Results 181 to 190 of about 65,779 (239)

Murine ADAM15 Deficiency Is Associated With Atrial Remodelling and Atrial Arrhythmia Susceptibility. [PDF]

open access: yesEur J Clin Invest
Bapat A   +6 more
europepmc   +1 more source

Molecular Cloning of Disintegrin-like Transcript BA-5A from a Bitis arietans Venom Gland cDNA Library: A Putative Intermediate in the Evolution of the Long-Chain Disintegrin Bitistatin

open access: yesJournal of Molecular Evolution, 2006
We report the cloning and sequence analysis of BA-5A from a venom gland cDNA library of the puff adder, Bitis arietans, that encodes a novel ECD-disintegrin-like domain. BA-5A is a unique PII disintegrin.
Juan J. Calvete   +2 more
exaly   +2 more sources

Disintegrins

Current Drug Target -Cardiovascular & Hematological Disorders, 2004
The existence of disintegrins, non-enzymatic, small molecular weight proteins from viper venom, has been known for 2 decades, and their impact on cellular research has been substantial and far-reaching. Disintegrins have been the molecular scaffold used in the design of therapeutics for the prevention of thrombosis and cancer.
Mary Ann, McLane   +4 more
openaire   +2 more sources

Disintegrins in health and disease

Frontiers in Bioscience, 2008
Few of the proteins isolated and characterized from snake venom have proven to be more chemically diverse, exquisitely specific or promiscuously active than the family known as disintegrins. These small proteins have shown structural homology with hundreds of cell surface molecules from plants and animals other than snakes, and their precise mimicry of
Mary Ann, McLane   +2 more
openaire   +2 more sources

Disintegrin and Metalloproteinases (ADAMs [A Disintegrin and Metalloproteinase] and ADAMTSs [ADAMs With a Thrombospondin Motif]) in Aortic Aneurysm

Hypertension, 2022
Aortic aneurysm is a complex pathology that can be lethal if not detected in time. Although several molecular mechanisms and pathways have been identified to be involved in aortic aneurysm development and growth, the current lack of an effective pharmacological treatment highlights the need for a more thorough understanding of the factors that regulate
Tolga Kilic   +3 more
openaire   +2 more sources

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