Results 21 to 30 of about 5,089,703 (351)

Bioactive Self-Nanoemulsifying Drug Delivery Systems (Bio-SNEDDS) for Combined Oral Delivery of Curcumin and Piperine

open access: yesMolecules, 2020
Background: Bioactive oils of natural origin have gained huge interests from health care professionals and patients. Objective: To design a bioactive self-nanoemulsifying drug delivery system (Bio-SNEDDS) comprising curcumin (CUR) and piperine (PP) by ...
Mohsin Kazi   +5 more
doaj   +1 more source

Role of Cyclodextrins and Drug Solid State Properties on Flufenamic Acid Dissolution Performance from Tablets

open access: yesPharmaceutics, 2022
Flufenamic acid (FFA) is a non-steroidal anti-inflammatory drug characterised by a low solubility and problems of variable dissolution rate and bio-inequivalence.
Francesca Maestrelli   +4 more
doaj   +1 more source

Isostructural cocrystals of metaxalone with improved dissolution characteristics

open access: yesRSC Advances, 2021
Metaxalone forms isostructural cocrystals with nicotinamide and salicylamide that offer a solubility advantage compared to the native drug. A drug–drug homosynthon is retained in all the cocrystal structures.
Sunil Kumar Gohel   +5 more
openaire   +3 more sources

Liquisolid Systems to Improve the Dissolution of Furosemide [PDF]

open access: yesScientia Pharmaceutica, 2010
A liquisolid system has the ability to improve the dissolution properties of poorly water soluble drugs. Liquisolid compacts are flowing and compactable powdered forms of liquid medications. The aim of this study was to enhance the in vitro dissolution properties of the practically water insoluble loop diuretic furosemide, by utilising liquisolid ...
Akinlade, Babatunde   +3 more
openaire   +3 more sources

Dissolution improvement of high drug-loaded solid dispersion [PDF]

open access: yesAAPS PharmSciTech, 2006
This study focused on an investigation of a high drug-loaded solid dispersion system consisting of drug, carrier, and surfactant. Solid dispersions of a water-insoluble ofloxacin (OFX) with polyethylene glycol (PEG) of different molecular weights, namely binary solid dispersion systems, were prepared at drug to carrier not less than 5:5. Polysorbate 80,
Siriporn, Okonogi   +1 more
openaire   +2 more sources

Chemo-mechanical modeling of artificially and naturally bonded soils [PDF]

open access: yes, 2019
Chemo-mechanical effects are known to be significant in a number of applications in modern geomechanics, ranging from slope stability assessment to soil improvement and CO2 sequestration.
Cecinato, Francesco   +2 more
core   +2 more sources

Critical Analysis and Optimization of Stoichiometric Ratio of Drug-Coformer on Cocrystal Design: Molecular Docking, In Vitro and In Vivo Assessment

open access: yesPharmaceuticals, 2023
In this present research, an attempt has been made to address the influence of drug-coformer stoichiometric ratio on cocrystal design and its impact on improvement of solubility and dissolution, as well as bioavailability of poorly soluble telmisartan ...
Manami Dhibar   +7 more
doaj   +1 more source

Albendazole Solid Dispersions: Influence of Dissolution Medium Composition on In Vitro Drug Release [PDF]

open access: yes, 2014
The rate-limiting step to drug absorption is often dissolution from the dosage form, especially for poorly soluble com-pounds. Two possibilities for improving the dissolution of these drugs are to increase the available surface area and to im-prove their
Allemandi, Daniel Alberto   +4 more
core   +1 more source

A Systems Thinking Approach to Redesigning the Patient Experience to Reduce 30 Day Hospital Readmission [PDF]

open access: yes, 2018
INTRODUCTION The cost of medical care is spiraling out of control, and one of the many reasons is lack of preventative care, poor communication to the patient and primary caregiver(s) both in an inpatient and outpatient setting.
DePrince, RN, BA, CCRN, SCRN, Maureen   +6 more
core   +2 more sources

Physicochemical characterization and dissolution studies of acyclovir solid dispersions with Pluronic F127 prepared by the kneading method

open access: yesActa Pharmaceutica, 2016
The dissolution rate of anhydrous acyclovir was improved by the preparation of physical mixtures and solid dispersions with the non-ionic polymer Pluronic F127 using the kneading method at different drug-to-polymer ratios.
Karolewicz Bożena   +3 more
doaj   +1 more source

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