Results 11 to 20 of about 5,089,703 (351)
Road and bridge construction across gypsum karst in England [PDF]
, 2002 Gypsum karst problems in the Permian and Triassic sequences of England have caused difficult conditions for bridge and road construction. In Northern England, the Ripon Bypass crosses Permian strata affected by active gypsum karst and severe subsidence ...
Anthony H Cooper +20 more
core +3 more sources
Pharmaceutical co-crystals of posaconazole for improvement of physicochemical properties [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2022 Posaconazole exerts an extended spectrum of antifungal activity against various strains of clinically relevant moulds and yeasts. In recent years, antifungal triazole posaconazole has become increasingly important for the prophylaxis and treatment of ...
Monika Nijhawan +4 more
doaj +1 more source
Improving Dissolution and Cytotoxicity by Forming Multidrug Crystals [PDF]
Molecules, 2020 Both rosiglitazone and metformin have effects on blood glucose regulation and the proliferation of liver cancer cells. Combination therapy with these two drugs is common and effective for the treatment of diabetes in the clinic, however, the application of these two drugs is influenced by the poor dissolution of rosiglitazone and the gastrointestinal ...
Bian, Xufei +7 more
openaire +3 more sources
Dissolution control and stability improvement of silica nanoparticles in aqueous media
Journal of nanoparticle research, 2023 Silica nanoparticles have become an important tool in material sciences, nanomedicine, biotechnology, and pharmaceutics, with recent suggested applications also in environmental sciences.
L. Spitzmüller +5 more
semanticscholar +1 more source
Pharmaceutics, 2020 The aim of this work was to evaluate the effectiveness of mesoporous clays or silicas to develop fast-dissolving glyburide tablets based on a liquisolid approach.
Marzia Cirri +3 more
doaj +1 more source
Solubility improvement of progesterone from solid dispersions prepared by solvent evaporation and co-milling [PDF]
, 2020 The aim of this contribution was to evaluate the impact of processing methods and polymeric carriers on the physicochemical properties of solid dispersions of the poorly soluble drug progesterone (PG). Five polymers: hydroxypropyl methylcellulose (HPMC),
Al-Obaidi, Hisham +3 more
core +1 more source
Nanotechnology Versus other Techniques in Improving Drug Dissolution [PDF]
Current Pharmaceutical Design, 2014 Many newly discovered drug molecules have low aqueous solubility, which results in low bioavailability. One way to improve their dissolution is to formulate them as nanoparticles, which have high specific surface areas, consequently increasing the dissolution rate and solubility. Nanoparticles can be produced via top-down or bottom-up methods. Top-down
Kwok, PCL, Chan, HK
openaire +4 more sources
Cellulose Dissolution in Ionic Liquid under Mild Conditions: Effect of Hydrolysis and Temperature
Fibers, 2021 This study investigated the effect of acid hydrolysis of cellulose on its dissolution under mild conditions in ionic liquid, 1-butyl-3-methylimidazolium acetate/N,N-dimethylacetamide (BMIMAc/DMAc).
Sanjit Acharya +2 more
doaj +1 more source
Polytechnic Journal, 2021 Drugs which fall into Class II of Biopharmaceutical Classification System suffer from poor aqueous solubility that limits the dissolution and oral bioavailability.
Hemn L. Qader +2 more
doaj +1 more source
Improved Formazan Dissolution for Bacterial MTT Assay
Microbiology Spectrum, 2021 Reduction of the water-soluble tetrazolium salt 3-(4,5-dimethylthiazol)-2,5 diphenyl-tetrazolium bromide (MTT) to purple, water-insoluble formazan is commonly used for assessment of cell viability and proliferation. Spectrophotometric detection of formazan requires its solubilization.
openaire +4 more sources