Results 31 to 40 of about 523,220 (184)

Amphiphilic blockers punch through a mutant CLC-0 pore. [PDF]

open access: yes, 2009
Intracellularly applied amphiphilic molecules, such as p-chlorophenoxy acetate (CPA) and octanoate, block various pore-open mutants of CLC-0. The voltage-dependent block of a particular pore-open mutant, E166G, was found to be multiphasic. In symmetrical
Chen, Tsung-Yu, Zhang, Xiao-Dong
core   +2 more sources

Direct Potentiometric Determination of Fluoride Species by Using Ion-Selective Fluoride Electrode

open access: yesInternational Journal of Electrochemical Science, 2012
A novel approach and method for potentiometric determination of acid dissociation constant (Ka) of hydrofluoric acid are described. Proposed method is based on using commercial fluoride ISE (FISE) as very inexpensive, simple and reasonably fast method ...
Ante Prkić   +3 more
doaj   +1 more source

Charge regulation: a generalized boundary condition?

open access: yes, 2016
The three most commonly-used boundary conditions for charged colloidal systems are constant charge (insulator), constant potential (conducting electrode) and charge regulation (ionizable groups at the surface).
Andelman, David   +2 more
core   +1 more source

Systems analysis shows that thermodynamic physiological and pharmacological fundamentals drive COVID‐19 and response to treatment

open access: yesPharmacology Research & Perspectives, 2022
Why a systems analysis view of this pandemic? The current pandemic has inflicted almost unimaginable grief, sorrow, loss, and terror at a global scale. One of the great ironies with the COVID‐19 pandemic, particularly early on, is counter intuitive.
Richard J. Head   +7 more
doaj   +1 more source

Force Modulating Dynamic Disorder: Physical Theory of Catch-slip bond Transitions in Receptor-Ligand Forced Dissociation Experiments

open access: yes, 2006
Recently experiments showed that some adhesive receptor-ligand complexes increase their lifetimes when they are stretched by mechanical force, while the force increase beyond some thresholds their lifetimes decrease.
A. Messiah   +6 more
core   +1 more source

Sonochemical Degradation of Perfluorooctane Sulfonate (PFOS) and Perfluorooctanoate (PFOA) in Landfill Groundwater: Environmental Matrix Effects [PDF]

open access: yes, 2008
Perfluorinated chemicals such as perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) are environmentally persistent and recalcitrant to most conventional chemical and microbial treatment technologies.
Cheng, Jie   +4 more
core   +3 more sources

Consideration of the contribution of chemical (non-enzymatic) conversion of substrate in the general mechanism of enzyme reaction [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2019
When enzyme-catalyzed reactions are studied, it is necessary to take into account the contribution of the chemical (non-enzymatic) conversion of the substrate to the product, which is carried out together with the enzyme-catalyzed conversion of the ...
S. O. Kosterin   +2 more
doaj   +1 more source

Electron Transfer Precedes ATP Hydrolysis during Nitrogenase Catalysis [PDF]

open access: yes, 2013
The biological reduction of N2 to NH3 catalyzed by Mo-dependent nitrogenase requires at least eight rounds of a complex cycle of events associated with ATP-driven electron transfer (ET) from the Fe protein to the catalytic MoFe protein, with each ET ...
Antony, Edwin   +7 more
core   +2 more sources

Interactions of amino terminal domains of Shaker K channels with a pore blocking site studied with synthetic peptides [PDF]

open access: yes, 1993
Synthetic peptides of the five alternative NH2-terminal sequences of Shaker when applied to the cytoplasmic side of ShB channels that have an NH2-terminal deletion (ShB delta 6-46) block the channel with potencies correlated with the rate of inactivation
Aldrich, Richard W   +1 more
core   +3 more sources

Generation of Red-Shifted Cameleons for Imaging Ca2+ Dynamics of the Endoplasmic Reticulum

open access: yesSensors, 2015
Cameleons are sophisticated genetically encoded fluorescent probes that allow quantifying cellular Ca2+ signals. The probes are based on Förster resonance energy transfer (FRET) between terminally located fluorescent proteins (FPs), which move together ...
Markus Waldeck-Weiermair   +12 more
doaj   +1 more source

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