Results 21 to 30 of about 5,089,703 (351)
Background: Bioactive oils of natural origin have gained huge interests from health care professionals and patients. Objective: To design a bioactive self-nanoemulsifying drug delivery system (Bio-SNEDDS) comprising curcumin (CUR) and piperine (PP) by ...
Mohsin Kazi +5 more
doaj +1 more source
Flufenamic acid (FFA) is a non-steroidal anti-inflammatory drug characterised by a low solubility and problems of variable dissolution rate and bio-inequivalence.
Francesca Maestrelli +4 more
doaj +1 more source
Isostructural cocrystals of metaxalone with improved dissolution characteristics
Metaxalone forms isostructural cocrystals with nicotinamide and salicylamide that offer a solubility advantage compared to the native drug. A drug–drug homosynthon is retained in all the cocrystal structures.
Sunil Kumar Gohel +5 more
openaire +3 more sources
Liquisolid Systems to Improve the Dissolution of Furosemide [PDF]
A liquisolid system has the ability to improve the dissolution properties of poorly water soluble drugs. Liquisolid compacts are flowing and compactable powdered forms of liquid medications. The aim of this study was to enhance the in vitro dissolution properties of the practically water insoluble loop diuretic furosemide, by utilising liquisolid ...
Akinlade, Babatunde +3 more
openaire +3 more sources
Dissolution improvement of high drug-loaded solid dispersion [PDF]
This study focused on an investigation of a high drug-loaded solid dispersion system consisting of drug, carrier, and surfactant. Solid dispersions of a water-insoluble ofloxacin (OFX) with polyethylene glycol (PEG) of different molecular weights, namely binary solid dispersion systems, were prepared at drug to carrier not less than 5:5. Polysorbate 80,
Siriporn, Okonogi +1 more
openaire +2 more sources
Chemo-mechanical modeling of artificially and naturally bonded soils [PDF]
Chemo-mechanical effects are known to be significant in a number of applications in modern geomechanics, ranging from slope stability assessment to soil improvement and CO2 sequestration.
Cecinato, Francesco +2 more
core +2 more sources
In this present research, an attempt has been made to address the influence of drug-coformer stoichiometric ratio on cocrystal design and its impact on improvement of solubility and dissolution, as well as bioavailability of poorly soluble telmisartan ...
Manami Dhibar +7 more
doaj +1 more source
Albendazole Solid Dispersions: Influence of Dissolution Medium Composition on In Vitro Drug Release [PDF]
The rate-limiting step to drug absorption is often dissolution from the dosage form, especially for poorly soluble com-pounds. Two possibilities for improving the dissolution of these drugs are to increase the available surface area and to im-prove their
Allemandi, Daniel Alberto +4 more
core +1 more source
A Systems Thinking Approach to Redesigning the Patient Experience to Reduce 30 Day Hospital Readmission [PDF]
INTRODUCTION The cost of medical care is spiraling out of control, and one of the many reasons is lack of preventative care, poor communication to the patient and primary caregiver(s) both in an inpatient and outpatient setting.
DePrince, RN, BA, CCRN, SCRN, Maureen +6 more
core +2 more sources
The dissolution rate of anhydrous acyclovir was improved by the preparation of physical mixtures and solid dispersions with the non-ionic polymer Pluronic F127 using the kneading method at different drug-to-polymer ratios.
Karolewicz Bożena +3 more
doaj +1 more source

