Results 41 to 50 of about 192,797 (169)
Pancreatic islet organoids-on-a-chip: how far have we gone?
Journal of Nanobiotechnology, 2022 Diabetes mellitus (DM) is a disease caused by dysfunction or disruption of pancreatic islets. The advent and development of microfluidic organoids-on-a-chip platforms have facilitated reproduce of complex and dynamic environment for tissue or organ ...
Jiaxiang Yin +5 more
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Pyk2 overexpression in postsynaptic neurons blocks amyloid β1-42-induced synaptotoxicity in microfluidic co-cultures [PDF]
, 2020 Recent meta-analyses of genome-wide association studies identified a number of genetic risk factors of Alzheimer’s disease; however, little is known about the mechanisms by which they contribute to the pathological process. As synapse loss is observed at
Amouyel, Philippe +14 more
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A novel vascularized urethra-on-a-chip model
Scientific ReportsThe male urethra transports urine and semen. Any disease of the male urethra, hindering normal voiding or ejaculation, has a major impact on quality of life. Urethral stricture disease is common and molecular research into urethral strictures is hampered
Aina Casademont-Roca +5 more
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Neuromuscular disease modeling on a chip
Disease Models & Mechanisms, 2020 Organs-on-chips are broadly defined as microfabricated surfaces or devices designed to engineer cells into microscale tissues with native-like features and then extract physiologically relevant readouts at scale.
Jeffrey W. Santoso, Megan L. McCain
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Survey on prediction, classification and tracking of neurodegenerative diseases [PDF]
Neurodegenerative diseases (NDD) such as Alzheimer's, Parkinson's, and Huntington's disease are complex conditions that progressively impair neurological function.
Dhavalgi, Veena, Ranganatha, H R
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3D organotypic cell structures for drug development and Microorganism-Host interaction research [PDF]
, 2021 The article describes a new method of tissue engineering, which is based on the use of three-dimensional multicellular constructs consisting of stem cells that mimic the native tissue in vivo ...
Avtina, T. V. +5 more
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Bioprinting of three-dimensional culture models and organ-on-a-chip systems [PDF]
, 2017 Multimaterial bioprinting technologies offer promising avenues to create mini-organ models with enhanced tissue heterogeneity and complexity. This article focuses on the application of three-dimensional bioprinting to fabricate organ-on-a-chip systems ...
Huang, YYS, Liu, Y, Zhang, D
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IMMUNITY-ON-A-CHIP Microfluidic Devices for Immunoengineering [PDF]
, 2017 Immunitet-på-mikrobrikke Mikrofluidiske innretninger for immunologisk forskning og utvikling Sammendrag: Det siste tiåret har mikrofluidteknologi, dvs væskestrømmer i mikroskala basert på prosesser fra halvlederindustrien, gitt et betydelig løfte om ...
Moura Rosa, Patrícia
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BiomimeticsThe liver is a vital organ responsible for a broad range of metabolic functions, including glucose and lipid metabolism, detoxification, and protein synthesis.
Jingyeong Yun +2 more
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Vasculature-On-A-Chip for In Vitro Disease Models
Bioengineering, 2017 Vascularization, the formation of new blood vessels, is an essential biological process. As the vasculature is involved in various fundamental physiological phenomena and closely related to several human diseases, it is imperative that substantial ...
Seunggyu Kim +3 more
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