. Hydrogels are the most common bioinks, in which their viscosity properties are
Talluri, Dhanvanth Jaya
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Multi-Omics for the Understanding of Brain Diseases [PDF]
Omics technologies such as proteomics, genomics, and metabolomics are widely applied for the identification and characterization of new molecular signatures. However, molecular profiling that makes it possible to understand neurodegenerative diseases has
core +1 more source
Micro/nanofluidic and lab-on-a-chip devices for biomedical applications [PDF]
Micro/Nanofluidic and lab-on-a-chip devices have been increasingly used in biomedical research [1]. Because of their adaptability, feasibility, and cost-efficiency, these devices can revolutionize the future of preclinical technologies.
Carvalho, Violeta +2 more
core +1 more source

