Results 31 to 40 of about 193,025 (292)
Organoids/organs-on-a-chip: new frontiers of intestinal pathophysiological models.
Lab on a Chip, 2023 Organoids/organs-on-a-chip open up new frontiers for basic and clinical research of intestinal diseases. Species-specific differences hinder research on animal models, while organoids are emerging as powerful tools due to self-organization from stem ...
Lei Wu +5 more
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Frontiers in Molecular Neuroscience, 2023 The blood-brain barrier (BBB) is a highly selective barrier that ensures a homeostatic environment for the central nervous system (CNS). BBB dysfunction, inflammation, and immune cell infiltration are hallmarks of many CNS disorders, including multiple ...
A. L. Nair +7 more
semanticscholar +1 more source
Organ-on-a-chip: a more promising in vitro model [PDF]
Jichu yixue yu linchuangTraditional in vitro models have inevitable limitations and there are significant differences in assessing drug efficacy and side effects as compared to human trials.
YANG Zhenli, XIA Yujia, LIU Yuqin
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Microdevice Platform for In Vitro Nervous System and Its Disease Model
Bioengineering, 2017 The development of precise microdevices can be applied to the reconstruction of in vitro human microenvironmental systems with biomimetic physiological conditions that have highly tunable spatial and temporal features.
Jin-Ha Choi +2 more
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JCI Insight, 2023 Necrotizing enterocolitis (NEC) is a deadly gastrointestinal disease of premature infants that is associated with an exaggerated inflammatory response, dysbiosis of the gut microbiome, decreased epithelial cell proliferation, and gut barrier disruption ...
Wyatt E. Lanik +17 more
semanticscholar +1 more source
Lab-on-a-Chip for Cardiovascular Physiology and Pathology
Micromachines, 2020 Lab-on-a-chip technologies have allowed researchers to acquire a flexible, yet relatively inexpensive testbed to study one of the leading causes of death worldwide, cardiovascular disease.
Sean Beverung +2 more
doaj +1 more source
Contributions of the microbiome to intestinal inflammation in a gut-on-a-chip
Nano Convergence, 2022 The intestinal microbiome affects a number of biological functions of the organism. Although the animal model is a powerful tool to study the relationship between the host and microbe, a physiologically relevant in vitro human intestinal system has still
Min Seo Jeon +9 more
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Using Biosensors to Study Organoids, Spheroids and Organs-on-a-Chip: A Mechanobiology Perspective
Biosensors, 2023 The increasing popularity of 3D cell culture models is being driven by the demand for more in vivo-like conditions with which to study the biochemistry and biomechanics of numerous biological processes in health and disease.
M. S. Yousafzai, John A. Hammer
semanticscholar +1 more source
Frontiers in microfluidics, a teaching resource review [PDF]
, 2019 This is a literature teaching resource review for biologically inspired microfluidics courses or exploring the diverse applications of microfluidics. The structure is around key papers and model organisms.
Merrin, Jack
core +2 more sources
Nature Biomedical Engineering, 2022 Rapid, accurate and frequent detection of the RNA of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) and of serological host antibodies to the virus would facilitate the determination of the immune status of individuals who have Coronavirus ...
Devora Najjar +15 more
semanticscholar +1 more source