Results 11 to 20 of about 41,703 (248)
Dissolution enhancement of albendazole through nanocrystal formulation
Albendazole, a BCS class II drug, has poor dissolution characteristic. In order to enhance dissolution nanocrystals were prepared by antisolvent precipitation process using PVP K-30(0.05%,0.1%,0.2%,0.4%) as stabilizer.
D Krishna Koradia, H Rajesh Parikh
doaj +3 more sources
Insights into the Mechanism of Enhanced Dissolution in Solid Crystalline Formulations
Solid dispersions are a promising approach to enhance the dissolution of poorly water-soluble drugs. Solid crystalline formulations show a fast drug dissolution and a high thermodynamic stability.
Anna Justen +2 more
doaj +3 more sources
Dissolution enhancement of Tibolone by micronization technique
Objectives: Tibolone is an estrogen-like compound used for the treatment of the symptoms associated with the menopausal transition and also for the treatment of osteoporosis.
Kailash Bansal +3 more
doaj +2 more sources
Dissolution Enhancement of Lycopene Compacts by Liquisolid Technique. [PDF]
Bortezomib (BTZ) functions as an androgen receptor signalling inhibitor, is used for the treatment of prostate cancer, and has been sanctioned by the United States Food and Drug Administration. The medicinal applications of BTZ are impeded by low solubility, first-pass metabolism, and restricted bioavailability.
Sharma S, Singh J, Singh S.
europepmc +6 more sources
Comments on "Dissolution Enhancement of Atorvastatin Calcium by Cocrystallization". [PDF]
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Emami S, Shayanfar A.
europepmc +5 more sources
Enhancing Lignin Dissolution and Extraction: The Effect of Surfactants [PDF]
The dissolution and extraction of lignin from biomass represents a great challenge due to the complex structure of this natural phenolic biopolymer. In this work, several surfactants (i.e., non-ionic, anionic, and cationic) were used as additives to enhance the dissolution efficiency of model lignin (kraft) and to boost lignin extraction from pine ...
Elodie Melro +4 more
openaire +6 more sources
Liquisolid Tablets for Dissolution Enhancement of a Hypolipidemic Drug. [PDF]
This investigation was aimed to improve the dissolution rate of the poorly soluble drug lovastatin, by formulating it as a liquisolid compact. Different liquisolid compacts were prepared using mathematical formulae to calculate the required quantities of powder and liquid ingredients to produce acceptably flowable and compressible admixture.
Patel DS, Pipaliya RM, Surti N.
europepmc +4 more sources
Enhanced carbonate dissolution: [PDF]
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Rau, Greg H., Caldeira, Ken
openaire +2 more sources
Enhanced steady-state dissolution flux in reactive convective dissolution [PDF]
Chemical reactions can enhance the dissolution flux during the convective dissolution of one phase into a fluid host phase.
V. Loodts +3 more
openaire +4 more sources
Critical Excipient Properties for the Dissolution Enhancement of Phenytoin. [PDF]
Solubility-enhancing amorphous solid dispersions can aid in the oral delivery of hydrophobic, poorly soluble drugs. Effective solid dispersion excipients enable high supersaturation drug concentrations over biologically relevant time scales. The critical characteristics of an excipient that allow it to work well in a solid dispersion system are not ...
Johnson LM, Hillmyer MA.
europepmc +5 more sources

